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Benign Prostate Hyperplasia and Prostatic Tumor

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Geriatric Imaging

Abstract

Rising life expectancy has swollen the ranks of men of middle age and beyond. These individuals have a 43 % risk of symptoms of benign prostatic hyperplasia (BPH) and a 9 % chance of being diagnosed with prostate cancer. Although not always life-threatening, prostate diseases are often associated with a significant reduction in quality of life not only for the sufferer but also for his partner. Men beyond middle age are increasingly reluctant to accept restrictions on their day-to-day activities as they grow older. As a consequence, prostate diseases are now acknowledged as an important determinant of men’s health and therefore worthy of proper scrutiny, treatment, and enhanced research.

In this chapter, the role of imaging modalities in evaluation of prostate disorders in elderly is illustrated, with emphasis both on current clinical practice and on the evolving imaging modalities that will affect treatment in the future.

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Abbreviations

BPH:

Benign prostatic hyperplasia

CT:

Computed tomography

FCH:

[18F]fluorocholine

FDG:

[18F]fluorodeoxyglucose

LUTS:

Lower urinary tract symptoms

MR:

Magnetic resonance

MRI:

Magnetic resonance imaging

PET:

Positron emission tomography

PSA:

Prostate-specific antigen

TRUS:

Transrectal ultrasound

References

  • Aarnink RG, De La Rosette JJ et al (1996) Reproducibility of prostate volume measurements from transrectal ultrasonography by an automated and a manual technique. Br J Urol 78(2):219–223

    Article  PubMed  CAS  Google Scholar 

  • Aarnink RG, Beerlage HP et al (1998) Transrectal ultrasound of the prostate: innovations and future applications. J Urol 159(5):1568–1579

    Article  PubMed  CAS  Google Scholar 

  • Alonzi R, Padhani AR et al (2007) Dynamic contrast enhanced MRI in prostate cancer. Eur J Radiol 63(3):335–350

    Article  PubMed  Google Scholar 

  • American Urological Association (AUA) (2000) Prostate-specific antigen (PSA) best practice policy. Oncology 14(2):267–272, 277–268

    Google Scholar 

  • Arredondo SA, Downs TM et al (2004) Watchful waiting and health related quality of life for patients with localized prostate cancer: data from CaPSURE. J Urol 172(5 Pt 1):1830–1834

    Article  PubMed  Google Scholar 

  • Atri M, Gertner MR et al (2009) Contrast-enhanced ultrasonography for real-time monitoring of interstitial laser thermal therapy in the focal treatment of prostate cancer. Can Urol Assoc J 3(2):125–130

    PubMed  Google Scholar 

  • Barentsz JO, Engelbrecht M et al (1999) Fast dynamic gadolinium-enhanced MR imaging of urinary bladder and prostate cancer. J Magn Reson Imaging 10(3):295–304

    Article  PubMed  CAS  Google Scholar 

  • Beauregard JM, Williams SG et al (2010) Pilot comparison of F-fluorocholine and F-fluorodeoxyglucose PET/CT with conventional imaging in prostate cancer. J Med Imaging Radiat Oncol 54(4):325–332

    Article  PubMed  Google Scholar 

  • Beheshti M, Vali R et al (2009) The use of F-18 choline PET in the assessment of bone metastases in prostate cancer: correlation with morphological changes on CT. Mol Imaging Biol 11(6):446–454

    Article  PubMed  Google Scholar 

  • Berardinelli F, Hinh P et al (2009) Minimally invasive surgery in the management of benign prostatic hyperplasia. Minerva Urol Nefrol 61(3):269–289

    PubMed  CAS  Google Scholar 

  • Berger AP, Deibl M et al (2005) Vascular damage as a risk factor for benign prostatic hyperplasia and erectile dysfunction. BJU Int 96(7):1073–1078

    Article  PubMed  Google Scholar 

  • Bertolotto M, Trincia E et al (2009) Effect of Tadalafil on prostate haemodynamics: preliminary evaluation with contrast-enhanced US. La Radiol med 114(7):1106–1114

    Article  CAS  Google Scholar 

  • Beyersdorff D, Taupitz M et al (2002) Patients with a history of elevated prostate-specific antigen levels and negative transrectal US-guided quadrant or sextant biopsy results: value of MR imaging. Radiology 224(3):701–706

    Article  PubMed  Google Scholar 

  • Bilhim T, Pisco JM et al (2011) Prostatic arterial supply: demonstration by multirow detector angio CT and catheter angiography. Eur Radiol 21(5):1119–1126

    Article  PubMed  Google Scholar 

  • Blatt AH, Titus J et al (2008) Ultrasound measurement of bladder wall thickness in the assessment of voiding dysfunction. J Urol 179(6):2275–2279

    Article  PubMed  Google Scholar 

  • Borek D, Butcher D et al (1990) Relationship of age to histologic grade in prostate cancer. Prostate 16(4):305–311

    Article  PubMed  CAS  Google Scholar 

  • Brett AS, Ablin RJ (2011) Prostate-cancer screening – what the U.S. Preventive Services Task Force left out. N Engl J Med 365(21):1949–1951

    Article  PubMed  CAS  Google Scholar 

  • Carroll PR, Coakley FV et al (2006) Magnetic resonance imaging and spectroscopy of prostate cancer. Rev Urol 8(Suppl 1):S4–S10

    PubMed  Google Scholar 

  • Chapple CR, Roehrborn CG (2006) A shifted paradigm for the further understanding, evaluation, and treatment of lower urinary tract symptoms in men: focus on the bladder. Eur Urol 49(4):651–658

    Article  PubMed  Google Scholar 

  • Cheng HL, Haider MA et al (2008) MRI and contrast-­enhanced ultrasound monitoring of prostate microwave focal thermal therapy: an in vivo canine study. J Magn Reson Imaging 28(1):136–143

    Article  PubMed  Google Scholar 

  • Chia SJ, Heng CT et al (2003) Correlation of intravesical prostatic protrusion with bladder outlet obstruction. BJU Int 91(4):371–374

    Article  PubMed  CAS  Google Scholar 

  • Cimitan M, Bortolus R et al (2006) [18F]fluorocholine PET/CT imaging for the detection of recurrent prostate cancer at PSA relapse: experience in 100 consecutive patients. Eur J Nucl Med Mol Imaging 33(12):1387–1398

    Article  PubMed  Google Scholar 

  • Collins DJ, Padhani AR (2004) Dynamic magnetic resonance imaging of tumor perfusion. Approaches and biomedical challenges. IEEE Eng Med Biol Mag 23(5):65–83

    Article  PubMed  Google Scholar 

  • Concato J, Wells CK et al (2006) The effectiveness of screening for prostate cancer: a nested case–control study. Arch Intern Med 166(1):38–43

    Article  PubMed  Google Scholar 

  • Cornud F, Flam T et al (2002) Extraprostatic spread of clinically localized prostate cancer: factors predictive of pT3 tumor and of positive endorectal MR imaging examination results. Radiology 224(1):203–210

    Article  PubMed  Google Scholar 

  • de Jong IJ, Pruim J et al (2003) Preoperative staging of pelvic lymph nodes in prostate cancer by 11C-choline PET. J Nucl Med 44(3):331–335

    PubMed  Google Scholar 

  • DeGrado TR, Coleman RE et al (2001) Synthesis and evaluation of 18F-labeled choline as an oncologic tracer for positron emission tomography: initial findings in prostate cancer. Cancer Res 61(1):110–117

    PubMed  CAS  Google Scholar 

  • DeGrado TR, Kwee SA et al (2007) The impact of urinary excretion of (18)F-labeled choline analogs. J Nucl Med 48(7):1225

    Article  PubMed  Google Scholar 

  • Djavan B, Ravery V et al (2001) Prospective evaluation of prostate cancer detected on biopsies 1, 2, 3 and 4: when should we stop? J Urol 166(5):1679–1683

    Article  PubMed  CAS  Google Scholar 

  • Donatucci CF, Brock GB et al (2011) Tadalafil administered once daily for lower urinary tract symptoms secondary to benign prostatic hyperplasia: a 1-year, open-label extension study. BJU Int 107(7):1110–1116

    Article  PubMed  Google Scholar 

  • Doo CK, Uh HS (2009) Anatomic configuration of prostate obtained by noninvasive ultrasonography can predict clinical voiding parameters for determining BOO in men with LUTS. Urology 73(2):232–236

    Article  PubMed  Google Scholar 

  • Emonds KM, Swinnen JV et al (2009) Molecular imaging of prostate cancer. Methods 48(2):193–199

    Article  PubMed  CAS  Google Scholar 

  • Engelbrecht MR, Huisman HJ et al (2003) Discrimination of prostate cancer from normal peripheral zone and central gland tissue by using dynamic contrast-enhanced MR imaging. Radiology 229(1):248–254

    Article  PubMed  Google Scholar 

  • Farsad M, Schiavina R et al (2005) Detection and localization of prostate cancer: correlation of (11)C-choline PET/CT with histopathologic step-section analysis. J Nucl Med 46(10):1642–1649

    PubMed  CAS  Google Scholar 

  • Franco G, De Nunzio C et al (2010) Ultrasound assessment of intravesical prostatic protrusion and detrusor wall thickness – new standards for noninvasive bladder outlet obstruction diagnosis? J Urol 183(6):2270–2274

    Article  PubMed  Google Scholar 

  • Futterer JJ, Engelbrecht MR et al (2007) Prostate cancer: comparison of local staging accuracy of pelvic phased-array coil alone versus integrated endorectal-pelvic phased-array coils. Local staging accuracy of prostate cancer using endorectal coil MR imaging. Eur Radiol 17(4):1055–1065

    Article  PubMed  Google Scholar 

  • Gibbs P, Tozer DJ et al (2001) Comparison of quantitative T2 mapping and diffusion-weighted imaging in the normal and pathologic prostate. Magn Reson Med 46(6):1054–1058

    Article  PubMed  CAS  Google Scholar 

  • Hacker A, Jeschke S et al (2006) Detection of pelvic lymph node metastases in patients with clinically localized prostate cancer: comparison of [18F]fluorocholine positron emission tomography-computerized tomography and laparoscopic radioisotope guided sentinel lymph node dissection. J Urol 176(5):2014–2018; discussion 2018–2019

    Article  PubMed  Google Scholar 

  • Haffner J, Potiron E et al (2009) Peripheral zone prostate cancers: location and intraprostatic patterns of spread at histopathology. Prostate 69(3):276–282

    Article  PubMed  Google Scholar 

  • Haider MA, van der Kwast TH et al (2007) Combined T2-weighted and diffusion-weighted MRI for localization of prostate cancer. AJR Am J Roentgenol 189(2):323–328

    Article  PubMed  Google Scholar 

  • Haider MA, Chung P et al (2008) Dynamic contrast-enhanced magnetic resonance imaging for localization of recurrent prostate cancer after external beam radiotherapy. Int J Radiat Oncol Biol Phys 70(2):425–430

    Article  PubMed  Google Scholar 

  • Hall WH, Jani AB et al (2005) The impact of age and comorbidity on survival outcomes and treatment patterns in prostate cancer. Prostate Cancer Prostatic Dis 8(1):22–30

    Article  PubMed  CAS  Google Scholar 

  • Halpern EJ, Verkh L et al (2000) Initial experience with contrast-enhanced sonography of the prostate. AJR Am J Roentgenol 174(6):1575–1580

    Article  PubMed  CAS  Google Scholar 

  • Heidenreich A, Bellmunt J et al (2011) EAU guidelines on prostate cancer. Part 1: screening, diagnosis, and treatment of clinically localised disease. Eur Urol 59(1):61–71

    Article  PubMed  Google Scholar 

  • Hovels AM, Heesakkers RA et al (2008) The diagnostic accuracy of CT and MRI in the staging of pelvic lymph nodes in patients with prostate cancer: a meta-analysis. Clin Radiol 63(4):387–395

    Article  PubMed  CAS  Google Scholar 

  • Huang Z, Haider MA et al (2006) Magnetic resonance imaging correlated with the histopathological effect of Pd-bacteriopheophorbide (Tookad) photodynamic therapy on the normal canine prostate gland. Lasers Surg Med 38(7):672–681

    Article  PubMed  Google Scholar 

  • Huisman HJ, Engelbrecht MR et al (2001) Accurate estimation of pharmacokinetic contrast-enhanced dynamic MRI parameters of the prostate. J Magn Reson Imaging 13(4):607–614

    Article  PubMed  CAS  Google Scholar 

  • Husarik DB, Miralbell R et al (2008) Evaluation of [(18)F]-choline PET/CT for staging and restaging of prostate cancer. Eur J Nucl Med Mol Imaging 35(2):253–263

    Article  PubMed  Google Scholar 

  • Jadvar H (2009) Molecular imaging of prostate cancer with 18F-fluorodeoxyglucose PET. Nat Rev Urol 6(6):317–323

    Article  PubMed  CAS  Google Scholar 

  • Jana S, Blaufox MD (2006) Nuclear medicine studies of the prostate, testes, and bladder. Semin Nucl Med 36(1):51–72

    Article  PubMed  Google Scholar 

  • Jemal A, Bray F et al (2011) Global cancer statistics. CA Cancer J Clin 61(2):69–90

    Article  PubMed  Google Scholar 

  • Jeon GS, Won JH et al (2009) The effect of transarterial prostate embolization in hormone-induced benign prostatic hyperplasia in dogs: a pilot study. J Vasc Interv Radiol 20(3):384–390

    Article  PubMed  Google Scholar 

  • Jia G, Heverhagen JT et al (2006) Pharmacokinetic parameters as a potential predictor of response to pharmacotherapy in benign prostatic hyperplasia: a preclinical trial using dynamic contrast-enhanced MRI. Magn Reson Imaging 24(6):721–725

    Article  PubMed  CAS  Google Scholar 

  • Kaplan SA, Hatzichristou D (2007) Open to debate. The motion: PDE5 inhibitors will have a significant role in the treatment of BPH. Eur Urol 52(5):1523–1527

    Article  PubMed  Google Scholar 

  • Kaplan SA, Te AE et al (1995) Transition zone index as a method of assessing benign prostatic hyperplasia: correlation with symptoms, urine flow and detrusor pressure. J Urol 154(5):1764–1769

    Article  PubMed  CAS  Google Scholar 

  • Keqin Z, Zhishun X et al (2007) Clinical significance of intravesical prostatic protrusion in patients with benign prostatic enlargement. Urology 70(6):1096–1099

    Article  PubMed  Google Scholar 

  • Kershaw LE, Hutchinson CE et al (2009) Benign prostatic hyperplasia: evaluation of T1, T2, and microvascular characteristics with T1-weighted dynamic contrast-enhanced MRI. J Magn Reson Imaging 29(3):641–648

    Article  PubMed  Google Scholar 

  • Koch WF, Ezz el Din K et al (1996) The outcome of renal ultrasound in the assessment of 556 consecutive patients with benign prostatic hyperplasia. J Urol 155(1):186–189

    Article  PubMed  CAS  Google Scholar 

  • Kojima M, Inui E et al (1997a) Noninvasive quantitative estimation of infravesical obstruction using ultrasonic measurement of bladder weight. J Urol 157(2):476–479

    Article  PubMed  CAS  Google Scholar 

  • Kojima M, Watanabe H et al (1997b) Preliminary results of power Doppler imaging in benign prostatic hyperplasia. Ultrasound Med Biol 23(9):1305–1309

    Article  PubMed  CAS  Google Scholar 

  • Lee F, Gray JM et al (1985) Transrectal ultrasound in the diagnosis of prostate cancer: location, echogenicity, histopathology, and staging. Prostate 7(2):117–129

    Article  PubMed  CAS  Google Scholar 

  • Leventis AK, Shariat SF et al (2001) Characteristics of normal prostate vascular anatomy as displayed by power Doppler. Prostate 46(4):281–288

    Article  PubMed  CAS  Google Scholar 

  • Linden RA, Halpern EJ (2007) Advances in transrectal ultrasound imaging of the prostate. Semin Ultrasound CT MR 28(4):249–257

    Article  PubMed  Google Scholar 

  • Liu JB, Merton DA et al (2006) Contrast enhanced ultrasound for radio frequency ablation of canine prostates: initial results. J Urol 176(4 Pt 1):1654–1660

    Article  PubMed  Google Scholar 

  • Mariappan P, Brown DJ et al (2007) Intravesical prostatic protrusion is better than prostate volume in predicting the outcome of trial without catheter in white men presenting with acute urinary retention: a prospective clinical study. J Urol 178(2):573–577; discussion 577

    Article  PubMed  Google Scholar 

  • Martorana G, Schiavina R et al (2006) 11C-choline positron emission tomography/computerized tomography for tumor localization of primary prostate cancer in comparison with 12-core biopsy. J Urol 176(3):954–960

    Article  PubMed  CAS  Google Scholar 

  • McConnell JD, Roehrborn CG et al (2003) The long-term effect of doxazosin, finasteride, and combination therapy on the clinical progression of benign prostatic hyperplasia. N Engl J Med 349(25):2387–2398

    Article  PubMed  CAS  Google Scholar 

  • McVary KT (2006) BPH: epidemiology and comorbidities. Am J Manag Care 12(5 Suppl):S122–S128

    PubMed  Google Scholar 

  • Mirza M, Griebling T (2011) Screening and management of prostate cancer in the elderly. Clin Geriatr 19(8):18–24

    Google Scholar 

  • Mitterberger MJ, Aigner F et al (2010) Comparative efficiency of contrast-enhanced colour Doppler ultrasound targeted versus systematic biopsy for prostate cancer detection. Eur Radiol 20(12):2791–2796

    Article  PubMed  Google Scholar 

  • Mulkern RV, Barnes AS et al (2006) Biexponential characterization of prostate tissue water diffusion decay curves over an extended b-factor range. Magn Reson Imaging 24(5):563–568

    Article  PubMed  Google Scholar 

  • Namasivayam S, Minhas S et al (1998) The evaluation of sexual function in men presenting with symptomatic benign prostatic hyperplasia. Br J Urol 82(6):842–846

    Article  PubMed  CAS  Google Scholar 

  • Oehr P, Bouchelouche K (2007) Imaging of prostate cancer. Curr Opin Oncol 19(3):259–264

    Article  PubMed  Google Scholar 

  • Oto A, Kayhan A et al (2010) Prostate cancer: differentiation of central gland cancer from benign prostatic hyperplasia by using diffusion-weighted and dynamic contrast-enhanced MR imaging. Radiology 257(3):715–723

    Article  PubMed  Google Scholar 

  • Pallwein L, Mitterberger M et al (2008) Ultrasound of prostate cancer: recent advances. Eur Radiol 18(4):707–715

    Article  PubMed  Google Scholar 

  • Pelzer A, Bektic J et al (2005) Prostate cancer detection in men with prostate specific antigen 4 to 10 ng/ml using a combined approach of contrast enhanced color Doppler targeted and systematic biopsy. J Urol 173(6):1926–1929

    Article  PubMed  Google Scholar 

  • Piert M, Park H et al (2009) Detection of aggressive primary prostate cancer with 11C-choline PET/CT using multimodality fusion techniques. J Nucl Med 50(10):1585–1593

    Article  PubMed  CAS  Google Scholar 

  • Pinggera GM, Mitterberger M et al (2008a) Alpha-Blockers improve chronic ischaemia of the lower urinary tract in patients with lower urinary tract symptoms. BJU Int 101(3):319–324

    Article  PubMed  CAS  Google Scholar 

  • Pinggera GM, Mitterberger M et al (2008b) Association of lower urinary tract symptoms and chronic ischaemia of the lower urinary tract in elderly women and men: assessment using colour Doppler ultrasonography. BJU Int 102(4):470–474

    Article  PubMed  Google Scholar 

  • Pisco JM, Pinheiro LC et al (2011) Prostatic arterial embolization to treat benign prostatic hyperplasia. J Vasc Interv Radiol 22(1):11–19; quiz 20

    Article  PubMed  Google Scholar 

  • Price DT, Coleman RE et al (2002) Comparison of [18F]fluorocholine and [18F]fluorodeoxyglucose for positron emission tomography of androgen dependent and androgen independent prostate cancer. J Urol 168(1):273–280

    Article  PubMed  Google Scholar 

  • Qayyum A, Coakley FV et al (2004) Organ-confined prostate cancer: effect of prior transrectal biopsy on endorectal MRI and MR spectroscopic imaging. AJR Am J Roentgenol 183(4):1079–1083

    Article  PubMed  Google Scholar 

  • Repetto L, Granetto C et al (1997) Comorbidity and cancer in the aged: the oncologists point of view. Rays 22(1 Suppl):17–19

    PubMed  CAS  Google Scholar 

  • Reske SN, Blumstein NM et al (2006) Imaging prostate cancer with 11C-choline PET/CT. J Nucl Med 47(8):1249–1254

    PubMed  CAS  Google Scholar 

  • Riches SF, Hawtin K et al (2009) Diffusion-weighted imaging of the prostate and rectal wall: comparison of biexponential and monoexponential modelled diffusion and associated perfusion coefficients. NMR Biomed 22(3):318–325

    Article  PubMed  CAS  Google Scholar 

  • Rigatti P, Suardi N et al (2011) Pelvic/retroperitoneal salvage lymph node dissection for patients treated with radical prostatectomy with biochemical recurrence and nodal recurrence detected by [11C]choline positron emission tomography/computed tomography. Eur Urol 60(5):935–943

    Article  PubMed  Google Scholar 

  • Rudoni M, Antonini G et al (1995) The clinical value of prostate-specific antigen and bone scintigraphy in the staging of patients with newly diagnosed, pathologically proven prostate cancer. Eur J Nucl Med 22(3):207–211

    Article  PubMed  CAS  Google Scholar 

  • Sala E, Eberhardt SC et al (2006) Endorectal MR imaging before salvage prostatectomy: tumor localization and staging. Radiology 238(1):176–183

    Article  PubMed  Google Scholar 

  • Sangar VK, Ragavan N et al (2005) The economic consequences of prostate and bladder cancer in the UK. BJU Int 95(1):59–63

    Article  PubMed  Google Scholar 

  • Savelli G, Maffioli L et al (2001) Bone scintigraphy and the added value of SPECT (single photon emission tomography) in detecting skeletal lesions. Q J Nucl Med 45(1):27–37

    PubMed  CAS  Google Scholar 

  • Scattoni V, Picchio M et al (2007a) Detection of lymph-node metastases with integrated [11C]choline PET/CT in patients with PSA failure after radical retropubic prostatectomy: results confirmed by open pelvic-retroperitoneal lymphadenectomy. Eur Urol 52(2):423–429

    Article  PubMed  Google Scholar 

  • Scattoni V, Zlotta A et al (2007b) Extended and saturation prostatic biopsy in the diagnosis and characterisation of prostate cancer: a critical analysis of the literature. Eur Urol 52(5):1309–1322

    Article  PubMed  Google Scholar 

  • Scheenen TW, Klomp DW et al (2004) Fast acquisition-weighted three-dimensional proton MR spectroscopic imaging of the human prostate. Magn Reson Med 52(1):80–88

    Article  PubMed  CAS  Google Scholar 

  • Schiavina R, Scattoni V et al (2008) 11C-choline positron emission tomography/computerized tomography for preoperative lymph-node staging in intermediate-risk and high-risk prostate cancer: comparison with clinical staging nomograms. Eur Urol 54(2):392–401

    Article  PubMed  Google Scholar 

  • Schmid DT, John H et al (2005) Fluorocholine PET/CT in patients with prostate cancer: initial experience. Radiology 235(2):623–628

    Article  PubMed  Google Scholar 

  • Sciarra A, Panebianco V et al (2010) Value of magnetic resonance spectroscopy imaging and dynamic contrast-enhanced imaging for detecting prostate cancer foci in men with prior negative biopsy. Clin Cancer Res 16(6):1875–1883

    Article  PubMed  CAS  Google Scholar 

  • Shimizu T, Nishie A et al (2009) Prostate cancer detection: the value of performing an MRI before a biopsy. Acta Radiol 50(9):1080–1088

    Article  PubMed  CAS  Google Scholar 

  • Shinmoto H, Oshio K et al (2009) Biexponential apparent diffusion coefficients in prostate cancer. Magn Reson Imaging 27(3):355–359

    Article  PubMed  Google Scholar 

  • Souvatzoglou M, Krause BJ et al (2011) Influence of (11)C-choline PET/CT on the treatment planning for salvage radiation therapy in patients with biochemical recurrence of prostate cancer. Radiother Oncol 99(2):193–200

    Article  PubMed  Google Scholar 

  • Stangelberger A, Waldert M et al (2008) Prostate cancer in elderly men. Rev Urol 10(2):111–119

    PubMed  Google Scholar 

  • Sun F, Sanchez FM et al (2008) Benign prostatic hyperplasia: transcatheter arterial embolization as potential treatment–preliminary study in pigs. Radiology 246(3):783–789

    Article  PubMed  Google Scholar 

  • Syrigos KN, Karapanagiotou E et al (2005) Prostate cancer in the elderly. Anticancer Res 25(6C):4527–4533

    PubMed  Google Scholar 

  • Tan YH, Foo KT (2003) Intravesical prostatic protrusion predicts the outcome of a trial without catheter following acute urine retention. J Urol 170(6 Pt 1):2339–2341

    Article  PubMed  Google Scholar 

  • Tan CH, Wang J et al (2011) Diffusion weighted imaging in prostate cancer. Eur Radiol 21(3):593–603

    Article  PubMed  Google Scholar 

  • Tanimoto A, Nakashima J et al (2007) Prostate cancer screening: the clinical value of diffusion-weighted imaging and dynamic MR imaging in combination with T2-weighted imaging. J Magn Reson Imaging 25(1):146–152

    Article  PubMed  Google Scholar 

  • Toi A, Neill MG et al (2007) The continuing importance of transrectal ultrasound identification of prostatic lesions. J Urol 177(2):516–520

    Article  PubMed  Google Scholar 

  • Tsuru N, Kurita Y et al (2005) Resistance index in benign prostatic hyperplasia using power Doppler imaging and clinical outcomes after transurethral vaporization of the prostate. Int J Urol 12(3):264–269; official journal of the Japanese Urological Association

    Article  PubMed  Google Scholar 

  • Turkbey B, Pinto PA et al (2009) Imaging techniques for prostate cancer: implications for focal therapy. Nat Rev Urol 6(4):191–203

    Article  PubMed  Google Scholar 

  • Valentino M, De Matteis M et al (2008) Contrast-enhanced US of the prostate with time/intensity curves: preliminary results. J Ultrasound 11(1):8–11

    Article  PubMed  CAS  Google Scholar 

  • van Waarde A, Jager PL et al (2006) Comparison of sigma-ligands and metabolic PET tracers for differentiating tumor from inflammation. J Nucl Med 47(1):150–154

    PubMed  Google Scholar 

  • Villeirs GM, Oosterlinck W et al (2010) A qualitative approach to combined magnetic resonance imaging and spectroscopy in the diagnosis of prostate cancer. Eur J Radiol 73(2):352–356

    Article  PubMed  Google Scholar 

  • Walter LC, Bertenthal D et al (2006) PSA screening among elderly men with limited life expectancies. JAMA 296(19):2336–2342

    Article  PubMed  CAS  Google Scholar 

  • Walz J, Marcy M et al (2011) Identification of the prostate cancer index lesion by real-time elastography: considerations for focal therapy of prostate cancer. World J Urol 29(5):589–594

    Article  PubMed  Google Scholar 

  • Watanabe H (1998) New concept of BPH: PCAR theory. Prostate 37(2):116–125

    Article  PubMed  CAS  Google Scholar 

  • Wilkinson AG, Wild SR (1992) Is pre-operative imaging of the urinary tract worthwhile in the assessment of prostatism? Br J Urol 70(1):53–57

    Article  PubMed  CAS  Google Scholar 

  • Yoshizako T, Wada A et al (2008) Usefulness of diffusion-weighted imaging and dynamic contrast-enhanced magnetic resonance imaging in the diagnosis of prostate transition-zone cancer. Acta Radiol 49(10):1207–1213

    Article  PubMed  CAS  Google Scholar 

  • Zakian KL, Shukla-Dave A et al (2008) 1H magnetic resonance spectroscopy of prostate cancer: biomarkers for tumor characterization. Cancer Biomark 4(4–5):263–276

    PubMed  CAS  Google Scholar 

  • Zhu Y, Chen Y et al (2010) Contrast-enhanced harmonic ultrasonography for the assessment of prostate cancer aggressiveness: a preliminary study. Korean J Radiol 11(1):75–83

    Article  PubMed  Google Scholar 

  • Zhu X, Albertsen PC et al (2012) Risk-based prostate ­cancer screening. Eur Urol 61(4):652–661

    Article  PubMed  Google Scholar 

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Valentino, M. et al. (2013). Benign Prostate Hyperplasia and Prostatic Tumor. In: Guglielmi, G., Peh, W., Guermazi, A. (eds) Geriatric Imaging. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-35579-0_32

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