Skip to main content

The International Diffusion of Biotechnology: the Arrival of Developing Countries

  • Chapter
  • First Online:
Book cover Long Term Economic Development

Part of the book series: Economic Complexity and Evolution ((ECAE))

  • 1550 Accesses

Abstract

According to conventional economic theory, countries tend to converge in economic and technological terms towards the leader. More recently, empirical approaches by economic historians (Abramovitz, Landes, Madison, Reinert) have found that while some countries are catching up, others are falling increasingly behind. Several theories compete to explain the precise mechanisms that explain how technological diffusion takes place. The paper reviews them and draws testable hypotheses for the study of international biotechnology diffusion. Biotechnologies are one of the leading sets of technologies developed in the late 20th century. They encompass applications in agriculture, chemicals, environment and pharmaceuticals. The United States has led the way in both scientific and industrial development of biotechnologies and these have quickly spread to Canada, Japan and Western Europe. Are the main developing countries adopting biotechnology? A study of the adoption of human health biotechnology in eight developing countries in Asia (China, India, Korea, and Singapore) and Latin America (Argentina, Brazil, Chile and Mexico) was conducted, based on the analysis of in situ interviews, patents and scientific publication. The study shows a marked process of adoption and learning in science: each of the above-mentioned developing countries is increasing its share of world publication between 1996 and 2008. However, their share of biotechnology patents for the same period has barely increased. There are also regional differences in terms of sectoral concentration; Latin America, Argentina and Brazil are eager adopters of agricultural biotechnology and are moving up in the pharmaceutical records. Several Argentinean, Chinese, Indian, and South Korean pharmaceutical companies have been particularly active in the development of biogenerics.

Reprinted from Journal of Evolutionary Economics 22(4), 767-783 , Springer (2012)

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Notes

  1. 1.

    Science-Metrix used the Scopus database; through a computerized search 10,160 journals were analysed, and a list of keywords found in the title, keywords and abstract of articles. Un article co-authored by scientists from different countries counts as many times as there are co-authors. I.e. An article written by an Australian, a Chinese and a Japanese scholar, appears once for Australia, once for China, and once for Japan. Such article will represent one international collaboration for each country. The distribution was highly skewed: some 1207 of these journals had 80 % of the articles.

  2. 2.

    Venture capital in China is still less developed than in industrial countries but it has been growing fast. The VC funds almost doubled from 2006 to 2007, an important share of funding came from abroad. As of 2007, the VC investment in China was US$ 3.25 Billion compared to US$30 billion in the U.S.. About 13 % of VC was invested in bio/health care in China, still less but not by so much than in the U.S. (China Biotech, 2009).

    The government of all levels (state, province and cities) are among the principal sources of venture capital. In contrast to the U.S. VC, which brings not only money but also expertise, the lack of business expertise is reducing the effectiveness of government venture capital. In 2007 appeared the first local biotechnology fund (22 local biotech firms) and several multinational VC funds (BioVeda China, 2005).

References

  • Abramovitz M (1986) Catching up, forging ahead, and falling behind. J Econ Hist 46(2):385–406

    Article  Google Scholar 

  • Barro RJ (1991) Economic growth in a cross section of countries. Q J Econ 106(2):407–443

    Article  Google Scholar 

  • Bernard AB, Jones CI (1996) Comparing apples to oranges: productivity convergence and measurement across industries and countries. Am Econ Rev 86(5):1216–1238

    Google Scholar 

  • Caselli F, Coleman WJ (2001) Cross-country technology diffusion: the case of computers. Am Econ Rev 91(2):328–335

    Article  Google Scholar 

  • Cohen W, Levinthal DA (1989) Innovation and Learning: the two faces of R&D. Econ J 99:569–596

    Article  Google Scholar 

  • Cohen W, Levinthal DA (1990) Absorptive capacity: a new perspective on learning and innovation. Adm Sci Q 35(1):128–152

    Article  Google Scholar 

  • Comin D, Hobijn B (2004) Cross-country technology adoption: making the theories face the facts. J Monet Econ 51:39–83

    Article  Google Scholar 

  • David P, Arthur WB (1985) Clio and the economics of QWERTY. Am Econ Rev 75(2):332–337

    Google Scholar 

  • Davies S (1979) The diffusion of process innovations. Cambridge University Press, Cambridge

    Google Scholar 

  • Feldman M (1994) The geography of innovation. Kluwer, Boston

    Book  Google Scholar 

  • Feldman M, Audretsch D (1999) Innovation in cities: science-based diversity, specialisation and localized competition. Eur Econ Rev 43:409–429

    Article  Google Scholar 

  • Frew S, Rezaie R, Sammut SM, Ray M, Daar AS, Singer P (2007) India’s health biotechnology at a crossroads. Nat Biotechnol 25(4):403–418

    Article  Google Scholar 

  • Griliches Z (1957) Hybrid corn: an exploration on the economic of technological change. Econometrica 25(4):501–522

    Article  Google Scholar 

  • Hagerstrand T (1953) Innovation diffusion as a spatial process. University of Chicago Press, Chicago (1967 Edition)

    Google Scholar 

  • Inklaar R, Timmer M (2009) Productivity convergence across industries and countries: the importance of theory-based measurement. Macroecon Dyn 13:218–240

    Article  Google Scholar 

  • Keller W (2004) International technology diffusion. J Econ Lit 42(3):752–783

    Article  Google Scholar 

  • Klepper S (1997) Industry life cycles. Ind Corp Change 6(1):145–138

    Article  Google Scholar 

  • Landes D (1999) The wealth and poverty of nations. Norton, New York

    Google Scholar 

  • Lee K, Lim C (2001) Technological regimes, catching up and leapfrogging: findings from the Korean industries. Res Policy 30(3):459–483

    Article  Google Scholar 

  • Lundvall B-A (1992) National systems of innovation. Pinter, London

    Google Scholar 

  • Maddison A (2007) Contours of the World Economy, 1-2003. Oxford University Press, New York

    Google Scholar 

  • Malerba F (ed) (2004) Sectoral systems of innovation. Cambridge University Press, Cambridge

    Google Scholar 

  • McWilliams B, Zilberman D (1996) Time of technology adoption and learning by using. Econ Innov New Technol 4(2):139–154

    Article  Google Scholar 

  • Meade PT, Rabello L (2004) The technology adoption life cycle attractor: understanding the dynamics of high-technology markets. Technol Forecast Soc Change 71:667–684

    Article  Google Scholar 

  • Mercurio BC (2004) TRIPs, patents and access to life-saving drugs in the developing world. Marquette Intellect Prop Law Rev 8(2):211–253

    Google Scholar 

  • Nelson R (ed) (1993) National innovation systems. Oxford University Press, New York and Oxford

    Google Scholar 

  • Perez C, Soete L (1988) Catching up in technology: entry barriers and windows of opportunity. In: Dosi G, Freeman C, Nelson R, Silverberg G (eds) Technical change and economic theory. Pinter, London, pp 458–480

    Google Scholar 

  • Reinert E (2007) Why some countries grow rich, and why poor countries stay poor. Perseus, New York

    Google Scholar 

  • Rogers E (1995) Diffusion of innovations, 4th edn. Free Press, N. York

    Google Scholar 

  • Ryan B, Gross NC (1943) The diffusion on hybrid seed corn in two Iowa communities. Rural Sociol 8:15–24

    Google Scholar 

  • Stoneman P (2002) The economics of technological diffusion. Blackwell, Maiden MA

    Google Scholar 

  • Tassey G (1997) The economics of R&D policy. Quorum Books, Westport, CT

    Google Scholar 

  • Tassey G (2007) The technology imperative. Elgar, Cheltenham

    Google Scholar 

  • UNESCOQuach U, Thorsteindottir H, Singer PA, Daar AS (2010) Science Report 2010, Paris

    Google Scholar 

  • Vernon R (1966) International investment and international trade in the product life cycle. Q J Econ 80:190–207

    Article  Google Scholar 

  • Wong J, Quach U, Thorsteindottir H, Singer PA, Daar AS (2004) South Korean Biotechnology: a rising industrial and scientific powerhouse. Nat Biotechnol 22:42–44

    Article  Google Scholar 

  • Zhu K, Kraemer KL, Xu S (2006) The process of innovation assimilation in different countries. Manage Sci 52(10):1557–1576

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Jorge Niosi .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2013 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Niosi, J., Hanel, P., Reid, S. (2013). The International Diffusion of Biotechnology: the Arrival of Developing Countries. In: Pyka, A., Andersen, E. (eds) Long Term Economic Development. Economic Complexity and Evolution. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-35125-9_10

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-35125-9_10

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-35124-2

  • Online ISBN: 978-3-642-35125-9

  • eBook Packages: Business and EconomicsEconomics and Finance (R0)

Publish with us

Policies and ethics