Special Ancillary Techniques: Immunohistochemistry

  • Gary Tse
  • Puay Hoon Tan
  • Fernando Schmitt


The role of immunohistochemistry in the assessment of breast lesions, in particular breast cancers, cannot be overemphasized. Currently, there is a whole gamut of markers that are being used, aiding in the differentiation between benign and malignant breast lesions, prognostication of breast cancers, and prediction of responses to therapy. While most of the routine immunohistochemistry studies are being done on the paraffin-embedded histologic samples using either the resection specimen or the preoperative biopsy, the use of cytologic preparations in immunohistochemistry is gaining popularity and experience.


Breast Cancer Breast Lesion Myoepithelial Cell Lobular Carcinoma Invasive Lobular Carcinoma 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • Gary Tse
    • 1
  • Puay Hoon Tan
    • 2
  • Fernando Schmitt
    • 3
  1. 1.Prince of Wales Hospital Department of Anatomical And Cellular PathologyThe Chinese University of Hong KongShatin, NTHong Kong SAR
  2. 2.Department of PathologySingapore General HospitalSingaporeSingapore
  3. 3.Department of Pathology and OncologyMedical Faculty of Porto University and IPATIMUPPortoPortugal

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