Models of Tet-On System with Epigenetic Effects

  • Russ Harmer
  • Jean Krivine
  • Élise Laruelle
  • Cédric Lhoussaine
  • Guillaume Madelaine
  • Mirabelle Nebut
Part of the Lecture Notes in Computer Science book series (LNCS, volume 7605)

Abstract

We present the first results of ongoing work investigating two models of the artificial inducible promoter Tet-On that include epigenetic regulation. We consider chromatin states and 1D diffusion of transcription factors that reveal, respectively, stochastic noise and a memory effect.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Russ Harmer
    • 1
  • Jean Krivine
    • 1
  • Élise Laruelle
    • 1
  • Cédric Lhoussaine
    • 2
  • Guillaume Madelaine
    • 2
    • 3
  • Mirabelle Nebut
    • 2
  1. 1.PPS (CNRS UMR 7126)University Paris DiderotFrance
  2. 2.LIFL (CNRS UMR 8022)University of Lille 1France
  3. 3.ÉNS CachanFrance

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