A Numerical Model of Metastatic Colon Cancer

Abstract

Mathematical models of tumor growth have become an important approach to understanding tumor biology. To date, such models have been applied to only a few tumor types. The goal of this study is to apply a tumor model to liver metastases, to understand if the model is useful for this very common, clinically important type of tumor. CT scan and MRI scan tumor growth data will be extracted from routine imaging studies, examining tumor size in patients who received no treatment as well as those who were treated with a variety of modalities. Calculations of tumor growth velocity, diffusion and proliferation will be calculated. These parameters will then be correlated with survival data.