Abstract
Carbonylative transition metal catalysis has since the pioneering work performed by Heck and coworkers in the early 1970s evolved into a highly attractive strategy for the incorporation of the carbonyl unit using mild reaction conditions [1, 2]. The introduction of the highly versatile CO moiety not only elongates the expanding molecule with a one carbon fragment, but may also serve as a flexible platform for further manipulations of the molecule displaying numerous applications. Otherwise, the carbonyl entity may also act as a valuable motif in itself and is found in a vast number of bioactive compounds.
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Schoenberg A, Bartoletti I, Heck RF (1974) J Org Chem 39:3318
Grigg R, Mutton SP (2010) Tetrahedron 66:5515
Brennführer A, Neumann H, Beller M (2009) Angew Chem Int Ed 48:4114
Wu X-F, Jiao H, Neumann H, Beller M (2011) ChemCatChem 3:726
Munday RH, Martinelli JR, Buchwald SL (2008) J Am Chem Soc 130:2754
Arthuis M, Lecup A, Roulland E (2010) Chem Commun 46:7810
Kolla L (ed) (2008) Modern carbonylation methods. Wiley and Sons, Germany
Roberts B, Liptrot D, Alcaraz L, Luker T, Stocks M (2010) J Org Lett 12:4280
Wu X, Wannberg J, Larhed M (2006) Tetrahedron 62:4665
Amatore C, Jutand A (2000) Acc Chem Res 33:314
Carrow BP, Hartwig JF (2010) J Am Chem Soc 132:79
Henriksen ST, Norrby P-O, Kaukoranta P, Andersson PG (2008) J Am Chem Soc 130:10414
Satoh T, Itaya T, Okuro K, Miura M, Nomura M (1995) J Org Chem 60:7267
Wu X-F, Neumann H, Beller M (2010) Angew Chem Int Ed 49:5284
Wu X-F, Jiao H, Neumann H, Beller M (2011) ChemCatChem 3:726
Wu X-F, Neumann H, Spannenberg A, Schulz T, Jiao H, Beller M (2010) J Am Chem Soc 132:14596
Martinelli JR, Watson DA, Freckmann DMM, Barder TE, Buchwald SL (2008) J Org Chem 73:7102
Fujita T, Nakano K, Yamashita M, Nozaki K (2006) J Am Chem Soc 128:1968
Gaviño R, Pellegrini S, Castanet Y, Mortreux A, Mentré O (2001) App Catal A General 217:91
Sergeev AG, Spannenberg A, Beller M (2008) J Am Chem Soc 130:15549
Hermange P, Lindhardt AT, Taaning RH, Bjerglund K, Lupp D, Skrydstrup T (2011) J Am Chem Soc 133:6061
Gauthier D, Lindhardt AT, Olsen EPK, Overgaard J, Skrydstrup T (2010) J Am Chem Soc 132:7998
Martins A, Candito DA, Lautens M (2010) Org Lett 12:5186
Klaus S, Neumann H, Zapf A, Strübing D, Hübner S, Almena J, Riermeier T, Gross P, Sarich M, Krahnert W-R, Rossen K, Beller M (2006) Angew Chem Int Ed 45:154
Ishiyama T, Kizaki H, Hayashi T, Suzuki A, Miyaura N (1998) J Org Chem 63:4726
Garrou PE, Heck RF (1976) J Am Chem Soc 98:4115
Cao P, Sun Y, Gu R (2004) J Phys Chem B 108:4716
Veleckis E, Hacker DS (1984) J Chem Eng Data 29:36
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© 2012 Springer-Verlag Berlin Heidelberg
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Gøgsig, T.M. (2012). Carbonylative Heck Reaction. In: New Discoveries on the β-Hydride Elimination. Springer Theses. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-32099-6_7
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DOI: https://doi.org/10.1007/978-3-642-32099-6_7
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