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Combined T and B Cell Immunodeficiencies

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Clinical Cases in Primary Immunodeficiency Diseases

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Abstract

The immune system is divided into humoral and cellular mechanisms. B cells are known for their role in humoral immunity by secreting antibodies against various pathogens, and T cells are responsible for cell-mediated immunity by killing intracellular organisms. T cells are also necessary in the maturation of B cells into antibody secreting plasma cells.

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Author information

Authors and Affiliations

  1. Division of Immunology, Boston Children’s Hospital, Boston, MA, USA

    Francisco A. Bonilla M.D., Ph.D.

  2. Department of Pediatrics, Harvard Medical School, Boston, MA, USA

    Francisco A. Bonilla M.D., Ph.D.

  3. Division of Pediatric Allergy/Immunology, Marmara University, Istanbul, Turkey

    Isil B. Barlan M.D. & Elif Aydiner M.D.

  4. Department of Pediatrics, Kuwait University, Kuwait, Kuwait

    Waleed Al-Herz M.D.

  5. Department of Pediatrics, Immunological Outpatient Clinic,Biomedical Research Institute, Vienna, Austria

    Martha M. Eibl M.D. & Hermann M. Wolf M.D.

  6. Department of Immunology and Immunodeficiencies, School of Medicine, University Hospital Vall d’Hebron, Barcelona, Spain

    Teresa Espanol M.D., Ph.D.

  7. Pediatric Infectious Diseases and Immunodeficiencies Unit, Vall d’Hebron University Hospital, Barcelona, Spain

    Andrea Martín M.D. & Pere Soler-Palacín M.D., Ph.D.

  8. Department of Infectious and Pediatric Immunology, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary

    László Maródi M.D., Ph.D., D.Sc

  9. Department of Pediatrics, Research Center for Immunodeficiencies, Children’s Medical Center Hospital, Tehran University of Medical Sciences, Tehran, Iran

    Shabnam Pourhamdi M.D.

  10. Division of Clinical Immunology and Allergy, Research Center for Immunodeficiencies, Children’s Medical Center Hospital, Tehran University of Medical Sciences, Tehran, Iran

    Asghar Aghamohammadi M.D., Ph.D.

Authors
  1. Francisco A. Bonilla M.D., Ph.D.
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  2. Isil B. Barlan M.D.
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  3. Elif Aydiner M.D.
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  4. Waleed Al-Herz M.D.
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  5. Martha M. Eibl M.D.
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  6. Teresa Espanol M.D., Ph.D.
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  7. Andrea Martín M.D.
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  8. László Maródi M.D., Ph.D., D.Sc
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  9. Shabnam Pourhamdi M.D.
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  10. Pere Soler-Palacín M.D., Ph.D.
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  11. Hermann M. Wolf M.D.
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  12. Asghar Aghamohammadi M.D., Ph.D.
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Editor information

Editors and Affiliations

  1. Research Center for Immunodeficiencies, Children's Medical Center Hospital, Tehran University of Medical Sciences, Qarib St, Keshavarz Blvd, Tehran, 14194, Iran

    Asghar Aghamohammadi

  2. Research Center for Immunodeficiencies, Children's Medical Center Hospital, Tehran University of Medical Sciences, Qarib St, Keshavarz Blvd, Tehran, 14194, Iran

    Nima Rezaei

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© 2012 Springer-Verlag Berlin Heidelberg

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Bonilla, F.A. et al. (2012). Combined T and B Cell Immunodeficiencies. In: Aghamohammadi, A., Rezaei, N. (eds) Clinical Cases in Primary Immunodeficiency Diseases. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-31785-9_2

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