• Hart IsaacsJr


The leukemias are a heterogeneous group of hematologic neoplasms characterized by the infiltration of abnormal hematopoietic cells in the bone marrow, peripheral blood, and various organs and tissues. Following this clonal overgrowth of leukemic cells, the patient eventually develops hematologic sequelae of bone marrow failure manifested by anemia, neutropenia, and thrombocytopenia [1, 2].


Acute Myeloid Leukemia Acute Lymphocytic Leukemia Down Syndrome Klinefelter Syndrome Extramedullary Hematopoiesis 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • Hart IsaacsJr
    • 1
  1. 1.Department of Pathology Rady Childrens Hospital San DiegoUniversity of California San Diego School of MedicineSan DiegoUSA

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