Clinical Orthodontic Research

  • Kevin O’Brien


One of the great buzz phrases over the last few years is evidenced-based care. However, while this is easy to promote as a concept, we have to carry out the research that is going to provide us with the evidence that will either reinforce or make us change the care that we provide. At this point it is relevant for us to consider the type of investigation or research that is going to give the highest level of evidence, and this is always the randomized controlled trial or systematic review. All other types of study, such as case report, retrospective study, or comparison of case series, do not give us adequate information. As a result, I will confine this chapter to a description of how to carry out a randomized controlled trial.


Orthodontic Treatment Facial Growth Space Closure Mandibular Length Functional Appliance 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


These two books provide excellent and detailed overviews of randomized controlled trials:

  1. 1.
    Jadad A (1998) Randomised controlled trials: a users guide. BMJ Books, LondonGoogle Scholar
  2. 2.
    Friedman LM, Furberg CD, DeMets DL (1998) Fundamentals of clinical trials. Springer, New YorkGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  1. 1.School of Dentistry, The University of ManchesterManchesterUK

Personalised recommendations