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Benign, Degenerative and Inflammatory Diseases

  • A. J. Beer
  • O. Ratib
  • I. Dregely
  • M. Eiber
  • M. Essler
  • S. Foerster
  • S. Nekolla
  • C. Rischpler
  • J.-P. Willi
  • I. Yakushev
Chapter

Abstract

18F-FDG PET studies were shown to be quite sensitive to inflammation as well to a variety of benign diseases that induce focal increase in metabolism [1–3]. While in most countries PET imaging of these diseases are not reimbursed, it remains a potential alternative imaging modality for selected cases. FDG-PET remains a sensitive diagnostic modality for detection of infectious diseases and exploring sources of fever of unknown origin. In this chapter several diseases are presented, but also examples of identification and characterization of vascular plaques [4]. While 18F-FDG is being reported as a potential marker of plaque inflammatory process and therefore may help identify unstable plaques and be a predictor of cardiovascular events, alternative PET tracers are also being evaluated for better characterization of vascular plaques [4–6]. Another application domain of PET and therefore could potentially benefit from hybrid PET-MR is the assessment of neurodegenerative diseases and differentiation of diagnostic classification based on anatomical distribution of brain metabolic activity.

Keywords

Cardiac Sarcoidosis Posterior Cortical Atrophy Neurodegenerative Dementia Vascular Plaque Brain Metabolic Activity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • A. J. Beer
    • 1
  • O. Ratib
    • 2
  • I. Dregely
    • 3
  • M. Eiber
    • 1
  • M. Essler
    • 3
  • S. Foerster
    • 3
  • S. Nekolla
    • 3
  • C. Rischpler
    • 3
  • J.-P. Willi
    • 2
  • I. Yakushev
    • 3
  1. 1.Department of Radiology, Klinikum Rechts der IsarTechnische Universität MünchenMunichGermany
  2. 2.Division of Nuclear Medicine and Molecular Imaging, Department of Medical ImagingGeneva University HospitalsGenevaSwitzerland
  3. 3.Department of Nuclear MedicineTechnische Universität MünchenMunichGermany

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