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A Calibration Approach for Single-Energy X-ray Absorptiometry Method to Provide Absolute Breast Tissue Composition Accuracy for the Long Term

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Breast Imaging (IWDM 2012)

Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 7361))

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Abstract

We report on development of a new calibration approach for the Single-Energy X-ray Absorptiometry method (SXA) to provide absolute breast tissue composition accuracy in clinical conditions for the long term and realize cross-calibration between machines, sites and manufacturers.

The proposed method takes into account both geometric and image related factors that impact the calibration of grayscale image into absolute tissue composition. A specially designed phantom (GEN III) is imaged in place of the breast and analyzed as if it were a breast. An automatic algorithm was developed to extract all necessary parameters for recalibration. Subsequently, the thickness correction factors and recalibration procedures were applied during calculations of density.

A breakpoint stepwise approach was used to correct the thickness variations. It provides the thickness measurement variations over time with a typical standard deviation of 0.2-0.3 mm. After recalibration, the recalculated %FGV of the GEN III region of interests are consistent over time, with a typical standard deviation around 1%.

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© 2012 Springer-Verlag Berlin Heidelberg

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Malkov, S., Wang, J., Duewer, F., Shepherd, J.A. (2012). A Calibration Approach for Single-Energy X-ray Absorptiometry Method to Provide Absolute Breast Tissue Composition Accuracy for the Long Term. In: Maidment, A.D.A., Bakic, P.R., Gavenonis, S. (eds) Breast Imaging. IWDM 2012. Lecture Notes in Computer Science, vol 7361. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-31271-7_99

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  • DOI: https://doi.org/10.1007/978-3-642-31271-7_99

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-31270-0

  • Online ISBN: 978-3-642-31271-7

  • eBook Packages: Computer ScienceComputer Science (R0)

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