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Cryptorchidism, Empty Scrotum

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Abstract

Cryptorchidism is a frequent disorder: 2–5 % of the neonates born at term and about 20 % of those with a birth weight <2,500 g have cryptorchidism (i.e., bilateral altogether in 45 %), and still 1 % at the age of 1 year and somewhat less after the end of growth. Recently, the prevalence of cryptorchidism is increasing in some developed countries. Its clinical significance is many and diverse:

  • Possible impairment of fertility (reduced germ cell number at birth or general depletion of germ and to a lesser degree of Leydig cells after birth and specifically loss from 6 months to 4 years of age [due to maternal lifestyle or exposition to diethylstilbestrol and factors related to failing descent]).

  • Increased risk of testicular malignancy (2.75–8 times increased risk of neoplasm for the undescended testis).

  • Pathologies which become visible and palpable in descended testes, for example, testicular torsion # or tumor, may be hidden.

  • Psychological effect on the developed young man is possible.

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Bibliography

General: Occurrence, Clinical Skills, Differential Diagnosis

  • Boisen KA, Kaleva M, Main KM et al (2004) Difference in prevalence of congenital cryptorchidism in infants between two Nordic countries. Lancet 363:1264–1269

    Article  PubMed  CAS  Google Scholar 

  • Chipkevitch E, Nishimura RT, Tu DG, Galea-Rojas M (1996) Clinical measurement of testicular volume in adolescents: comparison of the reliability of 5 methods. J Urol 156:2050–2053

    Article  PubMed  CAS  Google Scholar 

  • Hutson JM (1998) Undescended testis, torsion, and varicocele. In: O’Neill JA Jr et al (eds) Pediatric surgery, vol II, 5th edn. Mosby, St Louis

    Google Scholar 

  • Hutson JM, Balic A, Nation T, Southwell B (2010) Cryptorchidism. Semin Pediatr Surg 19:215–224

    Article  PubMed  Google Scholar 

Section 31.1

  • Berkowitz GS, Lapinski RH, Dolgin SE, Gazella JG, Bodian CA, Holzman IR (1993) Prevalence and natural history of cryptorchidism. Pediatrics 92:44–49

    PubMed  CAS  Google Scholar 

  • Hussain Taqvi SR, Akhtar J, Batool T, Tabassum R, Mirza F (2006) Correlation of the size of undescended testis with its location in various age groups. J Coll Physicians Surg Pak 16:594–597

    PubMed  Google Scholar 

  • La Scala GC, Ein SH (2004) Retractile testes: an outcome analysis on 150 patients. J Pediatr Surg 39:1014–1017

    Article  PubMed  Google Scholar 

  • Wenzler DL, Bloom DA, Park JM (2004) What is the rate of spontaneous testicular descent in infants with cryptorchidism? J Urol 171:849–851

    Article  PubMed  Google Scholar 

Section 31.2

  • Merjer RW, Hack WW, van der Voort-Doedens LM, Haasnoot K, Bos SD (2004) Surgical findings in acquired undescended testis. J Pediatr Surg 39:1242–1244

    Article  Google Scholar 

  • Yoshida T, Ohno K, Morotomi Y, Nakamura T, Azuma T, Yamada H, Hayashi H, Suehiro S (2009) Clinical and pathological features of ascending testis. Osaka City Med J 55:81–87

    PubMed  Google Scholar 

  • Zenaty D, Dijoud F, Morel Y, Cabrol S, Mouriquand P, Nicolino M, Bouvatier C, Pinto G, Lecointre C, Pienkowski C, Soskin S, Bost M, Bertrand AM, El-Ghoneimi A, Nihoul-Fekete C, Léeger J (2006) Bilateral anorchia in infancy: occurrence of micropenis and the effect of testosterone treatment. J Pediatr 149:687–691

    Article  PubMed  CAS  Google Scholar 

Sections 31.3–31.4

  • Abbasoglu L, Salman FT, Gün F, Asicioglu C (2004) Polyorchidism presenting with undescended testis. Eur J Pediatr Surg 14:355–357

    Article  PubMed  CAS  Google Scholar 

  • Koff WJ, Scaletscky R (1990) Malformations of the epididymis in undescended testis. J Urol 143:340–433

    PubMed  CAS  Google Scholar 

  • Savas M, Yeni E, Ciftci H, Cece H, Topal U, Utangac MM (2010) Polyorchidism: a three-case report and review of the literature. Andrologia 42:57–61

    Article  PubMed  CAS  Google Scholar 

  • Wakeman D, Warner BW (2010) Urogenital nonunion – a rare anomaly associated with the undescended testis. Am J Surg 199:e59–e60

    Article  PubMed  Google Scholar 

Section 31.5

  • Biers SM, Malone PS (2010) A critical appraisal of the evidence for improved fertility indices in undescended testes after gonadotropin-releasing hormone therapy and orchidopexy. J Pediatr Urol 6:239–246

    Article  PubMed  CAS  Google Scholar 

  • Bukowski TP, Wacksman J, Billmire DA et al (1995) Testicular autotransplantation: a 17-year review of an effective approach to the management of the intra-abdominal testis. J Urol 154:558–561

    Article  PubMed  CAS  Google Scholar 

  • Daher P, Nabbout P, Feghali J, Riachi E (2009) Is the Fowler-Stephens procedure still indicated for the treatment of nonpalpable intraabdominal testis? J Pediatr Surg 44:1999–2003

    Article  PubMed  Google Scholar 

  • De Schepper J, Belva F, Schiettecatte J, Anckaert E, Tournaye H, Bonduelle M (2009) Testicular growth and tubular function in prepubertal boys conceived by intracytoplasmic sperm injection. Horm Res 71:359–363

    Article  PubMed  Google Scholar 

  • Gapany C, Frey P, Cachat F, Gudinchet F, Jichlinski P, Meyrat BJ, Ramseyer P, Theintz P, Burnand B (2008) Management of cryptorchidism in children: guidelines. Swiss Med Wkly 138:492–498

    PubMed  Google Scholar 

  • Esposito C, De Lucia A, Palmieri A, Centonze A, Damiano R, Savanelli A, Valerio G, Settimi A (2003) Comparison of five different hormonal treatment protocols for children with cryptorchidism. Scand J Urol Nephrol 37:246–249

    Article  PubMed  CAS  Google Scholar 

  • Gordon M, Cervellioni RM, Morabito A, Bianchi A (2010) 20 years of transscrotal orchidopexy for undescended testis: results and outcomes. J Pediatr Urol 6:506–512

    Article  PubMed  Google Scholar 

  • Kjaer S, Mikines KJ (2006) HCG in the treatment of cryptorchidism. The effect of age and position of the testis. Ugeskr Laeger 168:1448–1451

    PubMed  Google Scholar 

  • Kollin C, Hesser U, Ritzen EM, Karpe B (2006) Testicular growth from birth to two years of age, and effect of orchidopexy at age nine months: a randomized, controlled study. Acta Paediatr 95:318–324

    Article  PubMed  Google Scholar 

  • Ludwig AK, Katalinic A, Thyen U, Sutcliffe AG, Dietrich K, Ludwig M (2009) Physical health at 5.5 years of age of term-born singletons after intracytoplasmic sperm injection: results of prospective, controlled, single-blinded study. Fertil Steril 91:115–124

    Article  PubMed  Google Scholar 

  • Marcelli F, Robin G, Lefebvre-Khalil V, Marchetti C, Lemaitre L, Mitchell V, Rigot JM (2008) Results of surgical testicular sperm extractions [TESE] in a population of azoospermic patients with a history of cryptorchidism based on a 10-year experience of 142 patients. Prog Urol 18:657–662

    Article  PubMed  CAS  Google Scholar 

  • McAlleer IM et al (1995) Fertility index analysis in cryptorchidism. J Urol 153:1255

    Article  Google Scholar 

  • Miller KD, Coughlin MT, Lee PA (2001) Fertility after unilateral cryptorchidism. Paternity, time to conception, pretreatment testicular location and size, hormone and sperm parameters. Horm Res 55:249–253

    Article  PubMed  CAS  Google Scholar 

  • Moller H, Cortes D, Engholm G, Thorup J (1998) Risk of testicular cancer with cryptorchidism and with testicular biopsy: cohort study. BMJ 317(7160):729

    Article  PubMed  CAS  Google Scholar 

  • Nouira F, Ben Ahmed Y, Jlidi S, Sarrai N, Chariag A, Ghorbel S, Khemakhem R, Chaouachi B (2011) Management of perineal ectopic testes. Tunis Med 89:47–49

    PubMed  Google Scholar 

  • Puri P, O’Donnell B (1988) Semen analysis of patients who had orchidopexy at or after seven years of age. Lancet II:1051–1052

    Article  Google Scholar 

  • Schindler AM, Diaz P, Cuendet A, Sizonenko PC (1987) Cryptorchidism: a morphological study of 670 biopsies. Helv Paediatr Acta 42:145–158

    PubMed  CAS  Google Scholar 

  • Stec AA, Tanaka ST, Adams MC, Pope JC 4th, Thomas JC, Brock HW 3rd (2009) Orchidopexy for intra-abdominal testes: factors predicting success. J Urol 182:1917–1920

    Article  PubMed  Google Scholar 

  • Thorup J, Jensen CL, Langballe O, Petersen BL, Cortes D (2011) The challenge of early surgery for cryptorchidism. Scand J Urol Nephrol 45:184–189

    Article  PubMed  CAS  Google Scholar 

  • Vinardi S, Magro P, Manenti M, Lala R, Costantinos S, Cortese MG, Canavese F (2001) Testicular function in men treated in childhood for undescended testes. J Pediatr Surg 36:385–388

    Article  PubMed  CAS  Google Scholar 

  • Wood HM, Elder JS (2009) Cryptorchidism and testicular cancer: separating fact from fiction. J Urol 181:452–461

    Article  PubMed  Google Scholar 

  • Zerella JT, McGill LC (1993) Survival of nonpalpable testicles after orchidopexy. J Pediatr Surg 28:51–253

    Google Scholar 

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© 2012 Springer-Verlag Berlin Heidelberg

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Kaiser, G.L. (2012). Cryptorchidism, Empty Scrotum. In: Symptoms and Signs in Pediatric Surgery. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-31161-1_31

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  • DOI: https://doi.org/10.1007/978-3-642-31161-1_31

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