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Urinary Tract Infection

  • Georges L. Kaiser
Chapter

Abstract

Urinary tract infection belongs to the most common bacterial infections in childhood: 3–5 % of girls and 1–2 % of boys suffer from it until puberty. In infancy, boys are preferably involved and later girls with a reinfection rate of two thirds. Five percent of infants with fever (≥38 °C) have a urinary tract infection.

Numerous urogenital malformations and other disorders manifest uniformly and nearly exclusively by a urinary tract infection if they are not recognized incidentally by prenatal ultrasound or on the occasion of a medical check-up postnatally.

It makes matter worse that the clinical presentation of urinary tract infection is the more unspecific, the younger the child. Burning and pain at micturition (dysuria), pollakiuria, secondary enuresis, and suprapubic, upper abdominal, or flank pain are not recognized as such and reported by the patient until beginning school age.

Keywords

Urinary Tract Infection Autosomal Dominant Polycystic Kidney Disease Complicated Urinary Tract Infection Autosomal Recessive Polycystic Kidney Disease Febrile Urinary Tract Infection 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Bibliography

General: Urinary Tract Infection, Pyelonephritis and Renovascular Hypertension, and Urinary Tract Anomalies

  1. Armengol CE, Hendley JO, Schlager TA (2001) Should we abandon standard microscopy when screening for urinary tract infections in young children? Pediatr Infect Dis 20:1176–1177CrossRefGoogle Scholar
  2. Becker AM (2009) Postnatal evaluation of infants with an abnormal antenatal renal sonogram. Curr Opin Pediatr 21:207–213PubMedCrossRefGoogle Scholar
  3. Benador D, Benador N, Slosman D et al (1997) Are younger children at highest risk of renal sequelae after pyelonephritis? Lancet 349:17–19PubMedCrossRefGoogle Scholar
  4. Burnei G, Burnei A, Hodorogea D, Dräghici I, Georgescu I, Vlad C, Gavriliu S (2009) Diagnosis and complications of renovascular hypertension in children: literature data and clinical observations. J Med Life 2:18–28PubMedGoogle Scholar
  5. Farnham SB, Adams MC, Brock JW 3rd, Pope JC 4th (2005) Pediatric urological causes of hypertension. J Urol 173:697–704PubMedCrossRefGoogle Scholar
  6. Gorelick MH, Shaw KN (2000) Clinical decision rule to identify febrile young girls at risk for urinary tract infection. Arch Pediatr Adolesc Med 154:368–390Google Scholar
  7. Grapin C, Auber F, de Vries P, Audry G, Helardot P (2003) Postnatal management of urinary tract anomalies after antenatal diagnosis. J Gynecol Obstet Biol Reprod (Paris) 32:300–313Google Scholar
  8. Hendren WH et al (1982) Surgically correctable hypertension of renal origin in childhood. Am J Surg 143:432PubMedCrossRefGoogle Scholar
  9. Hoberman A, Chao HP, Keller DM, Hickey R, Davis HW, Elllis D (1993) Prevalence of urinary tract infection in febrile infants. J Pediatr 123:17–23PubMedCrossRefGoogle Scholar
  10. Hoberman A, Charron M, Hickey RW et al (2003) Imaging studies after a first febrile urinary tract infection in young children. N Engl J Med 348:195–202PubMedCrossRefGoogle Scholar
  11. Kaplan RE, Springate JE, Feld EG (1997) Screening dipstick urinalysis: a time to change. Pediatrics 100:919–921PubMedCrossRefGoogle Scholar
  12. Landau D, Turner ME, Brennan J, Majd M (1994) The value of urinalysis in differentiating acute pyelonephritis from lower urinary tract infection in febrile infants. Pediatr Infect Dis J 13:777–781PubMedCrossRefGoogle Scholar
  13. Michael M, Hodson EM, Craig JC et al (2002) Short compared with standard duration of antibiotic treatment for urinary tract infection: a systematic review of randomised controlled trials. Arch Dis Child 87:118–123PubMedCrossRefGoogle Scholar
  14. Mingin GC, Hinds A, Nguyen HT, Baskin LS (2004) Children with a febrile urinary tract infection and a negative radiological work-up: factors predictive of recurrence. Urology 63:562–565, discussion 565PubMedCrossRefGoogle Scholar
  15. Newman TB, Bernzweig JA, Takayama JL et al (2002) Urine testing and urinary tract infections in febrile infants seen in office settings: the pediatric research in office Settings’ febrile infant study. Arch Pediatr Adolesc Med 156:44–54PubMedGoogle Scholar
  16. Sheih CP, Liu MB, Hung CS, Yank KH, Chen WY, Lin CY et al (1989) Renal abnormalities in schoolchildren. Pediatrics 84:1086–1090PubMedGoogle Scholar
  17. Williams G, Lee A, Craig J (2001) Antibiotics for the prevention of urinary tract infection in children: a systematic review of randomized controlled trials. J Pediatr 138:868–874PubMedCrossRefGoogle Scholar

Section 27.1

  1. Bukowski TP, Smith CA (2000) Monfort abdominoplasty with neoumbilical modification. J Urol 164:1711–1713PubMedCrossRefGoogle Scholar
  2. Byun E, Merguerian PA (2006) A meta-analysis of surgical practice patterns in the endoscopic management of ureteroceles. J Urol 176:1871–1877, discussion 1877PubMedCrossRefGoogle Scholar
  3. Dénes FT, Arap MA, Giron AM, Silva FA, Arap S (2004) Comprehensive surgical treatment of prune belly syndrome: 17 years’ experience with 32 patients. Urology 64:789–793, discussion 793–794PubMedCrossRefGoogle Scholar
  4. Franc JD et al (1998a) In: O’Neill JA Jr (ed) Pediatric surgery, vol II, 5th edn. Mosby, St. LouisGoogle Scholar
  5. Hendren WH, Mitchell ME (1979) Surgical correction of ureteroceles. J Urol 121:590–597PubMedGoogle Scholar
  6. Hendren WH, Carr MC, Adams MC (1998) Megaureter and Prune-Belly syndrome. In: O’Neill JA Jr et al (eds) Pediatric surgery, vol II, 5th edn. Mosby, St. LouisGoogle Scholar
  7. Levine E, Taub PJ, Franco I (2007) Laparoscopic-assisted abdominal wall reconstruction in prune-belly syndrome. Ann Plast Surg 58:162–165PubMedCrossRefGoogle Scholar
  8. Patil KK, Duffy PG, Woodhouse CR, Ransley PG (2004) Long-term outcome of Fowler-Stephens orchidopexy in boys with prune-belly syndrome. J Urol 171:1666–1669PubMedCrossRefGoogle Scholar
  9. Pfister RC, Hendren WH (1978) Primary megaureter in children and adults. Clinical and pathophysiological features of 150 ureters. Urology 12:161–176Google Scholar
  10. Prieto J, Ziada A, Baker L, Snodgrass W (2009) Ureteroureterostomy via inguinal incision for ectopic ureters and ureteroceles without ipsilateral lower pole reflux. J Urol 181:1844–1848, discussion 1848–1850PubMedCrossRefGoogle Scholar
  11. Stehr M, Metzger R, Schuster T, Porn U, Dietz HG (2002) Management of the primary obstructed megaureter (PMO) and indication for operative treatment. Eur J Pediatr Surg 12:32–37PubMedCrossRefGoogle Scholar
  12. Woods AG, Brandon DH (2007) Prune belly syndrome. A focused physical assessment. Adv Neonatal Care 7:132–143, quiz 144–145PubMedCrossRefGoogle Scholar
  13. Yoo E, Kim H, Chung S (2007) Bladder surgery as first-line treatment of complete duplex system complicated with ureterocele. J Pediatr Urol 3:291–294PubMedCrossRefGoogle Scholar
  14. Ziylan O, Oktar T, Korgali E, Nane I, Alp T, Ander H (2005) Lower urinary tract reconstruction in ectopic ureteroceles. Urol Int 74:123–126PubMedCrossRefGoogle Scholar

Section 27.2

  1. Afshar K, Papanikolaou F, Malek R, Bagli D, Pipppi-Salle JL, Khoury A (2005a) Vesicoureteral reflux and complete ureteral duplication. Conservative or surgical management? J Urol 173:1725–1727PubMedCrossRefGoogle Scholar
  2. Bettex M, Kummer-Vago M, Kuffer F (1970) Ure­teroneocystostomy in refluxing ureteric duplications: indications, technique and results. J Pediatr Surg 5:622–627PubMedCrossRefGoogle Scholar
  3. Chacko JK, Koyle MA, Mingin GC, Furness PD 3rd (2007) Ipsilateral ureteroureterostomy in the surgical management of the severely dilated ureter in ureteral duplication. J Urol 178:1689–1692PubMedCrossRefGoogle Scholar
  4. Franc JD et al (1998b) Ureteral duplication and ureterocele. In: O’Neill JA Jr (ed) Pediatric surgery, vol II. Mosby, St. LouisGoogle Scholar
  5. Ganz A, Roloff J, Walz PH (1996) Der “ectopic pathway” – Fakt oder Fiktion? Akt Urol 27:419–421CrossRefGoogle Scholar
  6. Grob C, Bettex M (1976) Die ektopische Uretermündung. Bericht über 18 Fälle (The ectopic ureteral orifice). Z Kinderchir 19:279–289Google Scholar
  7. Leissner J, Filipas D, Buff S, Gottscholl M, Fisch M, Beetz R, Schumacher R, Hohenfellner R (1998) Operative Therapiekonzepte bei Doppelnieren. Akt Urol 29:135–138CrossRefGoogle Scholar
  8. Schaerli AF, Bettex M (1973) Die Behandlung der Doppelniere durch die interpyelische Anastomose. Akt Urol 4:245–253Google Scholar
  9. Shah HN, Sodha H, Khandkar AA, Kharodawala S, Hedge SS, Bansal M (2008) Endoscopic management of adult orthotopic ureterocele and associated calculi with holmium laser: experience with 16 patients over 4 years and review of the literature. J Endourol 22:489–496PubMedCrossRefGoogle Scholar
  10. Steffens J, Oberschulte-Beckmann D, Siller V, Röttger P (1998) Ektoper, refluxiver, in eine Samenblasenzyste mündender Ureter mit ipsilateraler zystischer Nierendysplasie. Akt Urol 29:264–266CrossRefGoogle Scholar
  11. Storm DW, Modi A, Jayanthi VR (2010) Laparoscopic ipsilateral ureteroureterostomy in the management of ureteral ectopia in infants and children. J Pediatr Urol 7:529–533PubMedCrossRefGoogle Scholar

Section 27.3

  1. Bouckaert JI, Kuffer F, Bettex M (1970) Die Hufeisenniere. Z Kinderchir 8:268–281Google Scholar
  2. Melchior SW, Fichtner JD, Nierhoff C, Hohenfellner R (1998) Therapie der symptommatischen Hufeisenniere. Akt Urol 29:267–271CrossRefGoogle Scholar
  3. Mouriquand P (1998) Renal fusion and ectopia. In: O’Neill JA Jr et al (eds) Pediatric surgery, vol II, 5th edn. Mosby, St. LouisGoogle Scholar

Section 27.4

  1. Strand WR (2004) Initial management of complex pediatric disorders: prune-belly syndrome, posterior urethral valves. Urol Clin North Am 31:399–415, viiPubMedCrossRefGoogle Scholar

Section 27.5

  1. Kaplan BS (1998) Agenesis, dysplasia, and cystic disease. In: O’Neill JA Jr et al (eds) Pediatric surgery, vol II, 5th edn. Mosby, St. LouisGoogle Scholar

Section 27.6

  1. Abdulhannan P, Stahlschmidt J, Subramaniam R (2011) Multicystic dysplastic kidney disease and hypertension: clinical and pathological correlation. J Pediatr Urol 7:566–568PubMedCrossRefGoogle Scholar
  2. Chiappinelli A, Savanelli A, Farina A, Settimi A (2011) Multicystic dysplastic kidney: our experience in non-surgical management. Pediatr Surg Int 27:775–779PubMedCrossRefGoogle Scholar
  3. de Lichtenberg MH, Nielsen OS (1989) Infected renal cyst simulating acute abdomen. Acta Chir Scand 1055:135Google Scholar
  4. Frishman E, Orron DE, Heiman Z, Kessler A, Kaver I, Graif M (1994) Infected renal cysts: sonographic diagnosis and management. J Ultrasound Med 13:7–10PubMedGoogle Scholar
  5. Guay-Woodford LM, Desmond RA (2003) Autosomal recessive polycystic kidney disease: the clinical experience in North America. Pediatrics 111:1072–1080PubMedCrossRefGoogle Scholar
  6. Hayes WN, Watson AR, Trent and Anglia MCDK Study Group (2012) Unilateral multicystic dysplastic kidney: does initial size matter? Pediatr Nephrol 27:1335–1340PubMedCrossRefGoogle Scholar
  7. Lin CC, Tsai JD, Sheu JC, Lu HJ, Chang BP (2010) Segmental multicystic dysplastic kidney in children: clinical presentation, imaging finding, management, and outcome. J Pediatr Surg 45:1856–1862PubMedCrossRefGoogle Scholar
  8. Padevit C, Jaeger P (2005) Infizierte solitäre Nierenzyste: eine seltene Ursache von Flankenschmerzen. Schweiz Med Forum 5:153–154Google Scholar
  9. Pei Y, Obaji J, Dupuis A, Paterson AD, Magistroni R, Dicks E et al (2009) Unified criteria for ultrasonographic diagnosis of ADPKD. J Am Soc Nephrol 20(1):205–212PubMedCrossRefGoogle Scholar
  10. Shneider BL, Magid MS (2005) Liver disease in autosomal recessive polycystic kidney disease. Pediatr Transplant 9:634–639PubMedCrossRefGoogle Scholar
  11. Torres VE, Harris PC, Pirson Y (2007) Autosomal dominant polycystic kidney disease. Lancet 369(9569):1287–1301PubMedCrossRefGoogle Scholar
  12. Wacksman J, Phipps L (1993) Report of the multicystic kidney registry: preliminary findings. J Urol 150:1870–1872PubMedGoogle Scholar

Section 27.7

  1. Elder JS (1992) Commentary: importance of antenatal diagnosis of vesicoureteral reflux. J Urol 148:1750–1754PubMedGoogle Scholar
  2. Elder JS, Peters CA, Arant BS Jr, Ewalt DH, Hawtrey CE, Hurwitz RS et al (1997) Pediatric reflux guidelines panel summary report on the management of primary vesicoureteral reflux in children. J Urol 157:1846–1851PubMedCrossRefGoogle Scholar
  3. Jacobson SH, Hansson S, Jakobsson B (1999) Vesico-ureteric reflux: occurrence and long-term risks. Acta Paeditr Suppl 88:22–30CrossRefGoogle Scholar
  4. Jodal U, Koskimies O, Hanson E, Lohr G, Olbing H, Smellie J et al (1992) Infection patterns in children with vesicoureteral reflux randomly allocated to operation or long-term antibacterial prophylaxis. The International Reflux Study in Children. J Urol 148:1650–1652PubMedGoogle Scholar
  5. Kirsch AJ, Hensle T, Scherz HC, Koyle M (2006) Injection therapy: advancing the treatment of vesicoureteral reflux. J Pediatr Urol 2:539–544PubMedCrossRefGoogle Scholar
  6. Läckgren G (2003) Endoscopic treatment of vesicoureteral reflux and urinary incontinence in children. AUA update series, vol XXII, Lesson 37:294–299Google Scholar
  7. Olbing H, Claesson I, Ebel KD, Seppänen U, Smellie JM, Tamminen-Möbius T, and Wikstad on behalf of the International Reflux Study in Children (1992) Renal scars and parenchymal thinning in children with vesicoureteral reflux: a 5-year report of the International Reflux Study in children (European Branch). J Urol 148:1653–1656PubMedGoogle Scholar
  8. Olbing H, Hirche K, Koskimies O et al (2000) Renal growth in children with severe vesicoureteral reflux: 10-year prospective study of medical versus surgical treatment: the International Reflux Study in Children (European branch). Radiology 216:731–737PubMedGoogle Scholar
  9. Rizzoni G, Dello Strologo L (1989) Aetiologie terminaler Niereninsuffizienz bei Kindern: ein epidemiologischer Ueberblick. Ann Nestlé 47:139–146Google Scholar
  10. Roussey-Kesler G, Gadjos V, Idres N, Horen B, Leclair LI, Raymond F, Grellier A, Hazart I, de Parscau L, Salomon R, Champion G, Leroy V, Guigonis V, Siret D, Palcoux JB, Taque S, Lemoigne A, Nguyen JM, Guyot C (2008) Antibiotic prophylaxis of recurrent urinary tract infection in children with Low grade vesicoureteral reflux: results from a prospective randomized study. J Urol 179:674–679PubMedCrossRefGoogle Scholar
  11. Smelli JM, Tamminen-Möbius T, Olbing H, Claesson I, Wikstad I, Jodal U, Seppänen U (1992) Five-year study of medical or surgical treatment in children with severe reflux: radiological renal findings. The International Reflux Study in Children. Pediatr Nephrol 6:223–230CrossRefGoogle Scholar
  12. Smellie JM, Jodal U, Lax H et al (2001a) Outcome at 10 years of severe vesicoureteral reflux managed medically: report of the International Reflux Study in Children. J Pediatr 139:656–663PubMedCrossRefGoogle Scholar
  13. Smellie JM, Barrat TM, Chantler C et al (2001b) Medical versus surgical treatment in children with severe bilateral vesicoureteral reflux and bilateral nephropathy: a randomised trial. Lancet 357:1329–1333PubMedCrossRefGoogle Scholar
  14. Stenberg A, Läckgren G (2007) Treatment of vesicoureteral reflux in children using stabilized non-animal hyaluronic acid/dextranomer gel (NASHA/DX): a long-term observational study. J Pediatr Urol 3:80–85PubMedCrossRefGoogle Scholar
  15. Tamminen-Möbius T, Brunier E, Ebel KD, Lebowitz R, Olbing H, Seppänen U, Sixt R, on behalf of the International Reflux Study in Children (1992) Cessation of vesicoureteral reflux for 5 years in infants and children allocated to medical treatment. J Urol 148:1662–1666PubMedGoogle Scholar
  16. Tibballs JM, De Bruyn R (1996) Primary vesicoureteral reflux – how useful is postnatal diagnosis. Arch Dis Child 75:444–447PubMedCrossRefGoogle Scholar
  17. Weiss R, Duckett J, Spitzer A (1992) Results of a randomized clinical trial of medical versus surgical management of infants and children with grades II and IV primary vesicoureteral reflux (United States). The International Reflux Study in Children. J Urol 148:1667–1673PubMedGoogle Scholar
  18. Wheeler D, Vimalachandra D, Hodson EM, Roy LP, Smith G, Craig JC (2003) Antibiotics and surgery for vesicoureteral reflux: a meta-analysis of randomised controlled trials. Arch Dis Child 88:688–694PubMedCrossRefGoogle Scholar

Section 27.8

  1. Afshar K, Malek R, Bakhshi M, Papanikolaou F, Farhat W, Bagli D, Khoury AE, Pippi-Salle JL (2005b) Should the presence of congenital para-ureteral diverticulum affect the management of vesico-ureteral reflux? J Urol 174:1590–1593PubMedCrossRefGoogle Scholar

Section 27.9

  1. Raez M (1977) Zur Aetiologie der Cystitis granularis. Nachweis eines Harnröhren-Blasen-Refluxes von Badewasser beim Baden und Waschen von kleinen Mädchen. Akt Urol 8:151–158Google Scholar

Section 27.10

  1. Akporiaye LE, Jordan GH, Devine C Jr, American Urological Association, Inc (eds) (1997) Balanitis xerotica obliterans (BXO), vol XVI, AUA update series. Office of Education, Houston, Lesson 21Google Scholar
  2. Craig JC, Knight JF, Sureshkumar P et al (1996) Effect of circumcision on the incidence of urinary tract infection in preschool boys. J Pediatr 128:23–27PubMedCrossRefGoogle Scholar
  3. Das S, Tunuguntla HS (2000) Balanitis xerotica obliterans – a review. World J Urol 18:382–387PubMedCrossRefGoogle Scholar
  4. Ellis DG, Mann CM Jr (1998) Abnormalities of the urethra, penis, and scrotum. In: O’Neill JA Jr et al (eds) Pediatric surgery, vol II, 5th edn. Mosby, St. LouisGoogle Scholar
  5. Horowitz M, Gershbein AB (2001) Gomco circumcision: when is it safe? J Pediatr Surg 36:1047–1049PubMedCrossRefGoogle Scholar
  6. Morris BJ (2007) Why circumcision is a biomedical imperative for the 21th century. Bioessays 29:1147–1158PubMedCrossRefGoogle Scholar
  7. Pugliese JM, Morey AF, Peterson AC (2007) Lichen sclerosus: review of the literature and current recommendations for management. J Urol 178:2268–2276. Comment in: J Urol (2009) 181:1502–1503PubMedCrossRefGoogle Scholar
  8. Wiswell TE, Geschke DW (1989) Risks from circumcision during the first month of life compared with those for uncircumcised boys. Pediatrics 83:1011–1015PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Georges L. Kaiser
    • 1
  1. 1.Department of Pediatric Surgery InselspitalUniversity of BerneBerneSwitzerland

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