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Jaundice (Icterus)

  • Georges L. Kaiser
Chapter

Abstract

Jaundice is a frequent sign in newborns and young infants and much less frequently later in life. The causal hyperbilirubinemia (>100 μmol/l total bilirubin needed) is a result of decreased hepatic uptake, conjugation of bilirubin, biliary excretion, or increased degradation of hemoglobin.

Hyperbilirubinemia is divided for practical purposes into two forms: indirect hyperbilirubinemia in which the unconjugated bilirubin is increased and direct hyperbilirubinemia with increased direct or conjugated bilirubin (direct bilirubin >15 % of total bilirubin/total bilirubin >35 μmol/l).

Keywords

Sickle Cell Anemia Biliary Atresia Turner Syndrome Choledochal Cyst Pyloric Stenosis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Bibliography

General and Differential Diagnosis Jaundice

  1. Ling SC (2007) Congenital cholestatic syndromes: what happens when children grow up? Can J Gastroenterol 21:743–751PubMedGoogle Scholar
  2. Mazigh MS, Aloui N, Fetni I, Boukthir S, Aissa K, Sellami N, Bellagha I, Bousnina S, Barsaoui S (2006) Congenital hepatic fibrosis in children. Report of 9 cases and review of the literature. Tunis Med 84:182–188PubMedGoogle Scholar
  3. Medeiros FS, Tavares-Neto J, D’Oliveira A Jr, Parana R (2007) Liver injury in visceral leishmaniasis in children: systematic review. Acta Gastroenterol Latinoam 37:150–157PubMedGoogle Scholar
  4. Pariente D, Franchi-Abella S (2010) Paediatric chronic liver disease: how to investigate and follow up? Pediatr Radiol 40:906–919PubMedCrossRefGoogle Scholar
  5. Shneider BL, Magid MS (2005) Liver disease in autosomal recessive polycystic kidney disease. Pediatr Transplant 9:634–639PubMedCrossRefGoogle Scholar

Section 25.1

  1. Duché M, Ducot B, Tournay E, Fabre M, Cohen J, Jacquemin E, Bernard O (2010) Prognostic value of endoscopy in children with biliary atresia at risk for early development of varices and bleeding. Gastroenterology 139:1952–1960PubMedCrossRefGoogle Scholar
  2. Erlichman J, Hohlweg K, Haber BA (2009) Biliary atresia: how medical complications and therapies impact outcome. Expert Rev Gastroenterol Hepatol 3:425–434PubMedCrossRefGoogle Scholar
  3. Hsiao CH, Chang MH, Chen HL, Lee HC, Wu TC, Lin CC et al (2008) Universal screening for biliary atresia using an infant stool color card in Taiwan. Hepatology 47:1233–1240PubMedCrossRefGoogle Scholar
  4. Kelly DA, Davenport M (2007) Current management of biliary atresia. Arch Dis Child 92:1132–1135PubMedCrossRefGoogle Scholar
  5. Lai MW, Chang MH, Hsu SC, Hsu HC, Su CT, Kao CL, Lee CY (1994) Differential diagnosis of extrahepatic biliary atresia from neonatal hepatitis: a prospective study. J Pediatr Gastroenterol Nutr 18:121–127PubMedCrossRefGoogle Scholar
  6. Le Coultre C, Battaglin C, Bugmann P, Genin B, Bachmann R, McLin V, Mentha G, Belli D (2001) Biliary atresia and orthotopic liver transplantation. 11 years of experience in Geneva. Swiss Surg 7:199–204PubMedCrossRefGoogle Scholar
  7. Ohi R, Nio M (1998) The jaundiced infant: biliary atresia and other obstructions. In: O’Neill JA Jr et al (eds) Pediatric surgery, vol II, 5th edn. Mosby, St. LouisGoogle Scholar
  8. Sinha CK, Davenport M (2008) Biliary atresia. J Indian Assoc Pediatr Surg 13:49–56PubMedCrossRefGoogle Scholar
  9. Wildhaber BE, Majno P, Mayr J, Zachariou Z, Hohlfeld J, Schwoebel M et al (2008) Biliary atresia: Swiss national study, 1994–2004. J Pediatr Gastroenterol Nutr 46:299–307PubMedCrossRefGoogle Scholar
  10. Wildhaber BE, McLin VA (2010) Schweizerisches Screeningprogramm für Gallen-atresie. Schweiz Med Forum 10:480–482Google Scholar

Section 25.2

  1. Altman RP, Hicks BA (1995) Choledochal cyst. In: Spitz L, Coran AG (eds) Rob & Smith operative surgery. Chapman & Hall, LondonGoogle Scholar
  2. Arda IS, Tuzun M, Aliefendioglu D, Hicsonmez A (2005) Spontaneous rupture of extrahepatic choledochal cyst: two pediatric cases and literature review. Eur J Pediatr Surg 15:361–363PubMedCrossRefGoogle Scholar
  3. Blockhorn M, Malago M, Lang H, Nadalin S, Paul A, Saner F et al (2006) The role of surgery in Caroli’s disease. J Am Coll Surg 202:928–932CrossRefGoogle Scholar
  4. Caroli J, Soupault R, Kossakowski J, Plocker L, Para­dowska M (1958) La dilatation polycystic congénitale des voies biliaires intrahéepatique. Sem Hop 34:488–495PubMedGoogle Scholar
  5. Lipsett PA, Pitt HA (2003) Surgical treatment of choledochal cysts. J Hepatobiliary Pancreat Surg 10:352–359PubMedCrossRefGoogle Scholar
  6. Miller WJ, Sechtin AG, Campbell WL, Pieters PC (1995) Imaging findings in Caroli’s disease. Am J Roentgenol 165:333–337Google Scholar
  7. O’Neill JA Jr (1998) Choledochal cyst. In: O’Neill JA Jr et al (eds) Pediatric surgery, vol II, 5th edn. Mosby, St. LouisGoogle Scholar
  8. Stalder PA, Desbiolles AM, Neff U (1996) Choledochuskarzinom in Choledochuszy-ste – eine Rarität. Präsentation des Krankheitsbildes anhand eines Fallbeispieles. (Carcinoma within a choledochal cyst. A case report). Swiss Surg 5:123–126Google Scholar
  9. Takahashi T, Shimotakahara A, Okazaki T, Koga H, Miyano G, Lane GJ, Yamataka A (2010) Intraoperative endoscopy during choledochal cyst excision: extended long-term follow-up compared with recent cases. J Pediatr Surg 45:379–382PubMedCrossRefGoogle Scholar
  10. Todani T, Watanabe W, Toki A et al (1987) Carcinoma related to choledochal cyst with internal drainage operations. Surg Gynecol Obstet 164:61–64PubMedGoogle Scholar

Section 25.3

  1. Wang JS, Wang XH, Zhu QR, Wang ZL, Hu XQ, Zheng S (2008) Clinical and pathological characteristics of Alagille syndrome in Chinese children. World J Pediatr 4:283–288PubMedCrossRefGoogle Scholar

Section 25.4

  1. Davenport M, Betalli P, D’Antiga L, Cheeseman P, Mieli-Vergani G, Howard ER (2003) The spectrum of surgical jaundice. J Pediatr Surg 38:1471–1479PubMedCrossRefGoogle Scholar
  2. Yeh ML, Chang PC (2012) Laparoscopic cholecystostomy and bile duct lavage for treatment of inspissated bile syndrome: a single-centre experience. World J Pediatr 8:88, author replay 88PubMedCrossRefGoogle Scholar

Section 25.5

  1. Holcomb GE III, Pietsch JB (1998) Gallbladder disease and hepatic infections. In: O’Neill JA Jr et al (eds) Pediatric surgery, vol II, 5th edn. Mosby, St. LouisGoogle Scholar

Section 25.6

  1. Ozdemir T, Akgül AK, Arpaz Y, Arikan A (2008) Spon­taneous bile duct perforation: a rare cause of acute abdominal pain during childhood. Ulus Travma Acil Cerrahi Derg 14:211–215PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Georges L. Kaiser
    • 1
  1. 1.Department of Pediatric Surgery InselspitalUniversity of BerneBerneSwitzerland

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