Germ Cell TumorsOpen image in new window

  • Jean Noel Buy
  • Michel Ghossain


In adults, 30 % of ovarian tumors are of germ cell origin [1]; the great majority of germ cell tumors (95 %) are benign and consist of mature cystic teratomas (MCT), usually designated dermoid cysts [2]. In children and adolescents, more than 60 % of ovarian neoplasms are of germ cell origin, and one-third of them are malignant [2–6].


Germ Cell Tumor Mucinous Tumor Dermoid Cyst Mature Teratoma Cystic Content 
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  1. 1.
    Katsube Y, Berg JW, Silverberg SG (1982) Epidemiologic pathology of ovarian tumors: a histopathologic review of primary ovarian neoplasms diagnosed in the Denver Standard Metropolitan Statistical Area, 1 July-31 December 1969 and 1 July-31 December 1979. Int J Gynecol Pathol 1:3–16PubMedCrossRefGoogle Scholar
  2. 2.
    Talerman A (1987) Germ cell tumors of the ovary. In: Kurman RJ (ed) Blaustein’s pathology of the female genital tract, 3rd edn. Springer, New-York, pp 659–721CrossRefGoogle Scholar
  3. 3.
    Abell MR, Johnson VJ, Holtz F (1965) Ovarian neoplasms in childhood and adolescence. Part 1. Tumors of germ cell origin. Am J Obstet Gynecol 92:1059PubMedGoogle Scholar
  4. 4.
    Breen JL, Neubecker RD (1967) Ovarian malignancy in children, with special reference to the germ-cell tumors. Ann N Y Acad Sci 142:658–674PubMedCrossRefGoogle Scholar
  5. 5.
    Breen JL, Maxson WS (1977) Ovarian tumors in children and adolescents. Clin Obstet Gynecol 20:607–623PubMedCrossRefGoogle Scholar
  6. 6.
    Norris HJ, Jensen RD (1972) Relative frequency of ovarian neoplasms in children and adolescents. Cancer 30:713–719PubMedCrossRefGoogle Scholar
  7. 7.
    Scully RE, Young RH, Clement PB (1998) Tumors of the ovary, maldeveloped gonads, fallopian tubes and broad ligament, 3rd edn. Armed Force Institute of Pathology, Washington, DC, pp 239–312Google Scholar
  8. 8.
    Caruso PA, Marsh MR, Minkowitz S, Karten G (1971) An intense clinicopathologic study of 305 teratomas of the ovary. Cancer 27:343–348PubMedCrossRefGoogle Scholar
  9. 9.
    Peterson WF, Prevost EC, Edmunds FT, Hundley JM Jr, Morris FK (1955) Benign cystic teratomas of the ovary. A clinico-statistical study of 1007 cases with review of the literature. Am J Obstet Gynecol 70:368–382PubMedGoogle Scholar
  10. 10.
    Malkasian GD Jr, Dockerty MB, Symmonds RE (1967) Benign cystic teratomas. Obstet Gynecol 29:719–725PubMedGoogle Scholar
  11. 11.
    Buy JN, Ghossain MA, Moss AA et al (1989) Cystic teratoma of the ovary: CT detection. Radiology 171:697–701PubMedGoogle Scholar
  12. 12.
    Jones HW Jr, Jones GS (1979) Germ cell tumors of the ovary. In: Jones HW Jr, Jones GS (eds) Novak’s textbook of gynecology, 10th edn. Saunders, Philadelphia, pp 559–580Google Scholar


  1. 13.
    Blackwell WJ, Dockerty MB, Masson JC, Mussey RD (1946) Dermoid cysts of the ovary: clinical and pathological significance. Am J Obstet ­Gynecol 51:151PubMedGoogle Scholar
  2. 14.
    Laing FC, Van Dalsem V, Marks WM, Barton JL, Martinez DA (1981) Dermoid cysts of the ovary: their ultrasonographic appearances. Obstet Gynecol 57:99–104, JID – 0401101PubMedGoogle Scholar
  3. 15.
    Hertzberg BS, Kliewer MA (1996) Sonography of benign cystic teratoma of the ovary: pitfalls in diagnosis. AJR Am J Roentgenol 167:1127–1133PubMedCrossRefGoogle Scholar
  4. 16.
    Mais V, Guerriero S, Ajossa S, Angiolucci M, Paoletti AM, Melis GB (1995) Transvaginal ultrasonography in the diagnosis of cystic teratoma. Obstet Gynecol 85:48–52PubMedCrossRefGoogle Scholar
  5. 17.
    Sandler MA, Silver TM, Karo JJ (1979) Gray-scale ultrasonic features of ovarian teratomas. Radiology 131:705–709PubMedGoogle Scholar
  6. 18.
    Patel MD, Feldstein VA, Lipson SD, Chen DC, Filly RA (1998) Cystic teratomas of the ovary: diagnostic value of sonography. AJR Am J Roentgenol 171:1061–1065PubMedCrossRefGoogle Scholar
  7. 19.
    Bronshtein M, Yoffe N, Brandes JM, Blumenfeld Z (1991) Hair as a sonographic marker of ovarian teratomas: improved identification using transvaginal sonography and simulation model. J Clin Ultrasound 19:351–355PubMedCrossRefGoogle Scholar
  8. 20.
    Malde HM, Kedar RP, Chadha D, Nayak S (1992) Dermoid mesh: a sonographic sign of ovarian teratoma. AJR Am J Roentgenol 159:1349–1350PubMedCrossRefGoogle Scholar
  9. 21.
    Sheth S, Fishman EK, Buck JL, Hamper UM, Sanders RC (1988) The variable sonographic appearances of ovarian teratomas: correlation with CT. AJR Am J Roentgenol 151:331–334PubMedCrossRefGoogle Scholar
  10. 22.
    Serafini G, Quadri PG, Gandolfo NG, Gandolfo N, Martinoli C, Derchi LE (1999) Sonographic features of incidentally detected, small, nonpalpable ovarian dermoids. J Clin Ultrasound 27:369–373PubMedCrossRefGoogle Scholar
  11. 23.
    Owre A, Pedersen JF (1991) Characteristic fat-fluid level at ultrasonography of ovarian dermoid cyst. Acta Radiol 32:317–319PubMedCrossRefGoogle Scholar
  12. 24.
    Kawamoto S, Sato K, Matsumoto H et al (2001) Multiple mobile spherules in mature cystic teratomas of the ovary. AJR Am J Roentgenol 176:­1455–1457PubMedCrossRefGoogle Scholar
  13. 25.
    Quinn SF, Erickson S, Black WC (1985) Cystic ovarian teratomas: the sonographic appearance of the dermoid plug. Radiology 155:477–478PubMedGoogle Scholar
  14. 26.
    Laing FC (1994) US analysis of adnexal masses: the art of making the correct diagnosis. Radiology 191:21–22, JID – 0401260PubMedGoogle Scholar
  15. 27.
    Nicolet V, Ethier S, Lamarre L (1984) Sonographic appearances of the wall of ovarian dermoid cysts. J Can Assoc Radiol 35:375–377PubMedGoogle Scholar
  16. 28.
    Maneschi F, Marasa L, Incandela S, Mazzarese M, Zupi E (1993) Ovarian cortex surrounding benign neoplasms: a histologic study. Am J Obstet Gynecol 169:388–393, JID – 0370476PubMedCrossRefGoogle Scholar
  17. 29.
    Sassone AM, Timor-Tritsch IE, Artner A, Westhoff C, Warren WB (1991) Transvaginal sonographic characterization of ovarian disease: evaluation of a new scoring system to predict ovarian malignancy. Obstet Gynecol 78:70–76, JID – 0401101PubMedGoogle Scholar
  18. 30.
    Buy JN, Ghossain MA, Hugol D et al (1996) Characterization of adnexal masses: combination of color Doppler and conventional sonography compared with spectral Doppler analysis alone and conventional sonography alone. AJR Am J Roentgenol 166:385–393, JID – 7708173PubMedCrossRefGoogle Scholar
  19. 31.
    Zalel Y, Caspi B, Tepper R (1997) Doppler flow characteristics of dermoid cysts: unique appearance of struma ovarii. J Ultrasound Med 16:355–358PubMedGoogle Scholar
  20. 32.
    Comerci JT Jr, Licciardi F, Bergh PA, Gregori C, Breen JL (1994) Mature cystic teratoma: a clinicopathologic evaluation of 517 cases and review of the literature. Obstet Gynecol 84:22–28PubMedGoogle Scholar
  21. 33.
    Bloomfield TH (1987) Benign cystic teratomas of the ovary: a review of seventy-two cases. Eur J Obstet Gynecol Reprod Biol 25:231–237PubMedCrossRefGoogle Scholar
  22. 34.
    Caspi B, Appelman Z, Rabinerson D, Zalel Y, Tulandi T, Shoham Z (1997) The growth pattern of ovarian dermoid cysts: a prospective study in premenopausal and postmenopausal women. Fertil Steril 68:501–505PubMedCrossRefGoogle Scholar
  23. 35.
    Caspi B, Levi R, Appelman Z, Rabinerson D, Goldman G, Hagay Z (2000) Conservative management of ovarian cystic teratoma during pregnancy and labor. Am J Obstet Gynecol 182:503–505PubMedCrossRefGoogle Scholar
  24. 36.
    Sisler CL, Siegel MJ (1990) Ovarian teratomas: a comparison of the ­sonographic appearance in prepubertal and postpubertal girls. AJR Am J Roentgenol 154:139–141PubMedCrossRefGoogle Scholar
  25. 37.
    Surratt JT, Siegel MJ (1991) Imaging of pediatric ovarian masses. Radiographics 11:533–548PubMedGoogle Scholar
  26. 38.
    Kim R, Bohm-Velez M (1994) Familial ovarian dermoids. J Ultrasound Med 13:225–228, JID – 8211547PubMedGoogle Scholar


  1. 39.
    Guinet C, Ghossain MA, Buy JN et al (1995) Mature cystic teratomas of the ovary: CT and MR findings. Eur J Radiol 20:137–143PubMedCrossRefGoogle Scholar
  2. 40.
    Cawley KM, Mahoney PD, Wilmot MD, Longacre TL (1983) Ovarian dermoid: unusual CT presentation. J Comput Assist Tomogr 7:1116–1117, JID – 7703942PubMedCrossRefGoogle Scholar
  3. 41.
    Muramatsu Y, Moriyama N, Takayasu K, Nawano S, Yamada T (1991) CT and MR imaging of cystic ovarian teratoma with intracystic fat balls. J Comput Assist Tomogr 15:528–529PubMedGoogle Scholar
  4. 42.
    Dodd GD, Lancaster KT, Moulton JS (1989) Ovarian lipoleiomyoma: a fat-containing mass in the female pelvis. AJR Am J Roentgenol 153:1007–1008PubMedCrossRefGoogle Scholar
  5. 43.
    Dodd GD, Budzik RFJ (1990) Lipomatous tumors of the pelvis in women: spectrum of imaging findings. AJR Am J Roentgenol 155:317–322PubMedCrossRefGoogle Scholar
  6. 44.
    Cederlund CG, Karlsson S, Nyman U (1981) Computer tomography of ovarian dermoid cysts. Acta Radiol Diagn (Stockh) 22:435–439Google Scholar
  7. 45.
    Feldberg MA, van Waes PF, Hendriks MJ (1984) Direct multiplanar CT findings in cystic teratoma of the ovary. J Comput Assist Tomogr 8:1131–1135PubMedCrossRefGoogle Scholar
  8. 46.
    Friedman AC, Pyatt RS, Hartman DS, Downey EFJ, Olson WB (1982) CT of benign cystic teratomas. AJR Am J Roentgenol 138:659–665PubMedCrossRefGoogle Scholar
  9. 47.
    Ghossain MA, Buy JN, Bazot M et al (1994) CT in adnexal torsion with emphasis on tubal findings: correlation with US. J Comput Assist Tomogr 18:619–625PubMedCrossRefGoogle Scholar


  1. 48.
    Togashi K, Nishimura K, Itoh K et al (1987) Ovarian cystic teratomas: MR imaging. Radiology 162:669–673PubMedGoogle Scholar
  2. 49.
    Nakayama T, Yoshimitsu K, Irie H et al (2005) Diffusion-weighted echo-planar MR imaging and ADC mapping in the differential diagnosis of ovarian cystic masses: usefulness of detecting keratinoid substances in mature cystic teratomas. Imaging 22:271–278Google Scholar
  3. 50.
    Stevens SK, Hricak H, Campos Z (1993) Teratomas versus cystic hemorrhagic adnexal lesions: differentiation with proton-selective fat-saturation MR imaging. Radiology 186:481–488PubMedGoogle Scholar
  4. 51.
    Bazot M, Boudghene F, Billieres P, Antoine J, Uzan S, Bigot J (2000) Value of fat-suppression gradient-echo MR imaging in the diagnosis of ovarian cystic teratomas. Clin Imaging 24:146–153PubMedCrossRefGoogle Scholar
  5. 52.
    Yamashita Y, Torashima M, Hatanaka Y et al (1994) Value of phase-shift gradient-echo MR imaging in the differentiation of pelvic lesions with high signal intensity at T1-weighted imaging. Radiology 191:759–764PubMedGoogle Scholar
  6. 53.
    Kier R, Smith RC, McCarthy SM (1992) Value of lipid- and water-suppression MR images in distinguishing between blood and lipid within ovarian masses. AJR Am J Roentgenol 158:321–325PubMedCrossRefGoogle Scholar
  7. 54.
    Yamashita Y, Hatanaka Y, Torashima M, Takahashi M, Miyazaki K, ­Okamura H (1994) Mature cystic teratomas of the ovary without fat in the cystic cavity: MR features in 12 cases. AJR Am J Roentgenol 163:­613–616PubMedCrossRefGoogle Scholar
  8. 55.
    Rha SE, Byun JY, Jung SE et al (2004) Atypical CT and MRI manifestations of mature ovarian cystic teratomas. AJR Am J Roentgenol 183:743–750PubMedCrossRefGoogle Scholar
  9. 56.
    Mitchell DG, Vinitski S, Rifkin MD, Burk DLJ (1989) Sampling bandwidth and fat suppression: effects on long TR/TE MR imaging of the abdomen and pelvis at 1.5 T. AJR Am J Roentgenol 153:419–425, JID – 7708173PubMedCrossRefGoogle Scholar
  10. 57.
    Yanai-Inbar I, Scully RE (1987) Relation of ovarian dermoid cysts and immature teratomas: an analysis of 350 cases of immature teratoma and 10 cases of dermoid cyst with microscopic foci of immature tissue. Int J Gynecol Pathol 6:203–212PubMedCrossRefGoogle Scholar
  11. 58.
    Bazot M, Cortez A, Sananes S, Boudghene F, Uzan S, Bigot JM (1999) Imaging of dermoid cysts with foci of immature tissue. J Comput Assist Tomogr 23:703–706PubMedCrossRefGoogle Scholar
  12. 59.
    Allen C, Stephens M, Williams J (1992) Combined high grade sarcoma and serous ovarian neoplasm. J Clin Pathol 45:263–264PubMedCrossRefGoogle Scholar

Collision Tumors

  1. 60.
    Ng WK, Lam KY, Chan AC, Kwong YL (1996) Collision tumour of the oesophagus: a challenge for histological diagnosis. J Clin Pathol 49:524–526PubMedCrossRefGoogle Scholar
  2. 61.
    Schwartz LH, Macari M, Huvos AG, Panicek DM (1996) Collision tumors of the adrenal gland: demonstration and characterization at MR imaging. Radiology 201:757–760PubMedGoogle Scholar
  3. 62.
    Bundy AL, Ritchie WG, Fine C, Brinsko RE (1986) Dermoid tumor and cystadenoma arising in the same ovary. J Clin Ultrasound 14:727–731PubMedCrossRefGoogle Scholar
  4. 63.
    Kim SH, Kim YJ, Park BK, Cho JY, Kim BH, Byun JY (1999) Collision tumors of the ovary associated with teratoma: clues to the correct preoperative diagnosis. J Comput Assist Tomogr 23:929–933PubMedCrossRefGoogle Scholar


  1. 64.
    Hibbard LT (1985) Adnexal torsion. Am J Obstet Gynecol 152:456–461PubMedGoogle Scholar
  2. 65.
    Pantoja E, Noy MA, Axtmayer RW, Colon FE, Pelegrina I (1975) Ovarian dermoids and their complications. Comprehensive historical review. Obstet Gynecol Surv 30:1–20PubMedCrossRefGoogle Scholar
  3. 66.
    Ghossain MA, Buy JN, Sciot C, Jacob D, Hugol D, Vadrot D (1997) CT findings before and after adnexal torsion: rotation of a focal solid element of a cystic adjunctive sign in diagnosis. AJR Am J Roentgenol 169:1343–1346PubMedCrossRefGoogle Scholar
  4. 67.
    Kimura I, Togashi K, Kawakami S, Takakura K, Mori T, Konishi J (1994) Ovarian torsion: CT and MR imaging appearances. Radiology 190:337–341PubMedGoogle Scholar

Malignant Transformation

  1. 68.
    Chadha S, Schaberg A (1988) Malignant transformation in benign cystic teratomas: dermoids of the ovary. Eur J Obstet Gynecol Reprod Biol 29:329–338, JID – 0375672PubMedCrossRefGoogle Scholar
  2. 69.
    Stamp GW, McConnell EM (1983) Malignancy arising in cystic ovarian teratomas. A report of 24 cases. Br J Obstet Gynaecol 90:671–675, JID – 7503752PubMedCrossRefGoogle Scholar
  3. 70.
    Geist SH (1942) Ovarian tumors. Paul B. Hoeber Inc., New York, pp 307–339Google Scholar
  4. 71.
    Lynch EW (1926) Pelvic neoplasms. Appleton & Co, New York, p 358Google Scholar
  5. 72.
    Krumerman MS, Chung A (1977) Squamous carcinoma arising in benign cystic teratoma of the ovary: a report of four cases and review of the literature. Cancer 39:1237–1242PubMedCrossRefGoogle Scholar
  6. 73.
    Climie AR, Heath LP (1968) Malignant degeneration of benign cystic teratomas of the ovary. Review of the literature and report of a chondrosarcoma and carcinoid tumor. Cancer 22:824–832, JID – 0374236PubMedCrossRefGoogle Scholar
  7. 74.
    Skaane P, Klott KJ (1981) Fat – fluid level in a cystic ovarian teratoma. J Comput Assist Tomogr 5:577–579PubMedCrossRefGoogle Scholar
  8. 75.
    Hirakawa T, Tsuneyoshi M, Enjoji M (1989) Squamous cell carcinoma arising in mature cystic teratoma of the ovary. Clinicopathologic and topographic analysis. Am J Surg Pathol 13:397–405PubMedCrossRefGoogle Scholar
  9. 76.
    Miyazaki K, Tokunaga T, Katabuchi H, Ohba T, Tashiro H, Okamura H (1991) Clinical usefulness of serum squamous cell carcinoma antigen for early detection of squamous cell carcinoma arising in mature cystic teratoma of the ovary. Obstet Gynecol 78:562–566PubMedGoogle Scholar
  10. 77.
    Kawai M, Kano T, Kikkawa F et al (1992) Seven tumor markers in benign and malignant germ cell tumors of the ovary. Gynecol Oncol 45:248–253PubMedCrossRefGoogle Scholar
  11. 78.
    Mlikotic A, McPhaul L, Hansen GC, Sinow RM (2001) Significance of the solid component in predicting malignancy in ovarian cystic teratomas; diagnostic considerations. J Ultrasound Med 20:859–866PubMedGoogle Scholar
  12. 79.
    Maslin P, Luchs JS, Hass J, Katz DS (2002) Ovarian teratoma with malignant transformation: CT diagnosis. AJR Am J Roentgenol 178:1574PubMedCrossRefGoogle Scholar
  13. 80.
    Park SB, Kim JK, Kim KR, Cho KS (2007) Preoperative diagnosis of mature cystic teratoma with malignant transformation: analysis of ­imaging findings and clinical and laboratory data. Arch Gynecol ­Obstet 275:25–31PubMedCrossRefGoogle Scholar
  14. 81.
    Kim KA, Park CM, Lee JH et al (2004) Benign ovarian tumors with solid and cystic components that mimic malignancy. AJR Am J Roentgenol 182:1259–1265PubMedCrossRefGoogle Scholar
  15. 82.
    Kido A, Togashi K, Konishi I et al (1999) Dermoid cysts of the ovary with malignant transformation: MR appearance. AJR Am J Roentgenol 172:445–449PubMedCrossRefGoogle Scholar

Dermoid Tumor Omentum

  1. 83.
    Ushakov FB, Meirow D, Prus D, Libson E, BenShushan A, Rojansky N (1998) Parasitic ovarian dermoid tumor of the omentum-A review of the literature and report of two new cases. Eur J Obstet Gynecol Reprod Biol 81:77–82PubMedCrossRefGoogle Scholar
  2. 84.
    Ralls PW, Hartman B, White W, Radin DR, Halls J (1987) Computed tomography of benign cystic teratoma of the omentum. J Comput Assist Tomogr 11:548–549PubMedCrossRefGoogle Scholar
  3. 85.
    Ordonez NG, Manning JTJ, Ayala AG (1983) Teratoma of the omentum. Cancer 51:955–958, JID – 0374236PubMedCrossRefGoogle Scholar
  4. 86.
    Spurney RF, McCormack KM (1987) Immature omental teratoma. Arch Pathol Lab Med 111:762–764, JID – 7607091PubMedGoogle Scholar

Immature Teratoma

  1. 87.
    Breen JL, Neubecker RD (1963) Malignant teratoma of the ovary. An analysis of 17 cases. Obstet Gynecol 21:669PubMedGoogle Scholar
  2. 88.
    Malkasian GD Jr, Symmonds RE, Dockerty MB (1965) Malignant ovarian teratomas. Report of 31 cases. Obstet Gynecol 25:810PubMedGoogle Scholar
  3. 89.
    Robboy SJ, Scully RE (1970) Ovarian teratoma with glial implants on the peritoneum. An analysis of 12 cases. Hum Pathol 1:643–653PubMedCrossRefGoogle Scholar
  4. 90.
    Norris HJ, Zirkin HJ, Benson WL (1976) Immature (malignant) teratoma of the ovary: a clinical and pathologic study of 58 cases. Cancer 37:2359–2372PubMedCrossRefGoogle Scholar
  5. 91.
    Joja I, Asakawa T, Mitsumori A, et al (1998) I-123 uptake in nonfunctional struma ovarii. Clin Nucl Med 23:10–12; Gershenson DM, Del Junco G, Silva EG, Copeland LJ, Wharton JT, Rutledge FN (1986) Immature teratoma of the ovary. Obstet Gynecol 68:624–629.Google Scholar
  6. 92.
    Hricak E (2007) Diagnostic imaging: Gynecology. AmirsysGoogle Scholar
  7. 93.
    Yamaoka T, Togashi K, Koyama T et al (2003) Immature teratoma of the ovary: correlation of MR imaging and pathologic findings. Eur Radiol 13:313–319PubMedGoogle Scholar
  8. 94.
    Favara BE, Franciosi RA (1973) Ovarian teratoma and neuroglial implants on the peritoneum. Cancer 31:678–681PubMedCrossRefGoogle Scholar
  9. 95.
    Miller DL, Pirani M (1984) Calcified intraperitoneal and mediastinal implants in malignant ovarian teratoma. J Can Assoc Radiol 35:217–219PubMedGoogle Scholar
  10. 96.
    Lentini JF, Love MB, Ritchie WG, Sedlacek TV (1986) Computed tomography in retroconversion of hepatic metastases from immature ovarian teratoma. J Comput Assist Tomogr 10:1060–1062PubMedCrossRefGoogle Scholar
  11. 97.
    Moskovic E, Jobling T, Fisher C, Wiltshaw E, Parsons C (1991) Retroconversion of immature teratoma of the ovary: CT appearances. Clin Radiol 43:402–408PubMedCrossRefGoogle Scholar
  12. 98.
    Logothetis CJ, Samuels ML, Trindade A, Johnson DE (1982) The growing teratoma syndrome. Cancer 50:1629–1635PubMedCrossRefGoogle Scholar
  13. 99.
    Gallion H, van Nagell JR, Donaldson ES, Hanson MB, Powell DF (1983) Immature teratoma of the ovary. Am J Obstet Gynecol 146:361–365PubMedGoogle Scholar
  14. 100.
    Thurlbeck WM, Scully RE (1960) Solid teratoma of the ovary. A clinicopathological analysis of 9 cases. Cancer 13:804–811PubMedCrossRefGoogle Scholar
  15. 101.
    Inakoa T, Takahashi K, Yamada T et al (2003) The growing teratoma syndrome secondary to immature teratoma of the ovary. Eur Radiol 13:2115–2118CrossRefGoogle Scholar

Mature Solid Teratoma

  1. 102.
    Kawakami S, Togashi K, Egawa H et al (1994) Solid mature teratoma of the ovary: appearances at MR imaging. Comput Med Imaging Graph 18:203–207PubMedCrossRefGoogle Scholar

Struma Ovarii

  1. 103.
    SzyfelbeinW M, Young RH, Scully RE (1995) Struma ovarii simulating ovarian tumors of other types. A report of 30 cases. Am J Surg Pathol 19:21–29CrossRefGoogle Scholar
  2. 104.
    Savelli L, Testa AC, Timmerman D, Paladini D, Lyungberg O, Valentin L (2008) Imaging of gynecological disease (4): clinical and ultrasound characteristics of struma ovarii. Ultrasound Obstet Gynecol 32(2):210–219PubMedCrossRefGoogle Scholar
  3. 105.
    Zalel Y, Seidman DS, Oren M et al (2000) Sonographic and clinical characteristics of struma ovarii. J Ultrasound Med 19:857–861PubMedGoogle Scholar
  4. 106.
    Zalel Y, Capsi B, Tepper R (1997) Doppler flow characteristics of dermoid cysts: unique appearance of struma ovarii. J Ultrasound Med 16:355–358PubMedGoogle Scholar
  5. 107.
    Matsumoto F, Yoshioka H, Hamada T, Ishida O, Noda K (1990) Struma ovarii: CT and MR findings. J Comput Assist Tomogr 14:310–312PubMedCrossRefGoogle Scholar
  6. 108.
    Van de Moortele K et al (2003) Struma ovarii: US and CT findings. JBR-BTR 86(4):209–210PubMedGoogle Scholar
  7. 109.
    Smith FG (1946) Pathology and physiology of struma ovarii. Arch Surg 53:603–626PubMedCrossRefGoogle Scholar
  8. 110.
    Hahn ST, Park SH, Bahk YW, Chung SK (1991) Struma ovarii simulating a teratodermoid cyst. Radiology 31:89–91Google Scholar
  9. 111.
    Joja I, Asakawa T, Mitsumori A et al (1998) Struma ovarii: appearance on MR images. Abdom Imaging 23:652–656PubMedCrossRefGoogle Scholar
  10. 112.
    Kim JC, Kim SS, Park JY (2000) MR findings of struma ovarii. Clin Imaging 24:28–33PubMedCrossRefGoogle Scholar
  11. 113.
    Dohke M, Watanabe Y, Takahashi A et al (1997) Struma ovarii: MR findings. J Comput Assist Tomogr 21:265–267PubMedCrossRefGoogle Scholar
  12. 114.
    Saito G, Mizutani K et al (1990) A struma ovarii with hyperthyroidism following resection. J Jap Plact Tokuda Surg Soc 51:396–398Google Scholar
  13. 115.
    Yamashita Y, Hatanaka Y, Takahashi M, Miyazaki K, Okamura H (1997) Struma ovarii: MR appearances. Abdom Imaging 22:100–102PubMedCrossRefGoogle Scholar
  14. 116.
    Okada S, Ohaki Y, Kawamura T, Hayashi T, Kumasaki T (2000) Cystic struma ovarii: imaging findings. J Comput Assist Tomogr 24(3):413–415PubMedCrossRefGoogle Scholar
  15. 117.
    Matsuki M, Kaji Y, Matsuo M, Kobashi Y (2000) Struma ovarii: MRI findings. Br J Radiol 73:87–90PubMedGoogle Scholar
  16. 118.
    Joja I, Asakawa T, Mitsumori A et al (1998) I-123 uptake in non functional struma ovarii. Clin Nucl Med 23:10–12PubMedCrossRefGoogle Scholar


  1. 119.
    Kleinman GM, Young RH, Scully RE (1993) Primary neuroectodermal tumors of the ovary. A report of 25 cases. Am J Surg Pathol 17:764–778PubMedCrossRefGoogle Scholar
  2. 120.
    Aguirre P, Scully RE (1982) Malignant neuroectodermal tumor of the ovary: a distinctive form of monodermal teratoma. Report of five cases. Am J Surg Pathol 6:283PubMedCrossRefGoogle Scholar
  3. 121.
    Kleinman GM, Young RH, Scully RE (1984) Ependymoma of the ovary: a report of three cases. Hum Pathol 15:632PubMedCrossRefGoogle Scholar

Primary Germ Cell Tumors

  1. 122.
    Meyer R (1931) The pathology of some special ovarian tumor and their relation to sex characteristics. Am J Obstet Gynecol 22:697Google Scholar
  2. 123.
    Adashi EY, Rock JA, Rosenwaks Z (1996) True hermaphroditism. In: Adashi EY, Rock JA, Rosenwaks Z (eds) Reproductive endocrinology, surgery and technology. Lippincott-Raven, Philadelphia/New York, pp 977–988Google Scholar


  1. 124.
    Dgani R, Shoham Z, Czernobilsky B, Kaftori A, Borenstein R, Lancet M (1988) Lactic dehydrogenase, alkaline phosphatase and human chorionic gonadotropin in a pure ovarian dysgerminoma. Gynecol Oncol 30:44–50PubMedCrossRefGoogle Scholar
  2. 125.
    Fujii S, Konishi I, Suzuki A, Okamura H, Okazaki T, Mori T (1985) Analysis of serum lactic dehydrogenase levels and its isoenzymes in ovarian dysgerminoma. Gynecol Oncol 22:65–72PubMedCrossRefGoogle Scholar
  3. 126.
    Pressley RH, Muntz HG, Falkenberry S, Rice LW (1992) Serum lactic dehydrogenase as a tumor marker in dysgerminoma. Gynecol Oncol 44:281–283PubMedCrossRefGoogle Scholar
  4. 127.
    Schwartz PE, Morris JM (1988) Serum lactic dehydrogenase: a tumor marker for dysgerminoma. Obstet Gynecol 72:511–515PubMedGoogle Scholar
  5. 128.
    Brammer HM, Buck JL, Hayes WS, Sheth S, Tavassoli FA (1990) From the archives of the AFIP. Malignant germ cell tumors of the ovary: radiologic-pathologic correlation. Radiographics 10:715–724PubMedGoogle Scholar
  6. 129.
    Tanaka YO, Kurosaki Y, Nishida M et al (1994) Ovarian dysgerminoma: MR and CT appearance. J Comput Assist Tomogr 18:443–448PubMedCrossRefGoogle Scholar
  7. 130.
    Gallion HH, van Nagell JR Jr, Donaldson ES, Powell DE (1988) Ovarian ­dysgerminoma: report of seven cases and review of the literature. Am J Obstet Gynecol 158:591–595PubMedGoogle Scholar
  8. 131.
    Markovits P, Bergiron C, Chauvel C, Castellino RA (1977) Lymphography in the staging, treatment planning, and surveillance of ovarian dysgerminomas. AJR Am J Roentgenol 128:835–838, JID – 7708173PubMedCrossRefGoogle Scholar
  9. 132.
    Parker M, Barnhill D, Teneriello M, O’Connor D, Park R (1992) Intestinal invasion by a dysgerminoma in a patient with Swyer syndrome. Obstet Gynecol 80:567–569PubMedGoogle Scholar
  10. 133.
    Takemori M, Ichimura T, Nishimura R, Hasegawa K (2000) Ovarian dysgerminoma with massive metastases to Para-aortic lymph nodes. Gynecol Obstet Invest 49:211–213PubMedCrossRefGoogle Scholar
  11. 134.
    Mueller CW, Topkins P, Lapp WA (1950) Dysgerminoma of the ovary: an analysis of 427 cases. Am J Obstet Gynecol 60:153–159PubMedGoogle Scholar
  12. 135.
    Sweetenham JW, Whitehouse JM, Williams CJ, Mead GM (1988) Involvement of the gastrointestinal tract by metastases from germ cell tumors of the testis. Cancer 61:2566–2570, JID – 0374236PubMedCrossRefGoogle Scholar
  13. 136.
    De Palo G, Pilotti S, Kenda R et al (1982) Natural history of dysgerminoma. Am J Obstet Gynecol 143:799–807, JID – 0370476PubMedGoogle Scholar
  14. 137.
    Schellhas HF, Trujillo JM, Rutledge FN, Cork A (1971) Germ cell tumors associated with XY gonadal dysgenesis. Am J Obstet Gynecol 109:1197–1204, JID – 0370476PubMedGoogle Scholar

Endodermal Sinus Tumor

  1. 138.
    Gershenson DM, Del Junco G, Herson J, Rutledge FN (1983) Endodermal sinus tumor of the ovary: the M. D. Anderson experience. Obstet Gynecol 61:194–202PubMedGoogle Scholar
  2. 139.
    Kawai M, Kano T, Furuhashi Y et al (1991) Prognostic factors in yolk sac tumors of the ovary. A clinicopathologic analysis of 29 cases. Cancer 67:184–192PubMedCrossRefGoogle Scholar
  3. 140.
    Kurman RJ, Norris HJ (1976) Endodermal sinus tumor of the ovary: a clinical and pathologic analysis of 71 cases. Cancer 38:2404–2419PubMedCrossRefGoogle Scholar
  4. 141.
    Langley FA, Govan AD, Anderson MC, Gowing NF, Woodcock AS, Harilal KR (1981) Yolk sac and allied tumours of the ovary. Histopathology 5:389–401PubMedCrossRefGoogle Scholar
  5. 142.
    Kawai M, Furuhashi Y, Kano T et al (1990) Alpha-fetoprotein in malignant germ cell tumors of the ovary. Gynecol Oncol 39:160–166PubMedCrossRefGoogle Scholar
  6. 143.
    Clement PB, Young RH, Scully RE (1987) Endometrioid-like variant of ovarian yolk sac tumor. A clinicopathological analysis of eight cases. Am J Surg Pathol 11:767–778PubMedCrossRefGoogle Scholar
  7. 144.
    Levitin A, Haller KD, Cohen HL, Zinn DL, O’Connor MT (1996) Endodermal sinus tumor of the ovary: imaging evaluation. AJR Am J Roentgenol 167:791–793PubMedCrossRefGoogle Scholar
  8. 145.
    Yamaoka T, Togashi K, Koyama T et al (2000) Yolk sac tumor of the ovary: radiologic-pathologic correlation in four cases. J Comput Assist Tomogr 24:605–609PubMedCrossRefGoogle Scholar
  9. 146.
    Kurman RJ, Norris HJ (1976) Endodermal sinus tumor of the ovary: a clinical and pathologic analysis of 71 cases. Cancer 38:2404–2419, JID – 0374236PubMedCrossRefGoogle Scholar
  10. 147.
    Huntington RWJ, Bullock WK (1970) Yolk sac tumors of the ovary. Cancer 25:1357–1367PubMedCrossRefGoogle Scholar
  11. 148.
    Jimerson GK, Woodruff JD (1977) Ovarian extraembryonal teratoma. I. Endodermal sinus tumor. Am J Obstet Gynecol 127:73–79PubMedGoogle Scholar
  12. 149.
    Talerman A, Haije WG, Baggerman L (1978) Serum alphafetoprotein (AFP) in diagnosis and management of endodermal sinus (yolk sac) tumor and mixed germ cell tumor of the ovary. Cancer 41:272–278PubMedCrossRefGoogle Scholar
  13. 150.
    Romero JA, Kim EE, Tresukosol D, Kudelka AP, Edwards CL, Kavanagh JJ (1995) Recurrent ovarian endodermal sinus tumor: demonstration by computed tomography, magnetic resonance imaging, and positron emission tomography. Eur J Nucl Med 22:1214–1217PubMedCrossRefGoogle Scholar


  1. 151.
    Bazot M, Cortez A, Sananes S, Buy JN (2004) Imaging of pure primary ovarian carcinoma. AJR Am J Roentgenol 182:1603–1604PubMedCrossRefGoogle Scholar

Embryonal Carcinoma

  1. 152.
    Neubecker RD, Breen JL (1962) Embryonal carcinoma of the ovary. Cancer 15:546PubMedCrossRefGoogle Scholar
  2. 153.
    Kurman RJ, Norris HJ (1976) Embryonal carcinoma of the ovary: a clinicopathologic entity distinct from endodermal sinus tumor resembling embryonal carcinoma of the adult testis. Cancer 38:2420–2433PubMedCrossRefGoogle Scholar

Mixed Germ Cell

  1. 154.
    Gershenson DM, Del Junco G, Copeland LJ, Rutledge FN (1984) Mixed germ cell tumors of the ovary. Obstet Gynecol 64:200–206PubMedGoogle Scholar
  2. 155.
    Kurman RJ, Norris HJ (1976) Malignant mixed germ cell tumors of the ovary. A clinical and pathologic analysis of 30 cases. Obstet Gynecol 48:579–589PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • Jean Noel Buy
    • 1
  • Michel Ghossain
    • 2
  1. 1.Service RadiologieHopital Hotel-DieuParisFrance
  2. 2.Department of RadiologyHotel Dieu de FranceBeirutLebanon

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