Modelling a DNA Walker

  • Thomas  E. Ouldridge
Part of the Springer Theses book series (Springer Theses)


The feet are intended to bind to adjacent sites on a single-stranded track. The binding sites overlap, meaning that the feet compete for binding to the track. As a consequence, a single-stranded region of one foot or the other is always exposed. A fuel strand that is also present in solution can bind to either exposed toehold.


Proximal Half Correct Binding Visual Argument Front Site Short Track 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    J. Bath et al. Mechanism for a directional, processive and reversible DNA motor. Small, 5:1513–1516, 2009.Google Scholar
  2. 2.
    J. SantaLucia, Jr. and D. Hicks. The thermodynamics of DNA structural motifs. Annu. Rev. Biophys. Biomol. Struct., 33:415–40, 2004.Google Scholar
  3. 3.
    B. Yurke and A. Mills. Using DNA to power nanostructures. Genetic Programming and Evolvable Machines, 4:111–122, 2003.Google Scholar
  4. 4.
    D.Y. Zhang and E. Winfree. Control of DNA strand displacement kinetics using toehold exchange. J. Am. Chem. Soc., 131(47):17303–17314, 2009.Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Thomas  E. Ouldridge
    • 1
  1. 1.University of OxfordOxfordUK

Personalised recommendations