Mouse-Induced Pluripotent Stem Cells
Pluripotent stem cells belong to a unique population of cells, which can self-renew indefinitely and have the potential to give rise to all cell types in an organism. Generally, pluripotent stem cells include embryonic stem cells (ESCs), embryonic germ cells (EGCs), and embryonal carcinoma cells (ECCs) (Boiani and Scholer 2005). In 2006, a new type of pluripotent stem cells, induced pluripotent stem cells (iPSCs), was established by direct reprogramming of differentiated somatic cells (Takahashi and Yamanaka 2006). The unique properties of iPSCs make them extremely attractive in regenerative medicine, drug screening, disease modeling, as well as study of developmental biology (Cyranoski 2008; Maherali and Hochedlinger 2008; Nishikawa et al. 2008).
KeywordsPluripotent Stem Cell Human ESCs iPSC Line Human iPSCs Starting Cell
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