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Physiologie der Befruchtung

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Zusammenfassung

Ziel der regelmäßig sich wiederholenden Abläufe des weiblichen Zyklus ist die Bereitstellung einer befruchtungsfähigen Oozyte in Synchronisation mit der Vorbereitung des Endometriums auf eine entstehende Schwangerschaft.

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Literatur

  • Avenarius MR et al. (2009) Human male infertility caused by mutations in the CATSPER1 channel protein. Am J Hum Genet 84 (4): 505–510

    Article  PubMed  CAS  Google Scholar 

  • Berridge MJ (2009) Inositol trisphosphate and calcium signalling mechanisms. Biochim Biophys Acta 1793: 933–940

    Article  PubMed  CAS  Google Scholar 

  • Bleil JD, Wassarman PM (1980) Mammalian sperm-egg interaction: identification of a glycoprotein in mouse egg zonae pellucidae possessing receptor activity for sperm. Cell 20 (3): 873–882

    Article  PubMed  CAS  Google Scholar 

  • Brunet S, Verlhac MH (2011) Positioning to get out of meiosis: the asymmetry of division. Hum Reprod Update 17 (1): 68–75

    Article  PubMed  Google Scholar 

  • Chang MC (1951) Fertilizing capacity of spermatozoa deposited into the fallopian tubes. Nature (London) 1951. 168 (4277): 697–698

    Article  CAS  Google Scholar 

  • De Jonge C (2005) Biological basis for human capacitation. Hum Reprod Update 11 (3): 205–214

    Article  PubMed  Google Scholar 

  • Dey SK (2010) How we are born. J Clin Invest 120 (4): 952–955

    Article  PubMed  CAS  Google Scholar 

  • Eichenlaub-Ritter U, Peschke M (2002) Expression in in-vivo and in-vitro growing and maturing oocytes: focus on regulation of expression at the translational level. Hum Reprod Update 8 (1): 21–41

    Article  PubMed  CAS  Google Scholar 

  • Fan HY et al. (2009) MAPK3/1 (ERK1/2) in ovarian granulosa cells are essential for female fertility. Science 324 (5929): 938–941

    Article  PubMed  CAS  Google Scholar 

  • Gahlay G et al. (2010) Gamete recognition in mice depends on the cleavage status of an egg’s zona pellucida protein. Science 329 (5988): 216–219

    Article  PubMed  CAS  Google Scholar 

  • Gianaroli L et al. (2010) Predicting aneuploidy in human oocytes: key factors which affect the meiotic process. Hum Reprod 25 (9): 2374–2386

    Article  PubMed  CAS  Google Scholar 

  • Gilchrist RB, Lane M, Thompson JG (2008) Oocyte-secreted factors: regulators of cumulus cell function and oocyte quality. Hum Reprod Update 14 (2): 159–177

    Article  PubMed  CAS  Google Scholar 

  • Gordo AC et al. (2002) Intracellular calcium oscillations signal apoptosis rather than activation in in vitro aged mouse eggs. Biol Reprod 66 (6): 1828–1837

    Article  PubMed  CAS  Google Scholar 

  • Gosden R, Lee B (2010) Portrait of an oocyte: our obscure origin. J Clin Invest 120 (4): 973–983

    Article  PubMed  CAS  Google Scholar 

  • Grant VJ, Chamley LW (2010) Can mammalian mothers influence the sex of their offspring peri-conceptually? Reproduction 140 (3): 425–433

    Article  PubMed  CAS  Google Scholar 

  • Huang Z, Wells D (2010) The human oocyte and cumulus cells relationship: new insights from the cumulus cell transcriptome. Mol Hum Reprod 16 (10): 715–725

    Article  PubMed  CAS  Google Scholar 

  • Ikawa M et al. (2010) Fertilization: a sperm’s journey to and interaction with the oocyte. J Clin Invest 120 (4): 984–994

    Article  PubMed  CAS  Google Scholar 

  • Inge GB, Brinsden PR, Elder KT (2005) Oocyte number per live birth in IVF: were Steptoe and Edwards less wasteful? Hum Reprod 20 (3): 588–592

    Article  PubMed  Google Scholar 

  • Kashir J Kashir J, Heindryckx B, Jones et al. (2010) Oocyte activation, phospholipase C zeta and human infertility. Hum Reprod Update 16 (6): 690–703

    Article  PubMed  CAS  Google Scholar 

  • Kimura M et al. (2009) Functional roles of mouse sperm hyaluronidases, HYAL5 and SPAM1, in fertilization. Biol Reprod 81 (5): 939–9347

    Article  PubMed  CAS  Google Scholar 

  • Litscher ES, Williams Z, Wassarman PM (2009) Zona pellucida glycoprotein ZP3 and fertilization in mammals. Mol Reprod Dev 76 (10): 933–941

    Article  PubMed  CAS  Google Scholar 

  • Market-Velker BA et al. (2010) Dual effects of superovulation: loss of maternal and paternal imprinted methylation in a dose-dependent manner. Hum Mol Genet 19 (1): 36–51

    Article  PubMed  CAS  Google Scholar 

  • Oren-Benaroya R et al. (2008) The sperm chemoattractant secreted from human cumulus cells is progesterone. Hum Reprod 23 (10): 2339–2345

    Article  PubMed  CAS  Google Scholar 

  • Otsuka F, McTavish KJ, Shimasaki S (2011) Integral role of GDF-9 and BMP-15 in ovarian function. Mol Reprod Dev 78 (1): 9–21

    Article  PubMed  CAS  Google Scholar 

  • Qiao J, Feng HL (2011) Extra- and intra-ovarian factors in polycystic ovary syndrome: impact on oocyte maturation and embryo developmental competence. Hum Reprod Update 17 (1): 17–33

    Article  PubMed  Google Scholar 

  • Richards JS, Pangas SA (2010) The ovary: basic biology and clinical implications. J Clin Invest 120 (4): 963–972

    Article  PubMed  CAS  Google Scholar 

  • Saunders CM et al. (2002) PLC zeta: a sperm-specific trigger of Ca (2+) oscillations in eggs and embryo development. Development 129 (15): 3533–3544

    PubMed  CAS  Google Scholar 

  • Sela-Abramovich S et al. (2005) Mitogen-activated protein kinase mediates luteinizing hormone-induced breakdown of communication and oocyte maturation in rat ovarian follicles. Endocrinology 146 (3): 1236–1244

    Article  PubMed  CAS  Google Scholar 

  • Smitz JE, Thompson JG, Gilchrist RB (2011) The promise of in vitro maturation in assisted reproduction and fertility preservation. Semin Reprod Med 29 (1): 24–37

    Article  PubMed  CAS  Google Scholar 

  • Su YQ et al. (2004) Synergistic roles of BMP15 and GDF9 in the development and function of the oocyte-cumulus cell complex in mice: genetic evidence for an oocyte-granulosa cell regulatory loop. Dev Biol 276 (1): 64–73

    Article  PubMed  CAS  Google Scholar 

  • Sun F et al. (2005) Human sperm chemotaxis: both the oocyte and its surrounding cumulus cells secrete sperm chemoattractants. Hum Reprod 20 (3): 761–767

    Article  PubMed  CAS  Google Scholar 

  • Sun QY, Miao YL, Schatten H (2009) Towards a new understanding on the regulation of mammalian oocyte meiosis resumption. Cell Cycle 8 (17): 2741–2747

    Article  PubMed  CAS  Google Scholar 

  • Sunkara SK et al. (2011) Association between the number of eggs and live birth in IVF treatment: an analysis of 400 135 treatment cycles. Hum Reprod 26 (7): 1768–1774

    Article  PubMed  Google Scholar 

  • Swain JE, Pool TB (2008) ART failure: oocyte contributions to unsuccessful fertilization. Hum Reprod Update 14 (5): 431–46

    Article  PubMed  Google Scholar 

  • Tripathi A Kumar KV, Chaube SK (2010) Meiotic cell cycle arrest in mammalian oocytes. J Cell Physiol 223 (3): 592–600

    PubMed  CAS  Google Scholar 

  • Visconti PE Florman HM (2010) Mechanisms of sperm-egg interactions: between sugars and broken bonds. Sci Signal 3 (142): pe35

    Article  Google Scholar 

  • Watson AJ (2007) Oocyte cytoplasmic maturation: a key mediator of oocyte and embryo developmental competence. J Anim Sci 85 (13 Suppl): E1–3

    Article  PubMed  CAS  Google Scholar 

  • Wilcox AJ CR Weinberg, Baird DD (1995) Timing of sexual intercourse in relation to ovulation. Effects on the probability of conception, survival of the pregnancy, and sex of the baby. N Engl J Med 333 (23): 1517–1521

    Article  PubMed  CAS  Google Scholar 

  • Yanagimachi R (2011) Mammalian sperm acrosome reaction: where does it begin before fertilization? Biol Reprod 85 (1): 4–5 [http://www.biolreprod.org/content/85/1/4.full.pdf+html]

  • Yeo CX et al. (2008) Exogenous growth differentiation factor 9 in oocyte maturation media enhances subsequent embryo development and fetal viability in mice. Human Reproduction 23 (1): 67–73

    Article  PubMed  CAS  Google Scholar 

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Sonntag, B. (2013). Physiologie der Befruchtung. In: Diedrich, K., Ludwig, M., Griesinger, G. (eds) Reproduktionsmedizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-30181-0_8

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  • DOI: https://doi.org/10.1007/978-3-642-30181-0_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-30180-3

  • Online ISBN: 978-3-642-30181-0

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