Skip to main content

LINDSAY Virtual Human: Multi-scale, Agent-based, and Interactive

  • Chapter

Part of the Studies in Computational Intelligence book series (SCI,volume 422)

Abstract

We are developing LINDSAY Virtual Human, a 3-dimensional, interactive computer model of male and female anatomy and physiology. LINDSAY is designed to be used for medical education. One key characteristic of LINDSAY is the integration of computational models across a range of spatial and temporal scales. We simulate physiological processes in an integrative fashion: from the body level to the level of organs, tissues, cells, and sub-cellular structures. For use in the classroom, we have built LINDSAY Presenter, a 3D slide-based visualization and exploration environment that presents different scenarios within the simulated human body. We are developing LINDSAY Composer to create complex scenes for demonstration, exploration and investigation of physiological scenarios. At LINDSAY Composer′s core is a graphical programming environment, which facilitates the composition of complex, interactive educational modules around the human body.

Keywords

  • Human Anatomy
  • Virtual Human
  • Virtual Body
  • Female Anatomy
  • Remote Control Application

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

This is a preview of subscription content, access via your institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • DOI: 10.1007/978-3-642-30154-4_14
  • Chapter length: 23 pages
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
eBook
USD   129.00
Price excludes VAT (USA)
  • ISBN: 978-3-642-30154-4
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book
USD   169.99
Price excludes VAT (USA)
Hardcover Book
USD   179.99
Price excludes VAT (USA)

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Entity systems are the future of MMOG development (September 2007), http://t-machine.org/index.php/2007/09/03/entity-systems-are-the-future-of-mmog-development-part-1

  2. Evolve your hierarchy (January 2007), http://cowboyprogramming.com/2007/01/05/evolve-your-heirachy

  3. Harvard BioVisions (January 2012), http://multimedia.mcb.harvard.edu

  4. Ackerman, M.J., Yoo, T., Jenkins, D.: From data to knowledge - the visible human project® continues. In: MEDINFO 2001, pp. 887–890 (2001)

    Google Scholar 

  5. Årzén, K., Bicchi, A., Dini, G., Hailes, S., Johanesson, K., Lygeros, J., Tzes, A.: A component-based approach to the design of networked control systems. European Journal of Control 13(2), 261–279 (2007)

    CrossRef  Google Scholar 

  6. Bauer, M., Bruegge, B., Klinker, G., MacWilliams, A., Reicher, T., Riß, S., Sandor, C., Wagner, M.: Design of a component-based augmented reality framework. In: International Symposium on Augmented Reality, Los Alamitos, CA, USA, p. 45 (2001)

    Google Scholar 

  7. Bonabeau, E., Dorigo, M., Theraulaz, G.: Swarm Intelligence: From Natural to Artificial Systems. Santa Fe Institute Studies in the Sciences of Complexity. Oxford University Press, New York (1999)

    MATH  Google Scholar 

  8. Burleigh, I., Suen, G., Jacob, C.: Dna in action! a 3d swarm-based model of a gene regulatory system. In: First Australian Conference on Artificial Life, ACAL 2003, Canberra, Australia (2003)

    Google Scholar 

  9. Camazine, S., Deneubourg, J.-L., Franks, N.R., Sneyd, J., Theraulaz, G., Bonabeau, E.: Self-Organization in Biological Systems. Princeton Studies in Complexity. Princeton University Press, Princeton (2003)

    MATH  Google Scholar 

  10. COLLADA.org. Collada - digital asset and fx exchange schema (April 2010), http://www.collada.org

  11. de Lara, E., Wallach, D.S., Zwaenepoel, W.: Puppeteer: Component-based adaptation for mobile computing. In: USENIX Symposium on Internet Technologies and Systems (2000)

    Google Scholar 

  12. Heineman, G.T., Councill, W.T.: Component-Based Software Engineering. ACM Press (2001)

    Google Scholar 

  13. Hoar, R., Penner, J., Jacob, C.: Transcription and evolution of a virtual bacteria culture. In: IEEE Congress on Evolutionary Computation. IEEE Press, Canberra (2003)

    Google Scholar 

  14. Hunter, P.J., Borg, T.K.: Integration from proteins to organs: the physiome project. Nature Reviews: Molecular Cell Biology 4, 237–243 (2003)

    CrossRef  Google Scholar 

  15. Jacob, C., Barbasiewicz, A., Tsui, G.: Swarms and genes: Exploring λ-switch gene regulation through swarm intelligence. In: IEEE Congress on Evolutionary Computation, CEC 2006 (2006)

    Google Scholar 

  16. Jacob, C., Burleigh, I.: Biomolecular swarms: An agent-based model of the lactose operon. Natural Computing 3(4), 361–376 (2004)

    MathSciNet  CrossRef  Google Scholar 

  17. Johnson, S.: Emergence: The Connected Lives of Ants, Brains, Cities, and Software. Scribner, New York (2001)

    Google Scholar 

  18. Leavens, G.T., Sitaraman, M. (eds.): Foundations of component-based systems. Cambridge University Press, New York (2000)

    MATH  Google Scholar 

  19. Lewandowski, S.M.: Frameworks for component-based client server computing. ACM Comput. Surv. 30(1), 3–27 (1998)

    CrossRef  Google Scholar 

  20. Mikic-Rakic, M., Malek, S., Medvidovic, N.: Improving availability in large, distributed component-based systems via redeployment. Component Deployment, 83–98 (2005)

    Google Scholar 

  21. Mitsuhashi, N., Fujieda, K., Tamura, T., Kawamoto, S., Takagi, T., Okubo, K.: BodyParts 3D: 3D structure database for anatomical concepts. Nucl. Acids Res. (2008), gkn613

    Google Scholar 

  22. N. L. of Medicine. National library of medicine: The visible human project (April 2010), http://www.nlm.nih.gov/research/visible/visible_human.html

  23. Penner, J., Hoar, R., Jacob, C.: Bacterial chemotaxis in silico. In: First Australian Conference on Artificial Life, ACAL 2003, Canberra, Australia (2003)

    Google Scholar 

  24. Pogson, M., Smallwood, R., Qwarnstrom, E., Holcomb, M.: Formal agent-based modelling of intracellular chemical interactions. BioSystems (2006)

    Google Scholar 

  25. Roussain, H., Guidec, F.: Cooperative component-based software deployment in wireless ad hoc networks. Component Deployment, 1–16 (2005)

    Google Scholar 

  26. Seifert, M.F.: Visible human projects special issue. Clinical Anatomy 19(3), 191–289 (2010)

    CrossRef  Google Scholar 

  27. Sensen, C.W., Soh, J.: CAVEman, An Object-Oriented Model of the Human Body. In: Sensen, C.W., Soh, J. (eds.) Advanced Imaging in Biology and Medicine, vol. II, pp. 289–300. Springer, Heidelberg (2009)

    CrossRef  Google Scholar 

  28. Stoy, C.: Game Object Component System. In: Game Programming Gems 6, pp. 393–403. Charles River Media (2006)

    Google Scholar 

  29. Tietze, D. A.: A Framework for Developing Component-based Co-operative Applications. PhD thesis, Technische Universität Darmstadt, Darmstadt, Germany (2000)

    Google Scholar 

  30. von Mammen, S., Davison, T., Baghi, H., Jacob, C.: Component-based networking for simulations in medical education. In: MediaWiN 2010: IEEE Workshop on Multimedia Applications Over Wireless Networks, Riccione, Italy. IEEE Computer Society, IEEE Press, Washington (2010)

    Google Scholar 

  31. Walker, D.C., Southgate, J.: The virtual cell–a candidate co-ordinator for ’middle-out’ modelling of biological systems. Briefings in Bioinformatics 10(4), 450–461 (2009)

    CrossRef  Google Scholar 

  32. Wilson, K.: Game object structure: Inheritance vs aggregation (July 2002)

    Google Scholar 

  33. Wolfram, S.: A new kind of science. Wolfram Media Inc., Champaign (2002)

    MATH  Google Scholar 

  34. Yazdanbod, I., Marcus, S.: An agent-based simulation of blood coagulation processes. The Journal of Undergraduate Research in Alberta 1(1), 13–18 (2010)

    Google Scholar 

  35. Zygote Inc. Zygote human anatomy 3d model (April 2010), http://www.zygote.com

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to C. Jacob .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and Permissions

Copyright information

© 2012 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Jacob, C. et al. (2012). LINDSAY Virtual Human: Multi-scale, Agent-based, and Interactive. In: Kołodziej, J., Khan, S., Burczy´nski, T. (eds) Advances in Intelligent Modelling and Simulation. Studies in Computational Intelligence, vol 422. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-30154-4_14

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-30154-4_14

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-30153-7

  • Online ISBN: 978-3-642-30154-4

  • eBook Packages: EngineeringEngineering (R0)