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A Model for Biased Fractionation after Whole Genome Duplication

  • David Sankoff
  • Chunfang Zheng
  • Baoyong Wang
Part of the Lecture Notes in Computer Science book series (LNCS, volume 7262)

Abstract

Paralog reduction, the loss of duplicate genes after whole genome duplication (WGD), causes more gene order disruption than chromosomal rearrangements such as inversion or translocation. This is particularly true in flowering plants.

Whether the loss proceeds gene by gene or through deletion of multi-gene DNA segments is controversial, as is the question of fractionation bias, namely whether one of the two homeologous chromosomes is more vulnerable to deletion. The process is subject to the overriding functional constraint that only one gene copy can be deleted.

Keywords

Null Hypothesis Gene Copy Main Part Variable Number Problem Complexity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • David Sankoff
    • 1
  • Chunfang Zheng
    • 1
  • Baoyong Wang
    • 1
  1. 1.Department of Mathematics and StatisticsUniversity of OttawaCanada

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