Palliative Radiation for Brain Metastases

  • David C. Weksberg
  • Jiade J. Lu
  • Eric L. Chang


The brain is one of the most common sites of cancer metastasis, and radiation, in conjunction with surgery and steroid therapy, is a cornerstone of management of brain metastases. Whole brain radiation therapy (WBRT) using conventional external beam radiation is most commonly employed. Stereotactic radiosurgery (SRS) can be used in the adjuvant or upfront settings for patients with limited number of intracranial metastatic foci, sufficient extracranial disease control, and appropriate performance status.


Brain Metastasis Gross Tumor Volume Gamma Knife Whole Brain Radiation Therapy Stereotactic Radiosurgery 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • David C. Weksberg
    • 1
  • Jiade J. Lu
    • 2
    • 3
  • Eric L. Chang
    • 4
  1. 1.Department of Radiation OncologyUniversity of Texas MD Anderson Cancer CenterHoustonUSA
  2. 2.Department of Radiation OncologyNational University Cancer Institute, National University Health SystemSingaporeSingapore
  3. 3.Department of Medicine, School of MedicineNational University of SingaporeSingaporeSingapore
  4. 4.Department of Radiation OncologyUniversity of Southern California Keck School of Medicine, Norris Cancer HospitalLos AngelesUSA

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