Non-small Cell Lung Cancer (NSCLC) and Small Cell Lung Cancer (SCLC)

  • Daniel R. Gomez
  • Zhongxing Liao


Computed tomography (CT)-based planning utilizing conformal techniques is the standard of care for NSCLC and SCLC. Three-dimensional conformal radiation therapy (3D-CRT) and intensity-modulated radiation therapy (IMRT) both involve the utilization of a number of beam angles and the generation of a dosevolume histogram.


Small Cell Lung Cancer Plan Target Volume Clinical Target Volume Stereotactic Body Radiation Therapy Gross Tumor Volume 
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  1. 1.
    Chapet O, Kong FM, Quint LE et al (2005) CT-based definition of thoracic lymph node s­tations: an atlas from the University of Michigan. Int J Radiat Oncol Biol Phys 63:170–178PubMedCrossRefGoogle Scholar
  2. 2.
    Kong FM, Ritter T, Quint DJ et al (2011) Consideration of dose limits for organs at risk of thoracic radiotherapy: atlas for lung, proximal bronchial tree, esophagus, spinal cord, ribs, and brachial plexus. Int J Radiat Oncol Biol Phys 81(5):1442–1457PubMedCrossRefGoogle Scholar
  3. 3.
    Rosenzweig KE, Sim SE, Mychalczak B et al (2001) Elective nodal irradiation in the treatment of non-small-cell lung cancer with three-dimensional conformal radiation therapy. Int J Radiat Oncol Biol Phys 50:681–685PubMedCrossRefGoogle Scholar
  4. 4.
    Rosenzweig KE, Sura S, Jackson A et al (2007) Involved-field radiation therapy for inoperable non small-cell lung cancer. J Clin Oncol 25:5557–5561PubMedCrossRefGoogle Scholar
  5. 5.
    Yuan S, Sun X, Li M et al (2007) A randomized study of involved-field irradiation versus elective nodal irradiation in combination with concurrent chemotherapy for inoperable stage III nonsmall cell lung cancer. Am J Clin Oncol 30:239–244PubMedCrossRefGoogle Scholar
  6. 6.
    Giraud P, Antoine M, Larrouy A et al (2000) Evaluation of microscopic tumor extension in non-small-cell lung cancer for three-dimensional conformal radiotherapy planning. Int J Radiat Oncol Biol Phys 48:1015–1024PubMedCrossRefGoogle Scholar
  7. 7.
    Spoelstra FO, Senan S, Le Pechoux C et al (2009) Variations in target volume definition for postoperative radiotherapy in stage III non-small-cell lung cancer: analysis of an international contouring study. Int J Radiat Oncol Biol Phys 76:1106–1113PubMedCrossRefGoogle Scholar
  8. 8.
    Jeremic B, Shibamoto Y, Nikolic N et al (1999) Role of radiation therapy in the combined-modality treatment of patients with extensive disease small-cell lung cancer: a randomized study. J Clin Oncol 17:2092–2099PubMedGoogle Scholar
  9. 9.
    Marks LB, Yorke ED, Jackson A et al (2010) Use of normal tissue complication probability models in the clinic. Int J Radiat Oncol Biol Phys 76:S10–S19PubMedCrossRefGoogle Scholar
  10. 10.
    American Joint Committee (2010) Cancer staging manual, 7th edn. Springer, New YorkGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  1. 1.Department of Radiation OncologyUniversity of Texas MD Anderson Cancer CenterHoustonUSA

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