A Rare Disease Patient Manager

  • Pedro Lopes
  • Rafael Mendonça
  • Hugo Rocha
  • Jorge Oliveira
  • Laura Vilarinho
  • Rosário Santos
  • José Luís Oliveira
Part of the Advances in Intelligent and Soft Computing book series (AINSC, volume 154)

Abstract

The personal health implications behind rare diseases are seldom considered in widespread medical care. The low incidence rate and complex treatment process makes rare disease research an underrated field in the life sciences. However, it is in these particular conditions that the strongest relations between genotypes and phenotypes are identified. The rare disease patient manager, detailed in this manuscript, presents an innovative perspective for a patient-centric portal integrating genetic and medical data. With this strategy, patient’s digital records are transparently integrated and connected to wet-lab genetics research in a seamless working environment. The resulting knowledge base offers multiple data views, geared towards medical staff, with patient treatment and monitoring data; genetics researchers, through a custom locus-specific database; and patients, who for once play an active role in their treatment and rare diseases research.

Keywords

Rare Diseases Genetic Mutations LSDB Personalized Medicine 

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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Pedro Lopes
    • 1
  • Rafael Mendonça
    • 1
  • Hugo Rocha
    • 2
  • Jorge Oliveira
    • 2
  • Laura Vilarinho
    • 2
  • Rosário Santos
    • 2
  • José Luís Oliveira
    • 1
  1. 1.DETI/IEETAUniversidade de AveiroAveiroPortugal
  2. 2.Centro de Genética Médica Jacinto MagalhãesINSAPortoPortugal

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