Complications of Mesotherapy

  • Doris M. Hexsel
  • Juliana Dumêt Fernandes


Treatment modalities for cellulite, localized fat, and other cosmetic conditions have proliferated over the last several years. With the escalating demand for noninvasive cosmetic procedures, mesotherapy have attracted interest from physicians and the general public.


Degenerative Disc Disease Body Contour Intermenstrual Bleeding Postinflammatory Hyperpigmentation Atypical Mycobacterial Infection 
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  1. 1.
    Alam M, Dover JS (2008) Non-surgical skin tightening and lifting. Procedures in cosmetic dermatology. Elsevier Health Sciences, PhiladelphiaGoogle Scholar
  2. 2.
    Avram MM (2005) Cellulite: a review of its physiology and treatment. J Cosmet Laser Ther 7:18Google Scholar
  3. 3.
    Bessis D, Guilhou JJ, Guillot B (2004) Localized urticaria pigmentosa triggered by mesotherapy. Dermatology 209(4):343–344PubMedCrossRefGoogle Scholar
  4. 4.
    Brandao C, Fernandes N, Mesquita N et al (2005) Abdominal haematoma – a mesotherapy complication. Acta Derm Venereol 85(5):446PubMedGoogle Scholar
  5. 5.
    Centers for Disease Control and Prevention (CDC) (2005) Outbreak of mesotherapy-associated skin reactions-District of Columbia area, January-February 2005. MMWR Morb Mortal Wkly Rep 54(44):1127–1130Google Scholar
  6. 6.
    Correa NE, Cataño JC, Mejía GI et al (2010) Outbreak of mesotherapy-associated cutaneous infections caused by Mycobacterium chelonae in Colombia. Jpn J Infect Dis 63(2):143–145PubMedGoogle Scholar
  7. 7.
    Da Mata Jardín O, Hernández-Pérez R, Corrales H et al (2010) Follow-up of an outbreak of Mycobacterium abscessus soft-tissue infection associated with mesotherapy in Venezuela. Enferm Infecc Microbiol Clin 28(9):596–601PubMedCrossRefGoogle Scholar
  8. 8.
    Danilovic DL, Bloise W, Knobel M, Marui S (2008) Factitious thyrotoxicosis induced by mesotherapy: a case report. Thyroid 18(6):655–657PubMedCrossRefGoogle Scholar
  9. 9.
    Food and Drug Administration (1996) Current good manufacturing practice for finished pharmaceuticals. US Department of Health and Human Services, Food and Drug Administration, Rockville, Available at: Google Scholar
  10. 10.
    Gutiérrez-de la Peña J, Ruiz-Veramendi M, Montis-Suau A, Martín-Santiago A (2010) Three cases of panniculitis due to Mycobacterium abscessus after mesotherapy. Actas Dermosifiliogr 101(2):188–190PubMedCrossRefGoogle Scholar
  11. 11.
    Kim JB, Moon W, Park SJ et al (2010) Ischemic colitis after mesotherapy combined with anti-obesity medications. World J Gastroenterol 16(12):1537–1540PubMedCrossRefGoogle Scholar
  12. 12.
    Lee DP, Chang SE (2005) Subcutaneous nodules showing fat necrosis owing to mesotherapy. Dermatol Surg 31:250–251PubMedGoogle Scholar
  13. 13.
    Matarasso A, Pfeifer TM (2005) Plastic surgery educational foundation DATA committee. Mesotherapy for body contouring. Plast Reconstr Surg 115:1420–1424PubMedCrossRefGoogle Scholar
  14. 14.
    Nagore E, Ramos P, Botella Estrada R et al (2001) Cutaneous infection with Mycobacterium fortuitum after localized microinjections (Mesotherapy) treated successfully with a triple drug regimen. Acta Derm Venereol 81:291–293PubMedCrossRefGoogle Scholar
  15. 15.
    Rose PT, Morgan M (2005) Histological changes associated with mesotherapy for fat dissolution. J Cosmet Laser Ther 7:17–19PubMedCrossRefGoogle Scholar
  16. 16.
    Rosina P, Chieregato C, Miccolis D, D’Onghia FS (2001) Psoriasis and side-effects of mesotherapy. Int J Dermatol 40:581–583PubMedCrossRefGoogle Scholar
  17. 17.
    Rotunda AM, Kolodney MS (2006) Mesotherapy and phosphatidylcholine injections: historical clarification and review. Dermatol Surg 32(4):465–480PubMedCrossRefGoogle Scholar
  18. 18.
    Rotunda AM, Avram MM, Avram AS (2005) Cellulite: is there a role for injectables? J Cosmet Laser Ther 7(3–4):147–154PubMedCrossRefGoogle Scholar
  19. 19.
    Rotunda AM, Suzuki H, Moy RL, Kolodney MS (2004) Detergent effects of sodium deoxycholate are a major feature of an injectable phosphatidyl choline formulation used for localized fat dissolution. Dermatol Surg 30:1001–1008PubMedCrossRefGoogle Scholar
  20. 20.
    Tan J, Rao B (2006) Mesotherapy-induced panniculitis treated with dapsone: case report and review of reported adverse effects of mesotherapy. J Cutan Med Surg 10(2):92–95PubMedGoogle Scholar
  21. 21.
    Vedamurthy M (2007) Mesotherapy. Indian J Dermatol Venereol Leprol 73(1):60–62PubMedCrossRefGoogle Scholar
  22. 22.
    Wanner M, Avram M (2008) An evidence-based assessment of treatments for cellulite. J Drugs Dermatol 7(4):341–345PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  1. 1.Department of DermatologyPontificia Universidade Catolica do Rio Grande do SulPorto AlegreBrazil
  2. 2.Department of DermatologyUniversity of São PauloSão PauloBrazil

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