Abstract
Cutaneous nevogenesis is largely considered a localized event that occurs exclusively in the dermis and/or epidermis. However, the presence of circulating nevocytes suggests that other, more systemic, benign metastatic processes could also contribute to nevogenesis. The theoretical role of lymphatic and hematogenous dissemination of loosely adherent, immature nevus progenitor cells in the development of nodal nevi and eruptive melanocytic nevi will be reviewed.
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Conflict of Interest
DigitalDerm, Inc – major shareholder. Spectral Image, Inc – past grants and consulting. MELA Sciences, Inc – past grants and consulting. Genentech – consultant. Archives of Dermatology, skINsight – section editor.
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Ross, A.L., Sanchez, M.I., Grichnik, J.M. (2012). Nevogenesis: A Benign Metastatic Process?: An Update. In: Marghoob, A. (eds) Nevogenesis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-28397-0_9
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DOI: https://doi.org/10.1007/978-3-642-28397-0_9
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