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Nevogenesis pp 59-67 | Cite as

Confocal Microscopy: Improving Our Understanding of Nevogenesis

  • Barbara De Pace
  • Barbara Ferrari
  • Giovanni Pellacani
  • Barbara Predieri
  • Lorenzo Iughetti
  • Leonardo Veneziano
  • Iris Zalaudek
  • Giuseppe Argenziano
  • Caterina Longo
Chapter

Abstract

Nevi are benign clonal proliferations of cells expressing a melanocytic phenotype. The development of melanocytic nevi is a complex, multifactorial process. In some conditions, it has been demonstrated that genetic factors (i.e., numerical and structural abnormalities of chromosomes, mutant genes, genetic mosaic) or environmental factors (i.e., intrauterine infections, ionizing radiation, drugs, alcohol, deficiency or excess of trace elements in pregnancy, maternal diseases) or combinations of both may play a role. However, in almost all cases the etiology remains unknown.

Keywords

Dermal Papilla Melanocytic Nevus Melanocytic Lesion Reflectance Confocal Microscopy Nevus Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer- Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Barbara De Pace
    • 1
  • Barbara Ferrari
    • 1
  • Giovanni Pellacani
    • 1
  • Barbara Predieri
    • 2
  • Lorenzo Iughetti
    • 2
  • Leonardo Veneziano
    • 3
    • 4
  • Iris Zalaudek
    • 5
    • 6
  • Giuseppe Argenziano
    • 7
  • Caterina Longo
    • 7
  1. 1.Department of DermatologyUniversity of Modena and Reggio EmiliaModenaItaly
  2. 2.Department of PediatricsUniversity of Modena and Reggio EmiliaModenaItaly
  3. 3.Dermatology UnitAUSL Bologna – Ospedale Bellaria MaggioreBolognaItaly
  4. 4.Department of DermatologyUniversity of Modena and Reggio EmiliaBologna ModenaItaly
  5. 5.Department of DermatologyMedical University of GrazGrazAustria
  6. 6.Department of DermatologyArcispedale Santa Maria Nuova, IRCCSReggio EmiliaItaly
  7. 7.Dermatology and Skin Cancer UnitArcispedale Santa Maria Nuova, IRCCSReggio EmiliaItaly

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