Variability of the Human Cardiac Laminar Structure

  • Hervé Lombaert
  • Jean-Marc Peyrat
  • Laurent Fanton
  • Farida Cheriet
  • Hervé Delingette
  • Nicholas Ayache
  • Patrick Clarysse
  • Isabelle Magnin
  • Pierre Croisille
Part of the Lecture Notes in Computer Science book series (LNCS, volume 7085)


The cardiac fiber architecture has an important role in electrophysiology, in mechanical functions of the heart, and in remodeling processes. The variability of the fibers is the focus of various studies in different species. However, the variability of the laminar sheets is still not well known especially in humans. In this paper, we present preliminary results on a quantitative study on the variability of the human cardiac laminar structure. We show that the laminar structure has a complex variability and we show the possible presence of two populations of laminar sheets. Bimodal distributions of the intersection angle of the third eigenvector of the diffusion tensor have been observed in 10 ex vivo healthy human hearts. Additional hearts will complete the study and further characterize the different populations of cardiac laminar sheets.


Intersection Angle Joint Histogram Horizontal Curf Laminar Sheet Tensor Magnetic Resonance Image 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Hervé Lombaert
    • 1
    • 2
  • Jean-Marc Peyrat
    • 4
  • Laurent Fanton
    • 3
  • Farida Cheriet
    • 2
  • Hervé Delingette
    • 1
  • Nicholas Ayache
    • 1
  • Patrick Clarysse
    • 3
  • Isabelle Magnin
    • 3
  • Pierre Croisille
    • 3
  1. 1.INRIA, Asclepios TeamSophia-AntipolisFrance
  2. 2.École Polytechnique de MontréalCanada
  3. 3.CREATIS, Université de LyonFrance
  4. 4.Siemens MolecularOxfordUK

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