Defining acute renal failure: physiological principles

  • Rinaldo Bellomo
  • John A. Kellum
  • Claudio Ronco
Chapter

Abstract

Definitions are never “right” or “wrong”. They are simply more or less “useful” for a given purpose. The same is true of the clinical syndrome of acute renal failure (ARF), which is common in the ICU [1, 2]. In many ways, its nature and epidemiology resemble those of other loosely defined ICU syndromes, such as sepsis or ARDS. In this physiological note, however, we wish to focus on how our understanding of renal physiology can be used to guide the definition of ARF.

Keywords

Acute Renal Failure Renal Mass Serum Cystatin Normal Glomerular Filtration Rate Baseline Glomerular Filtration Rate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Rinaldo Bellomo
    • 1
  • John A. Kellum
    • 2
  • Claudio Ronco
    • 3
  1. 1.Department of Intensive Care and Division of SurgeryAustin & Repatriation Medical CentreMelbourneAustralia
  2. 2.Division of Critical Care Medicine, Scaife HallUniversity of Pittsburgh Medial CentrePittsburghUSA
  3. 3.Divisione di Nefrologia, Ospedale San BortoloVicenzaItaly

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