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Magnesium in critical illness: metabolism, assessment, and treatment

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Abstract

Magnesium is the second most abundant intracellular cation and the fourth most common cation in the body [1]. Its importance as an essential nutrient has been recognized since 1932, when Kruse et al. [2] reported the effects of acute Mg deficiency in rats. Even recently Mg was considered the “forgotten cation” in clinical practice [3]; however, this is no longer the case [4]. Estimates of Mg deficiency range from 20% to 61% [5, 6, 7], while a recent study found that reductions in total serum Mg on admission are associated with increased mortality [8].

Keywords

  • Critical Illness
  • Magnesium Deficiency
  • Acute Intermittent Porphyria
  • Massive Blood Transfusion
  • Intracellular Magnesium

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Noronha, L.J., Matuschak, G.M. (2012). Magnesium in critical illness: metabolism, assessment, and treatment. In: Pinsky, M.R., Brochard, L., Mancebo, J., Antonelli, M. (eds) Applied Physiology in Intensive Care Medicine 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-28233-1_8

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