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Applied Physiology in Intensive Care Medicine 2 pp 71–83Cite as

Magnesium in critical illness: metabolism, assessment, and treatment

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Abstract

Magnesium is the second most abundant intracellular cation and the fourth most common cation in the body [1]. Its importance as an essential nutrient has been recognized since 1932, when Kruse et al. [2] reported the effects of acute Mg deficiency in rats. Even recently Mg was considered the “forgotten cation” in clinical practice [3]; however, this is no longer the case [4]. Estimates of Mg deficiency range from 20% to 61% [5, 6, 7], while a recent study found that reductions in total serum Mg on admission are associated with increased mortality [8].

Keywords

  • Critical Illness
  • Magnesium Deficiency
  • Acute Intermittent Porphyria
  • Massive Blood Transfusion
  • Intracellular Magnesium

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Authors and Affiliations

  1. Division of Pulmonary, Critical Care and Occupational Medicine, Departments of Internal Medicine and Pharmacological and Physiological Science, School of Medicine, Saint Louis University, Saint Louis, MO, USA

    Luis J. Noronha & George M. Matuschak

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  1. Luis J. Noronha
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  2. George M. Matuschak
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Editors and Affiliations

  1. Dept. of Critical Care Medicine, University of Pittsburgh Medical Center, Scaife Hall 606 3550 Terrace Street, Pittsburgh, PA, 15261, USA

    Michael R. Pinsky MD

  2. Dept. Intensive Care Medicine, Hôpital Henri Mondor, 51 av. Maréchal Lattre de Tassigny, 94010, Créteil, CX, France

    Laurent Brochard MD

  3. Dept. Intensive Care Medicine, Hospital de Sant Pau, Avda. S. Antonio M. Claret 167, 08025, Barcelona, Spain

    Jordi Mancebo MD

  4. General Intensive Care Unit, Università Cattolica des Sacro Cuore, Largo A. Gemelli 8, 00168, Rome, Italy

    Massimo Antonelli

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Noronha, L.J., Matuschak, G.M. (2012). Magnesium in critical illness: metabolism, assessment, and treatment. In: Pinsky, M.R., Brochard, L., Mancebo, J., Antonelli, M. (eds) Applied Physiology in Intensive Care Medicine 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-28233-1_8

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