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Applied Physiology in Intensive Care Medicine 2 pp 383–384Cite as

The hidden pulmonary dysfunction in acute lung injury

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Abstract

In the Intensive Care Medicine Aboab and coworkers [1] now show that the use of 100% O2 in inspired gas at low levels of positive end-expiratory pressure (PEEP 5 cmH2O) promotes lung collapse and impedes gas exchange in patients with acute lung injury. The collapse could be prevented or at least countered during the 30min study period by higher levels of PEEP (15 cmH2O). What do we learn from this?

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Author information

Authors and Affiliations

  1. Clinical Physiology, Department of Medical Sciences, University Hospital, Uppsala, Sweden

    Göran Hedenstierna

Authors
  1. Göran Hedenstierna
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Editor information

Editors and Affiliations

  1. Dept. of Critical Care Medicine, University of Pittsburgh Medical Center, Scaife Hall 606 3550 Terrace Street, Pittsburgh, PA, 15261, USA

    Michael R. Pinsky MD

  2. Dept. Intensive Care Medicine, Hôpital Henri Mondor, 51 av. Maréchal Lattre de Tassigny, 94010, Créteil, CX, France

    Laurent Brochard MD

  3. Dept. Intensive Care Medicine, Hospital de Sant Pau, Avda. S. Antonio M. Claret 167, 08025, Barcelona, Spain

    Jordi Mancebo MD

  4. General Intensive Care Unit, Università Cattolica des Sacro Cuore, Largo A. Gemelli 8, 00168, Rome, Italy

    Massimo Antonelli

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© 2012 Springer-Verlag Berlin Heidelberg

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Hedenstierna, G. (2012). The hidden pulmonary dysfunction in acute lung injury. In: Pinsky, M.R., Brochard, L., Mancebo, J., Antonelli, M. (eds) Applied Physiology in Intensive Care Medicine 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-28233-1_47

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  • DOI: https://doi.org/10.1007/978-3-642-28233-1_47

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-28232-4

  • Online ISBN: 978-3-642-28233-1

  • eBook Packages: MedicineMedicine (R0)

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