Variability of splanchnic blood flow measurements in patients with sepsis – physiology, pathophysiology or measurement errors?

  • S. M. Jakob
  • J. Takala


Impaired tissue oxygenation, especially in the splanchnic region, may play a central role both in the pathogenesis of multiple organ dysfunction and in the development of complications in various groups of intensive care patients [1, 2]. In severe inflammation such as SIRS, septic infection, and septic shock, the metabolic demand for oxygen in the splanchnic region is increase [3, 4, 5]. This is explanied in part by and increased hepatic metabolism [6, 7]. In patients with normal or hyperdynamic hemodynamics, but the increase in oxygen consumption is disproportionate to the increase in blood flow.


Septic Shock Heart Rate Variability Indocyanine Green Splanchnic Blood Flow Splanchnic Perfusion 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • S. M. Jakob
    • 1
  • J. Takala
    • 2
  1. 1.Department of Intensive Care MedicineUniversity Hospital BernBernSwitzerland
  2. 2.Department of Intensive Care MedicineUniversity Hospital Bern (Inselspital), University of BernBernSwitzerland

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