• Jens Jakob Riis


Corticosteroids to brain trauma patients have for a long time been an important and controversial topic; so far, there has not been consensus regarding the possible benefits or adverse effects of administration of corticosteroids to such patients. High-dose methylprednisolone to patients with trauma-induced spinal transection has been abandoned in many Nordic trauma centres due to (1) lack of evidence for beneficial effect, (2) harmful effect on brain trauma patients with spinal cord injuries, and (3) the significant side effects, e.g. hyperglycaemia, gastric ulcers/bleeding, increased risk of infection, psychosis and impairment of wound healing (Poungvarin 2004).


Spinal Cord Injury Trauma Patient Brain Oedema Controversial Topic Significant Side Effect 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  1. 1.Department of NeurosurgeryAarhus Aaarhus University HospitalAarhusDenmark

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