Prophylaxis Against Venous Thromboembolism in Patients with Traumatic Brain Injury
Patients with severe traumatic brain injury (TBI) are at significant risk of developing venous thromboembolic complications. The risk has been estimated to 20% in the absence of any prophylaxis (Knudson et al. 2004). Another review found an estimated risk of pulmonary embolism (PE) of 0.38% among patients with severe TBI (Page et al. 2004). Unfortunately, we only have publications supporting Level III evidence in this high risk population of trauma patients.
KeywordsTraumatic Brain Injury Pulmonary Embolism Trauma Patient Central Venous Pressure Intracranial Bleeding
- Turpie AG, Hirsh J, Gent M et al (1989) Prevention of deep vein thrombosis in potential neurosurgical patients. A randomized trial comparing graduated compression stockings alone or graduated compression stockings plus intermittent compression with control. Arch Intern Med 149:679–681PubMedCrossRefGoogle Scholar