• Anne Berit Guttormsen
  • Bram de Hoog
  • Jennie Hernæs


Individual nutritional support is an important component in all patient care and might contribute to better outcome and optimal rehabilitation (Singer et al. 2011). Hyperglycaemia is associated with worse outcome, and serum glucose of 6–9 mmol/l seems optimal (Bechir et al. 2010; Meierhans et al. 2010; Kansagara et al. 2011).


Parenteral Nutrition Enteral Nutrition Nitrogen Balance Indirect Calorimetry Rest Energy Expenditure 
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  1. Bechir M, Meierhans R, Brandi G, Sommerfeld J, Fasshauer M, Cottini SR, Stocker R, Stover JF (2010) Insulin differentially influences brain glucose and lactate in traumatic brain injured patients. Minerva Anestesiol 76:896–904PubMedGoogle Scholar
  2. Boivin MA, Levy H (2001) Gastric feeding with erythromycin is equivalent to transpyloric feeding in the critically ill. Crit Care Med 29:1916–1919PubMedCrossRefGoogle Scholar
  3. Casaer MP, Mesotten D, Hermans G, Wouters PJ, Schetz M, Meyfroidt G, Van Cromphaut S, Ingels C, Meersseman P, Muller J, Vlasselaers D, Debaveye Y, Desmet L, Dubois J, Van Assche A, Vanderheyden S, Wilmer A, Van den Berghe GN (2011) Early versus late parenteral nutrition in critically ill adults. Engl J Med. 365(6):506–17. Epub 2011 Jun 29Google Scholar
  4. Clifton GL, Robertson CS, Choi SC (1986) Assessment of nutritional requirements of head-injured patients. J Neurosurg 64:895–901PubMedCrossRefGoogle Scholar
  5. Cochran A, Scaife ER, Hansen KW, Downey EC (2003) Hyperglycemia and outcomes from pediatric traumatic brain injury. J Trauma 55:1035–1038PubMedCrossRefGoogle Scholar
  6. Cook AM, Peppard A, Magnuson B (2008) Nutrition considerations in traumatic brain injury. Nutr Clin Pract 23:608–620PubMedCrossRefGoogle Scholar
  7. Frankenfield D, Hise M, Malone A, Russell M, Gradwell E, Compher C (2007) Prediction of resting metabolic rate in critically ill adult patients: results of a systematic review of the evidence. J Am Diet Assoc 107:1552–1561PubMedCrossRefGoogle Scholar
  8. Fraser RJ, Bryant L (2010) Current and future therapeutic prokinetic therapy to improve enteral feed intolerance in the ICU patient. Nutr Clin Pract 25:26–31PubMedCrossRefGoogle Scholar
  9. Griffiths RD (2007) Too much of a good thing: the curse of overfeeding. Crit Care 11:176PubMedCrossRefGoogle Scholar
  10. Heyland DK, Dhaliwal R, Drover JW, Gramlich L, Dodek P (2003) Canadian clinical practice guidelines for nutrition support in mechanically ventilated, critically ill adult patients. JPEN J Parenter Enteral Nutr 27:355–373PubMedCrossRefGoogle Scholar
  11. Ishibashi N, Plank LD, Sando K, Hill GL (1998) Optimal protein requirements during the first 2 weeks after the onset of critical illness. Crit Care Med 26:1529–1535PubMedCrossRefGoogle Scholar
  12. Kansagara D, Fu R, Freeman M, Wolf F, Helfand M (2011) Intensive insulin therapy in hospitalized patients: a systematic review. Ann Intern Med 154:268–282PubMedGoogle Scholar
  13. Kondrup J, Rasmussen HH, Hamberg O, Stanga Z (2003) Nutritional risk screening (NRS2002): a new method based on an analyses of controlled clinical trials. Clin Nutr. 22:321–336PubMedCrossRefGoogle Scholar
  14. Kurien M, McAlindon ME, Westaby D, Sanders DS (2010) Percutaneous endoscopic gastrostomy (PEG) feeding. BMJ 340:c2414PubMedCrossRefGoogle Scholar
  15. Larsson J, Lennmarken C, Martensson J, Sandstedt S, Vinnars E (1990) Nitrogen requirements in severely injured patients. Br J Surg 77:413–416PubMedCrossRefGoogle Scholar
  16. Lochs H, Allison SP, Meier R, Pirlich M, Kondrup J, Schneider S, van den Berghe G, Pichard C (2006) Introductory to the ESPEN guidelines on enteral nutrition: terminology, definitions and general topics. Clin Nutr 25:180–186PubMedCrossRefGoogle Scholar
  17. Meierhans R, Bechir M, Ludwig S, Sommerfeld J, Brandi G, Haberthur C, Stocker R, Stover JF (2010) Brain metabolism is significantly impaired at blood glucose below 6 mM and brain glucose below 1 mM in patients with severe traumatic brain injury. Crit Care 14:R13PubMedCrossRefGoogle Scholar
  18. Nguyen NQ, Chapman MJ, Fraser RJ, Bryant LK, Holloway RH (2007) Erythromycin is more effective than metoclopramide in the treatment of feed intolerance in critical illness. Crit Care Med 35:483–489PubMedCrossRefGoogle Scholar
  19. Sabotka L (2004) Basics in clinical nutrition. Publishing House Galen, PragueGoogle Scholar
  20. Seron Arbeloa C, Avellanas Chavala M, Homs Gimeno C, Larraz Vileta A, Laplaza Marin J, Puzo Foncillas J (1999) Evaluation of a high protein diet in critical care patients. Nutr Hosp 14:203–209PubMedGoogle Scholar
  21. Singer P, Anbar R, Cohen J, Shapiro H, Shalita-Chesner M, Lev S, Grozovski E, Theilla M, Frishman S, Madar Z (2011) The tight calorie control study (TICACOS): a prospective, randomized, controlled pilot study of nutritional support in critically ill patients. Intensive Care Med 37:601–609PubMedCrossRefGoogle Scholar
  22. Singer P, Berger MM, Van den Berghe G, Biolo G, Calder P, Forbes A, Griffiths R, Kreyman G, Leverve X, Pichard C, ESPEN (2009) ESPEN guidelines on parenteral nutrition: intensive care. Clin Nutr 28:387–400PubMedCrossRefGoogle Scholar
  23. Streat SJ, Hill GL (1987) Nutritional support in the management of critically ill patients in surgical intensive care. World J Surg 11:194–201PubMedCrossRefGoogle Scholar
  24. Turner P (2010) Providing optimal nutritional support on the intensive care unit: key challenges and practical solutions. Proc Nutr Soc 69:574–581PubMedCrossRefGoogle Scholar
  25. Twyman D, Young AB, Ott L, Norton JA, Bivins BA (1985) High protein enteral feedings: a means of achieving positive nitrogen balance in head injured patients. JPEN J Parenter Enteral Nutr 9:679–684PubMedCrossRefGoogle Scholar
  26. Wolfe RR, Goodenough RD, Burke JF, Wolfe MH (1983) Response of protein and urea kinetics in burn patients to different levels of protein intake. Ann Surg 197:163–171PubMedCrossRefGoogle Scholar
  27. Yang DL, Xu JF (2007) Effect of dipeptide of glutamine and alanine on severe traumatic brain injury. Chin J Traumatol 10:145–149PubMedGoogle Scholar
  28. Young B, Ott L, Twyman D, Norton J, Rapp R, Tibbs P, Haack D, Brivins B, Dempsey R (1987) The effect of nutritional support on outcome from severe head injury. J Neurosurg 67:668–676PubMedCrossRefGoogle Scholar
  29. Young B, Ott L, Kasarskis E, Rapp R, Moles K, Dempsey RJ, Tibbs PA, Kryscio R, McClain C (1996) Zinc supplementation is associated with improved neurologic recovery rate and visceral protein levels of patients with severe closed head injury. J Neurotrauma 13:25–34PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Anne Berit Guttormsen
    • 1
    • 2
  • Bram de Hoog
    • 1
  • Jennie Hernæs
    • 3
  1. 1.Department of Anaesthesia and Intensive CareHaukeland University HospitalBergenNorway
  2. 2.Department of Surgical Sciences, Section of AnaesthesiologyUniversity of BergenBergenNorway
  3. 3.Department of Clinical NutritionHaukeland University HospitalBergenNorway

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