Neuromarkers

  • Ramona Åstrand
  • Johan Undén
  • Peter Reinstrup
  • Bertil Romner
Chapter

Abstract

Traumatic brain injury (TBI) is a significant cause of mortality and morbidity in adults and a leading cause of death in childhood. The diagnostic process includes clinical examination and in more severe cases neuroimaging, such as computed tomography of the head (CT) or magnetic resonance imaging (MRI). Biochemical markers are constantly being used as diagnostic tools for injuries in specific organs, such as troponin for myocardial infarction, creatinine for renal dysfunction and pancreas amylase and lipase for acute pancreatitis. A biomarker detectable in serum, and easily analysed, would be preferable as a complement to clinical assessment after TBI.

Keywords

Traumatic Brain Injury Acute Pancreatitis Glial Fibrillary Acidic Protein Brain Death Unfavourable Outcome 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Ramona Åstrand
    • 1
  • Johan Undén
    • 2
  • Peter Reinstrup
    • 3
  • Bertil Romner
    • 1
  1. 1.Department of Neurosurgery, 2092RigshospitaletCopenhagenDenmark
  2. 2.Department of Anesthesia and Intensive CareSkåne University Hospital MalmöMalmöSweden
  3. 3.Department of AnesthesiologySkåne University Hospital LundLundSweden

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