Near Infrared Spectroscopy (NIRS) or Cerebral Oximetry

  • Peter Reinstrup
  • Bertil Romner


Near infrared spectroscopy (NIRS) measures the oxygenation of the haemoglobin in the cerebral tissue lying just underneath a probe. The probe is most often placed on the forehead since hair follicles affect the readings. Some doubts have been raised whether NIRS specifically measures the cerebral tissue or is contaminated by signals from extracerebral tissue it passes through. Furthermore, as haemoglobin absorbs infrared light, NIRS is affected by underlying blood of extravascular origin, such as in subdural haematomas, contusions, subarachnoid blood, as well as changes in cerebral blood volume (CBV). These factors are difficult to decipher, and at present the use of NIRS in TBI patients is controversial. However, by using more than one sensor and by focusing on trends, NIRS readings might be of value in this patient group.


Cerebral Blood Flow Hair Follicle Subdural Haematoma Cerebral Blood Volume Mean Transit Time 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. Al-Rawi PG, Kirkpatrick PJ (2006) Tissue oxygen index: thresholds for cerebral ischemia using near-infrared spectroscopy. Stroke 37:2720–2725PubMedCrossRefGoogle Scholar
  2. Canova D, Roatta S, Bosone D, Micieli G (2011) Inconsistent detection of changes in cerebral blood volume by near infrared spectroscopy in standard clinical tests. J Appl Physiol 110(6):1646–55, Epub 2011 Apr 7PubMedCrossRefGoogle Scholar
  3. Dunham CM, Sosnowski C, Porter JM, Siegal J, Kohli C (2002) Correlation of noninvasive cerebral oxymetry with cerebral perfusion in the severe head injured patient: a pilot study. J Trauma 52:40–46PubMedCrossRefGoogle Scholar
  4. Ferrari M, Giannini I, Sideri G, Zanette E (1985) Continous non invasive monitoring of human brain by near infrared spectoscopy. Adv Exp Med Biol 191:873–882PubMedGoogle Scholar
  5. Gopinath SP, Robertson CS, Contant CF, Narayan RK, Grossman RG, Chance B (1995) Early detection of delayed traumatic intracranial hematomas using near-infrared spectroscopy. J Neurosurg 83(3):438–444PubMedCrossRefGoogle Scholar
  6. Jobsis FF (1977) Noninvasive infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters. Science 198:1264–1267PubMedCrossRefGoogle Scholar
  7. Keller E, Nadler A, Alkadhi H, Kollias SS, Yonekawa Y, Niederer P (2003) Noninvasive measurement of regional cerebral blood flow and regional cerebral blood volume by near-infrared spectroscopy and indocyanine green dye dilution. Neuroimage 20:828–839PubMedCrossRefGoogle Scholar
  8. Kim MB, Ward DS, Cartwright CR, Kolano J, Chlebowski S, Henson LC (2000) Estimation of jugular venous O2 saturation from cerebral oximetry or arterial O2 saturation during isocapnic hypoxia. J Clin Monit Comput 16(3):191–199PubMedCrossRefGoogle Scholar
  9. Kuebler WM, Sckell A, Habler O, Kleen M, Kuhnle GE, Welte M, Messmer K, Goetz AE (1998) Noninvasive measurement of regional cerebral blood flow by near-infrared spectroscopy and indocyanine green. J Cereb Blood Flow Metab 18:445–456PubMedCrossRefGoogle Scholar
  10. Newton CR, Wilson DA, Gunnoe E, Wagner B, Cope M, Traystman RJ (1997) Measurement of cerebral blood flow in dogs with near infrared spectroscopy in the reflectance mode is invalid. J Cereb Blood Flow Metab 17(6):695–703PubMedCrossRefGoogle Scholar
  11. Young AER, Germon TJ, Barnett NJ, Manara AR, Nelson RJ (2000) Behaviour of near-infrared light in the adult human head: implications for clinical near-infra red spectroscopy. Br J Anaesth 84:38–42PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  1. 1.Department of Intensive and Perioperative CareSkanes University HospitalLundSweden
  2. 2.Department of Neurosurgery 2092RigshospitaletCopenhagenDenmark

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