Permacol in Augmentation Rhinoplasty

  • Claire Hopkins
  • David Roberts


Permacol™ is a sheet of acellular cross-linked porcine dermal collagen and its constituent elastin fibres. It is readily available as a graft material for augmentation rhinoplasty, with low risk of infection, extrusion or transmission of disease. It may be used as a single sheet for camouflaging irregularities or in rolled form when a greater volume of augmentation is required. The authors have had excellent results using Permacol in over 100 patients over an 8-year period and believe it to be an ideal graft material for augmentation rhinoplasty. The manufacturing process produces a graft that is resistant to collagenase and is sterilized by gamma irradiation.

The ideal graft material for augmentation should be readily available in the required volume and economical. It should provide volume replacement that is stable over time; it should be easy to shape and should maintain the structural integrity of the nose. It must be biocompatible and should not cause discolouration of the overlying skin, become infected or extruded. Permacol™ is a sheet of acellular cross-linked porcine dermal collagen and its constituent elastin fibres. The graft is sterilized, thus reducing infection risks.


Nasal Dorsum Lower Lateral Cartilage Volume Augmentation Autologous Cartilage Dice Cartilage 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  1. 1.OrpingtonUK
  2. 2.Rhinological Unit, ENT DepartmentGuy’s and St. Thomas’ HospitalLondonUK

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