The Use of Urea in the Treatment of Dry Skin

  • Marie Lodén


Moisturizers have different effects on the skin structure and function. Moisturizers that reduce the signs of dryness and strengthen skin barrier function are believed to also reduce the prevalence of inflammatory dermatosis.

The naturally occurring humectant urea has been reported to both enhance and retard the penetration. In the majority, but not all clinical and experimental studies on urea, improvement of dryness and skin barrier function has been noted. A moisturizer with urea has also been shown to delay relapse of eczema in atopic patients and in patients with hand eczema. The treatment has been found cost-effective compared with no treatment in adult patients with atopic dermatitis in the four Nordic countries.


Atopic Dermatitis Stratum Corneum Hand Eczema Atopic Patient Skin Barrier Function 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  1. 1.Eviderm Institute AB, Research and DevelopmentSolnaSweden

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