Abstract
The aim of this study was to evaluate the the biocompatibility properties of central vein catheter following radiation sterilisation (8.8kGy).we conducted a series of tests including cytotoxicity, sensitisation, intracutaneous irritation test, local reaction test after implantation and tests of properties of the packaging materials. The results show that after the irradiation and accelerated ageing tests, the sample products and the package remained effective. No toxic or sensitising substances or particles were released from the central vein catheter after radiation sterilisation. After simulated storage and radiation sterilisation with the setting dose, neither physicochemical properties nor packaging capability of sample products were significantly changed, indicating that the product material is relatively stable for radiation. Therefore, radiation sterilisation is a useful method to these kind of materials, and is worth generalising and applying more widely.
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© 2011 Springer-Verlag Berlin Heidelberg
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Liu, W., Liu, Q., Chen, G. (2011). Evaluation of the Effects of Sterilization by Irradiation on Histocompatibility and Adaption of a Central Vein Catheter. In: Liu, C., Chang, J., Yang, A. (eds) Information Computing and Applications. ICICA 2011. Communications in Computer and Information Science, vol 244. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27452-7_20
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DOI: https://doi.org/10.1007/978-3-642-27452-7_20
Publisher Name: Springer, Berlin, Heidelberg
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