Diabetic Macular Edema

  • Conceição Lobo
  • Isabel Pires
  • José Cunha-Vaz
Part of the Biological and Medical Physics, Biomedical Engineering book series (BIOMEDICAL)


The optical coherence tomography (OCT), a noninvasive and noncontact diagnostic method, was introduced in 1995 for imaging macular diseases. In diabetic macular edema (DME), OCT scans show hyporeflectivity, due to intraretinal and/or subretinal fluid accumulation, related to inner and/or outer blood–retinal barrier breakdown. OCT tomograms may also reveal the presence of hard exudates, as hyperreflective spots with a shadow, in the outer retinal layers, among others. In conclusion, OCT is a particularly valuable diagnostic tool in DME, helpful both in the diagnosis and follow-up procedure.


Optical Coherence Tomography Diabetic Retinopathy Macular Edema Retinal Nerve Fiber Layer Diabetic Macular Edema 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Conceição Lobo
    • 1
  • Isabel Pires
    • 1
  • José Cunha-Vaz
    • 1
  1. 1.AIBILI-Association for Innovation and Biomedical Research on Light and ImageCoimbraPortugal

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