Polyethylene Wear in Metal-Backed Cups: A Retrospective Analysis of 200 Uncemented Prostheses

  • Walter van der Weegen
  • Shennah Austen
  • Thea Sijbesma
  • Henk J. Hoekstra


Uncemented total hip prostheses were introduced some 40 years ago, after disappointing results with cemented hip prostheses in young and active patients. In orthopedic literature, research on uncemented hip prostheses has focused on the survival of the uncemented femoral stem, and in general, excellent results were reported. Although the femoral component showed excellent performance, recent in vivo studies have reported increased wear of the polyethylene (PE) liner of the uncemented acetabular cup. This PE wear results in PE particles being distributed in the tissue surrounding the prosthesis, with macrophages being activated by these particles. These activated macrophages induce osteolysis (see Fig. 9.1) which in the end results in aseptic loosening of the prosthesis.


Femoral Component Aseptic Loosening Acetabular Component Liner Wear Conventional UHMWPE 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© EFORT 2012

Authors and Affiliations

  • Walter van der Weegen
    • 1
  • Shennah Austen
    • 2
  • Thea Sijbesma
    • 3
  • Henk J. Hoekstra
    • 3
  1. 1.Department of Orthopedic SurgerySt. Anna HospitalGeldropThe Netherlands
  2. 2.Department of Orthopedic SurgeryUniversity of MaastrichtMaastrichtThe Netherlands
  3. 3.Department of Orthopedic SurgerySt. Anna HospitalGeldropThe Netherlands

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