Computer-Aided Detection of Diabetic Retinopathy Progression
It is considered crucial for diabetic retinopathy (DR) management to identify disease progression in clinical practice. Automated computer-aided analysis of fundus digital photographs giving microaneurysm formation and disappearance rates together with OCT measurements of extracellular space and retinal thickness, both based on non-invasive procedures allow close follow-up of the main alterations occurring in the diabetic retina: microaneurysm turnover, capillary closure and alteration of blood-retinal barrier. Determination of the activity of the retinal disease and individual risk profiles using non-invasive procedures is expected to contribute to personalized management of diabetic retinopathy and prevent its vision-threatening complications, macular oedema and proliferative retinopathy. Finally, automated computer-aided analysis of fundus digital photographs, namely, the Retmarker, offers a promising contribution to reduce the burden of manual grading in DR screening programmes.
KeywordsDiabetic Retinopathy Macular Oedema Probability Density Function Proliferative Retinopathy Diabetic Retina
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