Brain Tissue Oxygen Monitoring in Neurocritical Care

  • P. Geukens
  • M. Oddo
Part of the Annual Update in Intensive Care and Emergency Medicine book series (AUICEM, volume 2012)


Avoidance of secondary cerebral hypoxia/ischemia is a mainstay of therapy in neurocritical care. On-line monitoring of brain tissue oxygen tension (PbtO2) enables detection of secondary brain hypoxic/ischemic insults and targeting of therapeutic interventions, such as intracranial pressure (ICP) control, cerebral perfusion pressure (CPP) augmentation, blood transfusion, and ventilation. Emerging evidence shows that compared to standard ICP/CPP management, PbtO2-directed therapy may improve outcomes of selected populations of brain-injured patients. Larger prospective multicenter trials are underway to further evaluate the potential benefit of PbtO2-directed therapy.


Traumatic Brain Injury Cerebral Perfusion Pressure Severe Traumatic Brain Injury Brain Hypoxia Brain Oxygen 
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© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • P. Geukens
  • M. Oddo

There are no affiliations available

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