Metabolomics in Critically ill Patients: Focus on Exhaled Air

  • L. D. J. Bos
  • P. J. Sterk
  • M. J. Schultz
Part of the Annual Update in Intensive Care and Emergency Medicine book series (AUICEM, volume 2012)


The lungs of critically ill patients are under constant threat. Critically ill patients may develop acute lung injury (ALI) or its more severe form, acute respiratory distress syndrome (ARDS). Development of ALI/ARDS frequently mandates tracheal intubation for mechanical ventilation [1]. Tracheal intubation, however, carries the risk of ventilator-associated pneumonia (VAP) [2], whereas mechanical ventilation has the potential to cause so-called ventilator-associated lung injury (VALI) [3]. ALI/ARDS and VALI are diagnosed according to the American-European consensus criteria, which include bilateral pulmonary infiltrates on chest radiography and hypoxia [4].


Acute Lung Injury Acute Respiratory Distress Syndrome Biological Marker Respir Crit Electronic Nose 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • L. D. J. Bos
  • P. J. Sterk
  • M. J. Schultz

There are no affiliations available

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