Urine Output and the Diagnosis of Acute Kidney Injury

  • J. R. Prowle
  • R. Bellomo
Part of the Annual Update in Intensive Care and Emergency Medicine book series (AUICEM, volume 2012)

Abstract

Prevention and management of organ dysfunction are central to the practice of critical care medicine. To this end, physiological monitoring is used to assess organ function and the effects of treatment in real time. One of the foremost challenges for the intensive care specialist is to understand how to relate physiological variables, such as oxygenation, blood pressure and cardiac output, to underlying organ function. These relationships are complex and reflect interdependence of organ function, treatment, disease and comorbid conditions. Nevertheless, in search of patterns to guide clinical management, we commonly relate certain measurements to the function of particular organs, such as blood pressure and cardio-circulatory function. In the case of the kidneys, maintenance of urine output is a continuous manifestation of organ function and urine production is both monitored as an index of organ function and targeted as a therapeutic goal. However, in common with other continuously monitored physiological variables, the relationship between urine output and underlying kidney function is complex and there are many pitfalls to its interpretation in isolation.

Keywords

Renal Replacement Therapy Acute Kidney Injury Urine Output Renal Blood Flow Renal Plasma Flow 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • J. R. Prowle
  • R. Bellomo

There are no affiliations available

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