Subclinical Damage in Acute Kidney Injury: A Novel Paradigm

  • S. M. Bagshaw
  • M. Haase
Part of the Annual Update in Intensive Care and Emergency Medicine book series (AUICEM, volume 2012)


Acute kidney injury (AKI) remains a challenging clinical problem for clinicians caring for critically ill patients. Its occurrence in the critically ill is remarkably common, frequently iatrogenic, and it consistently predicts an increase in the complexity and intensity of care. Moreover, AKI appears to consistently have a negative impact on both short and long-term survival and recovery of kidney function, along with greatly intensifying health resource utilization [1, 2]. Accordingly, there has been considerable effort to better understand the pathophysiology and improve the outcomes associated with the development of AKI.


Renal Replacement Therapy Acute Kidney Injury Fractional Excretion Tubular Damage Acute Kidney Injury Network 
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© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • S. M. Bagshaw
  • M. Haase

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