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Blood Lactate Levels: A Manual for Bedside Use

  • J. Bakker
  • T. C. Jansen
Part of the Annual Update in Intensive Care and Emergency Medicine book series (AUICEM, volume 2012)

Abstract

In the first description of increased lactate levels in human beings [1], Joseph Scherer analyzed blood drawn from young women who had just died from what we now call septic shock. Since then increased levels and delayed clearance have been associated with many measures of morbidity and mortality [2, 3]. However, the source of increased lactate levels and/or the cause of its delayed clearance is not linked to one specific pathological process that, when positively influenced by therapy, will change lactate levels and improve outcome. Therefore, the clinical use of lactate levels to improve outcome of critically ill patients is subject to ongoing discussion. To use the complex signal of increased lactate levels and/or delayed clearance the clinician needs to understand the metabolism of lactate.

Keywords

Septic Shock Lactate Level Arterial Oxygen Saturation Blood Lactate Level Lactate Clearance 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • J. Bakker
  • T. C. Jansen

There are no affiliations available

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