TRUE Test System

  • Jean-Marie Lachapelle
  • Howard I. Maibach


Conventional patch testing technology has been fully described in Chap. 3. The method is extensively used by the dermatological community throughout the world. A potential drawback is that allergens are not always evenly dispersed in petrolatum. This is illustrated by histological examination of different samples; indeed, allergen crystals of different size can be visualized. Nevertheless, the situation has improved considerably, in relation with the use of more performant machinery in the manufacture of allergens. On the other hand, the dosage of allergens may vary in different areas, as the allergens are manually dispensed. TRUE Test represents an alternative way of patch testing, which intends to avoid variations of the allergens applied on the skin.


Patch Testing Transepidermal Water Loss Specific Allergen Gold Sodium Hydroxypropyl Cellulose 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Jean-Marie Lachapelle
    • 1
  • Howard I. Maibach
    • 2
  1. 1.Department of DermatologyCatholic University of LouvainBrusselsBelgium
  2. 2.Department of Dermatology, School of MedicineUniversity of CaliforniaSan FranciscoUSA

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