Testing Procedures in Cutaneous Systemic Immune-Related Adverse Drug Reactions

  • Jean-Marie Lachapelle


Cutaneous adverse drug reactions (CADRs) to systemically administered drugs have increased in number during the last few years. This is due to the expanding number of new active molecules used in the treatment of a variety of diseases. CADRs are varied and described in full detail in oriented manuals of dermatology.

Diagnosis of CADR may be straightforward in some cases but less obvious in some others. The link between the occurrence of a CADR and the systemic administration of a drug (considered to be the culprit agent) is sometimes difficult to assess. The problem is even more complex when several drugs are administrated concomitantly. Several criteria can be taken into account to find the relationship between drug administration and the occurrence of CADRs.


Patch Test Allergic Contact Dermatitis Pure Drug Intradermal Test Patch Test Reaction 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Jean-Marie Lachapelle
    • 1
  1. 1.Department of DermatologyCatholic University of LouvainBrusselsBelgium

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