In Vitro Research and Development

  • University College NHS Foundation Trust and University College London


From the outset the work of the Institute was divided into that where a specimen from a patient (blood, urine CSF, et.) was the basic material for study and that where investigations were carried out on a patient in person: “in vivo” studies. In routine diagnostic tests both were often required. For example in thyroid function testing, not only was the thyroid uptake of an administered dose of radioactive iodine measured but also a blood sample was obtained and the radioactive iodine bound to the blood proteins measured using an end-window Geiger-Muller(GM) counter. However, the research projects fell reasonably into one or other group.


Thyroid Stimulate Hormone Radioactive Iodine Thyroid Function Test Thyroid Uptake Thyroxine Binding Globulin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    A simple microdiffusion technique for the radioiodination of proteins. R.N. Bannerjee, and R.P. Ekins, Nature, 192, 746–747, 1967.CrossRefGoogle Scholar
  2. 2.
    The estimation of thyroxine in human plasma by an electrophoretic technique. R.P. Ekins, Clinica Chimica Acta, 5, 453–459, 1960.CrossRefGoogle Scholar
  3. 3.
    The assay of vitamin B12 in blood: a sample method. R.M. Barkat, and R.P. Ekins. Lancet, II, 25–26, 1961.CrossRefGoogle Scholar
  4. 4.
    The fundamental principles governing the attainment of high sensitivity and precision in radioimmunoassay techniques and their exemplification in a method for the assay of serum insulin. J. Albano, and R.P. Ekins. Acta Endorcrinologica Supplement 138, 61, 1969.Google Scholar
  5. 5.
    A strategy for thyroid function tests. K.E. Britton, V. Quinn, B.L. Brown and R.P. Ekins. British Medical Journal, iii, 350–352, 1975.CrossRefGoogle Scholar
  6. 6.
    The radioimmunoassay of serum free tri-iodothyroxine and thyroxine in Radioimmunoassay in Clinical Biochemistry, (ed. C.A. Pasternak), 187–194, 1975.Google Scholar
  7. 7.
    The radioimmunoassay of free thyroid hormones in serum. R.P. Ekins, and S.M. Ellis in Thyroid Research, (eds. J. Robbins and L.E. Braverman), 597–600, 1976.Google Scholar
  8. 8.
    More sensitive immunoassays. R.P. Ekins. Nature, 14–15, 1980.Google Scholar
  9. 9.
    Pulsed-light, time-resolved fluoroimmunoassay. N.J. Marshall, S. Dakubu T. Jackson, and R.P. Ekins. In Monoclonal antibodies and developments in immunoassay, (eds. A. Albertini and R.P.Ekins), 101–108, 1981.Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • University College NHS Foundation Trust and University College London

There are no affiliations available

Personalised recommendations